Interleukin-6 receptor and its ligand interleukin-6 are opposite markers for survival and infiltration with mature myeloid cells in ovarian cancer.

Autor: Wouters, MCA^1,2, Dijkgraaf, EM³, Kuijjer, ML^4,5, Jordanova, ES⁶, Hollema, H⁷, Welters, MJP³, van der Hoeven, JJM³, Daemen, T², Kroep, JR³, Nijman, HW¹, van der Burg, SH³

Publikováno v: OncoImmunology. Dec2014, Vol. 3 Issue 12, pN.PAG-N.PAG. 1p.

A phase 1/2 study combining gemcitabine, Pegintron and p53 SLP vaccine in patients with platinum-resistant ovarian cancer.

Autor: Dijkgraaf EM; Department of Medical Oncology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Santegoets SJ; Department of Medical Oncology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Reyners AK; Department of Clinical Oncology, University Medical Center Groningen, University of Groningen, 9713 GZ, Groningen, The Netherlands., Goedemans R; Department of Medical Oncology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Nijman HW; Department of Gynecologic Oncology, University Medical Center Groningen, University of Groningen, 9713 GZ, Groningen, The Netherlands., van Poelgeest MI; Department of Gynecology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., van Erkel AR; Department of Radiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Smit VT; Department of Pathology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Daemen TA; Department of Medical Microbiology, University Medical Center Groningen, University of Groningen, 9713 GZ, Groningen, The Netherlands., van der Hoeven JJ; Department of Medical Oncology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Melief CJ; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Welters MJ; Department of Medical Oncology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Kroep JR; Department of Medical Oncology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., van der Burg SH; Department of Medical Oncology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.

Publikováno v: Oncotarget [Oncotarget] 2015 Oct 13; Vol. 6 (31), pp. 32228-43.

Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry.

Autor: Santegoets SJ; Department of Clinical Oncology, Leiden University Medical Center (LUMC), Leiden, The Netherlands, s.j.a.m.santegoets@lumc.nl., Dijkgraaf EM, Battaglia A, Beckhove P, Britten CM, Gallimore A, Godkin A, Gouttefangeas C, de Gruijl TD, Koenen HJ, Scheffold A, Shevach EM, Staats J, Taskén K, Whiteside TL, Kroep JR, Welters MJ, van der Burg SH

Publikováno v: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2015 Oct; Vol. 64 (10), pp. 1271-86. Date of Electronic Publication: 2015 Jun 28.

Thyroid function alters during neoadjuvant chemotherapy in breast cancer patients: results from the NEOZOTAC trial (BOOG 2010-01).

Autor: de Groot S; Department of Clinical Oncology, Leiden University Medical Center, Abinusdreef 2, P.O. Box 9600, 2300 RC, Leiden, The Netherlands, s.de_groot2@lumc.nl., Janssen LG, Charehbili A, Dijkgraaf EM, Smit VT, Kessels LW, van Bochove A, van Laarhoven HW, Meershoek-Klein Kranenbarg E, van Leeuwen-Stok AE, van de Velde CJ, Putter H, Nortier JW, van der Hoeven JJ, Pijl H, Kroep JR

Publikováno v: Breast cancer research and treatment [Breast Cancer Res Treat] 2015 Jan; Vol. 149 (2), pp. 461-6. Date of Electronic Publication: 2015 Jan 04.

Chemotherapy alters monocyte differentiation to favor generation of cancer-supporting M2 macrophages in the tumor microenvironment.

Autor: Dijkgraaf EM; Department of Clinical Oncology, Leiden University Medical Center, Albinusdreef, Leiden, The Netherlands., Heusinkveld M, Tummers B, Vogelpoel LT, Goedemans R, Jha V, Nortier JW, Welters MJ, Kroep JR, van der Burg SH

Publikováno v: Cancer research [Cancer Res] 2013 Apr 15; Vol. 73 (8), pp. 2480-92. Date of Electronic Publication: 2013 Feb 22.