Morphine decreases cytotoxicity and mutagenicity of doxorubicin in vitro: Implications for cancer chemotherapy.

Autor: de Sousa JT; Laboratory of Genetic Toxicology, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil, Av. Farroupilha 8001, 92425-900, Canoas, RS, Brazil; Laboratory of Genetic Toxicity and Cellular Toxic-Genetic Analysis, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil, Av. Farroupilha 8001, 92425-900, Canoas, Brazil., Dihl RR; Laboratory of Genetic Toxicity and Cellular Toxic-Genetic Analysis, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil, Av. Farroupilha 8001, 92425-900, Canoas, Brazil., Menezes Boaretto FB; Laboratory of Genetic Toxicology, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil, Av. Farroupilha 8001, 92425-900, Canoas, RS, Brazil., Garcia ALH; Laboratory of Genetic Toxicology, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil, Av. Farroupilha 8001, 92425-900, Canoas, RS, Brazil; Laboratory of Genetics Toxicology, La Salle University, Av. Victor Barreto, 2288, 92010-000, Canoas, RS, Brazil., Grivicich I; Laboratory of Cancer Biology, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil, Av. Farroupilha 8001, 92425-900, Canoas, RS, Brazil., da Silva J; Laboratory of Genetic Toxicology, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil, Av. Farroupilha 8001, 92425-900, Canoas, RS, Brazil; Laboratory of Genetics Toxicology, La Salle University, Av. Victor Barreto, 2288, 92010-000, Canoas, RS, Brazil., Picada JN; Laboratory of Genetic Toxicology, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil, Av. Farroupilha 8001, 92425-900, Canoas, RS, Brazil. Electronic address: jaqueline.picada@ulbra.br.

Publikováno v: Chemico-biological interactions [Chem Biol Interact] 2023 Sep 01; Vol. 382, pp. 110652. Date of Electronic Publication: 2023 Jul 29.

Cyto-genotoxicity of crystalline and amorphous niobium (V) oxide nanoparticles in CHO-K1 cells.

Autor: Schardosim RFC; Laboratory of Genetic Toxicity and Cellular Toxic-Genetics Analysis, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil (ULBRA), Avenida Farroupilha, 8001, 92425-900, Canoas, RS, Brazil., Cardozo TR; Laboratory of Genetic Toxicity and Cellular Toxic-Genetics Analysis, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil (ULBRA), Avenida Farroupilha, 8001, 92425-900, Canoas, RS, Brazil.; Research Group on Nanostructured Materials, Federal University of the Pampa, Campus Bagé, Avenida Maria Anunciação Gomes de Godoy, 1650, 96413-172, RS, Brazil., de Souza AP; Laboratory of Genetic Toxicity and Cellular Toxic-Genetics Analysis, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil (ULBRA), Avenida Farroupilha, 8001, 92425-900, Canoas, RS, Brazil., Seeber A; Research Group on Nanostructured Materials, Federal University of the Pampa, Campus Bagé, Avenida Maria Anunciação Gomes de Godoy, 1650, 96413-172, RS, Brazil., Flores WH; Research Group on Nanostructured Materials, Federal University of the Pampa, Campus Bagé, Avenida Maria Anunciação Gomes de Godoy, 1650, 96413-172, RS, Brazil., Lehmann M; Laboratory of Genetic Toxicity and Cellular Toxic-Genetics Analysis, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil (ULBRA), Avenida Farroupilha, 8001, 92425-900, Canoas, RS, Brazil., Dihl RR; Laboratory of Genetic Toxicity and Cellular Toxic-Genetics Analysis, Graduate Program in Molecular and Cellular Biology Applied to Health, Lutheran University of Brazil (ULBRA), Avenida Farroupilha, 8001, 92425-900, Canoas, RS, Brazil.; Postgraduate Program in Dentistry, Lutheran University of Brazil (ULBRA), Avenida Farroupilha, 8001, 92425-900, Canoas, RS, Brazil.

Publikováno v: Toxicology research [Toxicol Res (Camb)] 2022 Aug 26; Vol. 11 (5), pp. 765-773. Date of Electronic Publication: 2022 Aug 26 (Print Publication: 2022).

Evaluation of the genetic toxicity of sofosbuvir and simeprevir with and without ribavirin in a human-derived liver cell line.

