Zobrazeno 1 - 10
of 5 497
pro vyhledávání: '"Dihydroartemisinin"'
Autor:
Tingting Liu, Dan Zheng, Jing Wang, Xin Li, Shasha Yu, Zhilong Liu, Feifei Zheng, Caizhi Zhao, Xuesen Yang, Ying Wang
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Background Malaria is a serious public health concern. Artemisinin and its derivatives are first-line drugs for the treatment of Plasmodium falciparum malaria. In mammals, artemisinin exhibits potent anti-inflammatory and immunoregulatory pr
Externí odkaz:
https://doaj.org/article/37c917b67b17420881572515ab83cadc
Autor:
Helena D’Anunciação de Oliveira, Camila Nunes Batista, Maiara Nascimento Lima, Ana Carolina Lima, Beatriz Amanda Barbosa Rangel dos Passos, Rodrigo Jose Rocha Xavier Freitas, Johnatas Dutra Silva, Debora Gonçalves Xisto, Marcos Vinícius Rangel-Ferreira, Marcelo Pelajo, Patricia Rieken Macedo Rocco, Flávia Lima Ribeiro-Gomes, Hugo Caire de Castro Faria-Neto, Tatiana Maron-Gutierrez
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Severe malaria can cause respiratory symptoms, which may lead to malaria-acute lung injury (MA-ALI) due to inflammation and damage to the blood-gas barrier. Patients with severe malaria also often present thrombocytopenia, and the
Externí odkaz:
https://doaj.org/article/3e638df23889482182888072dd2634ff
Autor:
Swaraj Kumar Babu, Sameer Maharana, Satyaranjan Chhatria, Dibya Ranjan Sahoo, Ashirbad Nanda, Satish Kanhar, Prativa K. Behera, Sanjib Mohanty, Pradeep Kumar Naik, Praveen Kishore Sahu
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 14, Iss 8, Pp 350-358 (2024)
Objective: To evaluate the antimalarial activity of noscapine against Plasmodium falciparum 3D7 strain (Pf3D7), its clinical isolate (Pf140/SS), and Plasmodium berghei ANKA (PbA). Methods: Using ring-stage survival assay, phenotypic assessments, and
Externí odkaz:
https://doaj.org/article/0a6f21f5bb4d4356b5362a2383390550
Autor:
Yumei Li, Pei Ma, Jingxia Li, Feng Wu, Mengfei Guo, E Zhou, Siwei Song, Sufei Wang, Shuai Zhang, Yang Jin
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Background Immunosurveillance is pivotal in the effectiveness of anticancer therapies and tumor control. The ineffectiveness of cisplatin in activating the immunosurveillance is attributed to its lack of adjuvanticity resulting from its inab
Externí odkaz:
https://doaj.org/article/639b669043194550bcb040450c6a8dbf
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 5273-5295 (2024)
Bin Zheng,1– 3,* Fei Pan,1– 3,* Minfei Shi,1– 3 Cuiping He,1– 3 Beibei He,1– 3 Rongrong Wang,1– 3 Guolian Ren,1– 3 Shuang Yang,4 Shuqiu Zhang1– 3 1School of Pharmacy, Shanxi Medical University, Taiyuan, 030001, People’s Repu
Externí odkaz:
https://doaj.org/article/0cce6f13ccdc43e1955a2da0c5ae20e8
Autor:
Zhuoying Yang, Zehao Zhou, Qingyu Meng, Zhijie Chen, Liang Yun, Jianjun Jiang, Yujing He, Meijuan Dian, Ruihao Zhang, Haotian Ge, Tianbao Yan, Biying Men, Zichao Li, Xu Wu, Junming He, Shuan Rao
Publikováno v:
Cancer Medicine, Vol 13, Iss 19, Pp n/a-n/a (2024)
ABSTRACT Background Despite significant advances in lung cancer treatment, cisplatin (DDP)‐based chemotherapy remains a cornerstone for managing the disease. However, the prevalence of chemoresistance presents a major challenge, limiting its effect
Externí odkaz:
https://doaj.org/article/9f55a898b7354e5c83c603c94cd0e45d
Autor:
Peishan Qiu, Ying Chang, Xiaoyu Chen, Shaoqi Wang, Haihang Nie, Yuntian Hong, Meng Zhang, Haizhou Wang, Cong Xiao, Yuhua Chen, Lan Liu, Qiu Zhao
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract The precise mechanism underlying the therapeutic effects of dihydroartemisinin (DHA) in alleviating colitis remains incompletely understood. A strong correlation existed between the elevation of glial fibrillary acidic protein (GFAP)+/S100 c
Externí odkaz:
https://doaj.org/article/adcdae1f83494a27a489a2a6dd46b462
Autor:
Frederik Von Wowern, Geofrey Makenga, Sarah Wellmann Thomsen, Louise Wellmann Thomsen, Emma Filtenborg Hocke, Vito Baraka, Benjamin H. Opot, Daniel T.R. Minja, John P.A. Lusingu, Jean-Pierre Van-geertruyden, Helle Hansson, Michael Alifrangis
Publikováno v:
International Journal of Infectious Diseases, Vol 146, Iss , Pp 107102- (2024)
Objective: Intermittent Preventive Treatment of schoolchildren (IPTsc) is recommended by WHO as a strategy to protect against malaria; to explore whether IPTsc with dihydroartemisinin-piperaquine (DP) or artesunate-amodiaquine (ASAQ) cause a selectio
Externí odkaz:
https://doaj.org/article/abe4b30ff83545ca8a7b4b590155b130
Autor:
Liu-Gen Li, Xing-Chun Peng, Zi-Yi Yang, Ning Han, Chang-Long Gou, Jun Shi, Li-Li Yu, Nan-Nan Chen, Ting-Ting Yu, Tong-Fei Li, Xian-Yu Li, Jun Hu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Chemotherapeutic agents can inhibit the proliferation of malignant cells due to their cytotoxicity, which is limited by collateral damage. Dihydroartemisinin (DHA), has a selective anti-cancer effect, whose target and mechanism remain uncove
Externí odkaz:
https://doaj.org/article/cef8aa1158df444b860bcc60c3b7c2b1
Autor:
Ameyo Monique Dorkenoo, Marian Warsame, Essoham Ataba, Manani Hemou, Kossi Yakpa, Efoe Sossou, M’badi Mitigmsagou, Carmel Diwaba Teou, Emmanuelle Caspar, Laurence Ma, Koffi Edem Djadou, Tinah Atcha-Oubou, Charlotte Rasmussen, Didier Menard
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) are the currently recommended first- and second-line therapies for uncomplicated Plasmodium falciparum infections in Togo. This study assessed the efficacy of th
Externí odkaz:
https://doaj.org/article/84a2192568d44c24b6bbd91ca6b741bc