Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Dihexa"'
1
Akademický článek
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2
Akademický článek
AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway
Autor: Xiaojin Sun, Yang Deng, Xinxin Fu, Siyu Wang, Rui Duan, Yingdong Zhang
Publikováno v: Brain Sciences, Vol 11, Iss 11, p 1487 (2021)
The renin-angiotensin system (RAS) is a paracrine RAS within the central nervous system (CNS) and is closely related to Alzheimer’s disease (AD). The endogenous hexapeptide angiotensin IV (Ang IV), an important component of the brain RAS, was found
Externí odkaz: https://doaj.org/article/fa0b1a5489b741a98e156e1bda147186
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3
AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway
Autor: Si-Yu Wang, Rui Duan, Ying‐Dong Zhang, Yang Deng, Xiaojin Sun, Xinxin Fu
Publikováno v: Brain Sciences, Vol 11, Iss 1487, p 1487 (2021)
Brain Sciences
Volume 11
Issue 11
The renin-angiotensin system (RAS) is a paracrine RAS within the central nervous system (CNS) and is closely related to Alzheimer’s disease (AD). The endogenous hexapeptide angiotensin IV (Ang IV), an important component of the brain RAS, was found
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccebfed79e86715741190fb71bee3a9a
https://www.mdpi.com/2076-3425/11/11/1487
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4
Stem cell, Granulocyte-Colony Stimulating Factor and/or Dihexa to promote limb function recovery in a rat sciatic nerve damage-repair model: Experimental animal studies
Autor: Edward W. Malin, Shashikumar Salgar, Cody J. Phillips, Vijay S. Gorantla, Jessica B. Weiss, Joseph W. Harding
Publikováno v: Annals of Medicine and Surgery
Background Optimizing nerve regeneration and re-innervation of target muscle/s is the key for improved functional recovery following peripheral nerve damage. We investigated whether administration of mesenchymal stem cell (MSC), Granulocyte-Colony St
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdbb347c3f04e339e8405bec43edf6f
http://europepmc.org/articles/PMC8524106
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5
Akademický článek
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6
Akademický článek
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7
Cognitive benefits of angiotensin IV and angiotensin-(1-7): A systematic review of experimental studies
Autor: Jean K. Ho, Daniel A. Nation
Publikováno v: Neurosci Biobehav Rev
Objectives To explore effects of the brain renin-angiotensin system (RAS) on cognition. Design Systematic review of experimental (non-human) studies assessing cognitive effects of RAS peptides angiotensin-(3–8) [Ang IV] and angiotensin-(1–7) [Ang
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cf608983e0512474e6f022a376e551
https://pubmed.ncbi.nlm.nih.gov/29733881
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8
The Brain Hepatocyte Growth Factor/c-Met Receptor System: A New Target for the Treatment of Alzheimer's Disease
Autor: Joseph W. Harding, John W. Wright
Publikováno v: Journal of Alzheimer's Disease. 45:985-1000
Alzheimer's disease (AD) is a progressive neurodegenerative disease increasing in frequency as life expectancy of the world's population increases. There are an estimated 5 million diagnosed AD patients in the U.S. and 16 million worldwide with no ad
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8c2ad3225f36763e68392b774832ab
https://doi.org/10.3233/jad-142814
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9
The development of small molecule angiotensin IV analogs to treat Alzheimer's and Parkinson's diseases
Autor: Leen H. Kawas, Joseph W. Harding, John W. Wright
Publikováno v: Progress in Neurobiology. 125:26-46
Alzheimer's (AD) and Parkinson's (PD) diseases are neurodegenerative diseases presently without effective drug treatments. AD is characterized by general cognitive impairment, difficulties with memory consolidation and retrieval, and with advanced st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d53a9b22372676baa4b01bc38206f3
https://doi.org/10.1016/j.pneurobio.2014.11.004
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10
Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive/Antidementia Agents
Autor: Suzanne M. Appleyard, Alene T. McCoy, Gary A. Wayman, John W. Wright, Mingyan Zhu, Caroline C. Benoist, Joseph W. Harding, Leen H. Kawas, Jyote M. Bule-Ghogare
Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 344:141-154
Angiotensin IV (AngIV: VYIHPF)-related peptides have long been recognized as procognitive agents with potential as antidementia therapeutics. Their development as useful therapeutics, however, has been limited by physiochemical properties that make t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97bb80f8919ad780c8f2da573faecbd0
https://doi.org/10.1124/jpet.112.199497
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