Autor: Librelotto CS; Programa de Pós-Graduação em Biologia Celular e Molecular Aplicada à Saúde, Universidade Luterana do Brasil (ULBRA), PPG Biologia Celular e Molecular Aplicada à Saúde, Av. Farroupilha, 8001, Prédio 22, 4° andar, 92425-900 Canoas, RS, Brazil., Souza AP; Programa de Pós-Graduação em Biologia Celular e Molecular Aplicada à Saúde, Universidade Luterana do Brasil (ULBRA), PPG Biologia Celular e Molecular Aplicada à Saúde, Av. Farroupilha, 8001, Prédio 22, 4° andar, 92425-900 Canoas, RS, Brazil., Álvares-DA-Silva MR; Programa de Pós-Graduação Ciências em Gastroenterologia e Hepatologia, Universidade Federal do Rio Grande do Sul (UFRGS), Hospital das Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Santa Cecilia, 90035-007 Porto Alegre, RS, Brazil., Simon D; Programa de Pós-Graduação em Biologia Celular e Molecular Aplicada à Saúde, Universidade Luterana do Brasil (ULBRA), PPG Biologia Celular e Molecular Aplicada à Saúde, Av. Farroupilha, 8001, Prédio 22, 4° andar, 92425-900 Canoas, RS, Brazil., Dihl RR; Programa de Pós-Graduação em Biologia Celular e Molecular Aplicada à Saúde, Universidade Luterana do Brasil (ULBRA), PPG Biologia Celular e Molecular Aplicada à Saúde, Av. Farroupilha, 8001, Prédio 22, 4° andar, 92425-900 Canoas, RS, Brazil.

Publikováno v: Anais da Academia Brasileira de Ciencias [An Acad Bras Cienc] 2021 Sep 24; Vol. 93 (4), pp. e20200632. Date of Electronic Publication: 2021 Sep 24 (Print Publication: 2021).

Evaluation of mutagenic activity of platinum complexes in somatic cells of Drosophila melanogaster.

Autor: Allgayer N; Laboratory of Genetic Toxicity (TOXIGEN), Graduate Program in Cellular and Molecular Biology Applied to Health (PPGBioSaúde), Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil., de Campos RA; Laboratory of Genetic Toxicity (TOXIGEN), Graduate Program in Cellular and Molecular Biology Applied to Health (PPGBioSaúde), Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil., Gonzalez LPF; Laboratory of Genetic Toxicity (TOXIGEN), Graduate Program in Cellular and Molecular Biology Applied to Health (PPGBioSaúde), Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil., Flores MDA; Laboratory of Genetic Toxicity (TOXIGEN), Graduate Program in Cellular and Molecular Biology Applied to Health (PPGBioSaúde), Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil., Dihl RR; Laboratory of Genetic Toxicity (TOXIGEN), Graduate Program in Cellular and Molecular Biology Applied to Health (PPGBioSaúde), Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil., Lehmann M; Laboratory of Genetic Toxicity (TOXIGEN), Graduate Program in Cellular and Molecular Biology Applied to Health (PPGBioSaúde), Lutheran University of Brazil (ULBRA), Canoas, RS, Brazil. Electronic address: mauriciol@ulbra.br.

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2019 Nov; Vol. 133, pp. 110782. Date of Electronic Publication: 2019 Aug 26.

Genotoxicity of zinc oxide nanoparticles: an in vivo and in silico study.

Autor: Cardozo TR; Laboratory of Genetic Toxicity , Graduate Program in Molecular and Cellular Biology Applied to Health , Lutheran University of Brazil (ULBRA) , Canoas , RS , Brazil . Email: rafael.rodrigues@ulbra.br ; ; Tel: + 55 51 34779219.; Federal University of Pampa - Research Group on Nanostructured Materials , Campus Bagé , RS , Brazil., De Carli RF; Laboratory of Genetic Toxicity , Graduate Program in Molecular and Cellular Biology Applied to Health , Lutheran University of Brazil (ULBRA) , Canoas , RS , Brazil . Email: rafael.rodrigues@ulbra.br ; ; Tel: + 55 51 34779219., Seeber A; Federal University of Pampa - Research Group on Nanostructured Materials , Campus Bagé , RS , Brazil., Flores WH; Federal University of Pampa - Research Group on Nanostructured Materials , Campus Bagé , RS , Brazil., da Rosa JAN; Laboratory of Genetic Toxicity , Graduate Program in Molecular and Cellular Biology Applied to Health , Lutheran University of Brazil (ULBRA) , Canoas , RS , Brazil . Email: rafael.rodrigues@ulbra.br ; ; Tel: + 55 51 34779219., Kotzal QSG; Laboratory of Genetic Toxicity , Graduate Program in Molecular and Cellular Biology Applied to Health , Lutheran University of Brazil (ULBRA) , Canoas , RS , Brazil . Email: rafael.rodrigues@ulbra.br ; ; Tel: + 55 51 34779219., Lehmann M; Laboratory of Genetic Toxicity , Graduate Program in Molecular and Cellular Biology Applied to Health , Lutheran University of Brazil (ULBRA) , Canoas , RS , Brazil . Email: rafael.rodrigues@ulbra.br ; ; Tel: + 55 51 34779219., da Silva FR; La Salle University , Master's Degree in Environmental Impact Evaluation , Canoas , RS , Brazil., Dihl RR; Laboratory of Genetic Toxicity , Graduate Program in Molecular and Cellular Biology Applied to Health , Lutheran University of Brazil (ULBRA) , Canoas , RS , Brazil . Email: rafael.rodrigues@ulbra.br ; ; Tel: + 55 51 34779219.

Publikováno v: Toxicology research [Toxicol Res (Camb)] 2019 Jan 30; Vol. 8 (2), pp. 277-286. Date of Electronic Publication: 2019 Jan 30 (Print Publication: 2019).