Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Dihydrocodeinone"'
Autor:
Damien Maurel, Christian Gentzsch, Sébastien Granier, Kerstin Seier, Harald Hübner, Yann Lanoiselée, Zsombor Koszegi, Davide Calebiro, Peter Gmeiner, Michael Decker, Marie-Lise Jobin, Antonios Drakopoulos, Remy Sounier
Publikováno v:
Angewandte Chemie (International Ed. in English)
μ‐Opioid receptors (μ‐ORs) play a critical role in the modulation of pain and mediate the effects of the most powerful analgesic drugs. Despite extensive efforts, it remains insufficiently understood how μ‐ORs produce specific effects in liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f229060f97399ea8d271b86c2366c9
https://doi.org/10.1002/ange.201912683
https://doi.org/10.1002/ange.201912683
Autor:
Helena Hulkova, Monika Arenbergerova, J. Sikora, O. Trhlikova, Spyridon Gkalpakiotis, P. Arenberger, Eva Sticova
Publikováno v:
Journal of the European Academy of Dermatology and Venereology : JEADVReferences. 34(1)
Background 'Braun' is an illegal injectable dihydrocodeinone-enriched drug mixture of semi-synthetic opioids. It is prepared by palladium-catalysed hydrogenation from codeine-containing tablets. Objective We aimed to characterize the dermatologic con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb34cade646bd6a98215e6d929b57648
https://pubmed.ncbi.nlm.nih.gov/31494978
https://pubmed.ncbi.nlm.nih.gov/31494978
Autor:
Zsombor Koszegi, Marie-Lise Jobin, Harald Hübner, Sébastien Granier, Antonios Drakopoulos, Yann Lanoiselée, Kerstin Seier, Davide Calebiro, Damien Maurel, Peter Gmeiner, Remy Sounier, Christian Gentzsch, Michael Decker
Publikováno v:
Angewandte Chemie. 132:6348-6348
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::120def8f939aedcc4ad565fcc47caed9
https://doi.org/10.1002/ange.202002281
https://doi.org/10.1002/ange.202002281
Autor:
Michael Decker, Sébastien Granier, Kerstin Seier, Davide Calebiro, Christian Gentzsch, Remy Sounier, Damien Maurel, Marie-Lise Jobin, Antonios Drakopoulos, Harald Hübner, Zsombor Koszegi, Yann Lanoiselée, Peter Gmeiner
Publikováno v:
Angewandte Chemie International Edition. 59:6289-6289
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d297201906b3ab3c185703394491b4b9
https://doi.org/10.1002/anie.202002281
https://doi.org/10.1002/anie.202002281
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 102:135-139
The Delft total synthesis of morphinans starts from 1-benzylisoquinolines (Scheme 2, 7) and gives both the morphinans with the natural (-)-morphine configuration and the corresponding enantiomers. This route has been used as a basis for an improved s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d60335a63ec75035b9f0ed217ddcb943
https://doi.org/10.1002/recl.19831020303
https://doi.org/10.1002/recl.19831020303
Publikováno v:
Synlett. 2007:2863-2867
Enzymatic dihydroxylation of b-bromoethylbenzene provided a homochiral diene diol that served as starting material for the synthesis of the complete morphinan skeleton via an intramolec- ular Heck cyclization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::644664768854c1b6bc9f896990f0124a
https://doi.org/10.1055/s-2007-990832
https://doi.org/10.1055/s-2007-990832
Autor:
Demosthenes Fokas, Kathlyn A. Parker
Publikováno v:
The Journal of Organic Chemistry. 71:449-455
[reaction: see text] The radical cyclization approach to the morphine alkaloids has been applied in an asymmetric synthesis of (-)-dihydrocodeinone. A chiral cyclohexenol (R-32), from the CBS reduction of the enone, is the source of chirality. The fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ab931a5c14e17378a9ca7393df23fbe
https://doi.org/10.1021/jo0513008
https://doi.org/10.1021/jo0513008
Publikováno v:
The Journal of Organic Chemistry. 70:6492-6495
Improved protocols for the preparation of 1-bromodihydrocodeinone (1-bromohydrocodone) and 1-bromo-14-hydroxydihydrocodeinone (1-bromooxycodone) and synthesis of the corresponding 1-chloro and 1-iodo derivatives have been achieved using the correspon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2ec422b2b8995e7ebca23be000ead1c
https://doi.org/10.1021/jo050264+
https://doi.org/10.1021/jo050264+
Autor:
Mellar P. Davis, Jade Homsi, Susan B. LeGrand, Declan Walsh, Nabeel Sarhill, Lisa Rybicki, Kristine A. Nelson
Publikováno v:
American Journal of Hospice and Palliative Medicine®. 19:49-56
Purpose: Cough is a common symptom in advanced cancer. The use of hydrocodone as an antitussive has not been studied previously in this setting. This study evaluates hydrocodone for cough in advanced cancer. Methods: The results presented are from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb9085690208859f5403cc4b7ac093e
https://doi.org/10.1177/104990910201900110
https://doi.org/10.1177/104990910201900110
Publikováno v:
Pure and Applied Chemistry. 70:1487-1493
The concept of molecular workbenches1 is introduced and outlined in Figure 1. According to the distinction between disconnectible and non-disconnectible workbenches this account falls into two sections, the first one describing the application of aux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76229cd0a010bcd544cdc111a8a46684
https://doi.org/10.1351/pac199870081487
https://doi.org/10.1351/pac199870081487