Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Diggory Hardy"'
Publikováno v:
Evolutionary Applications, Vol 13, Iss 10, Pp 2723-2739 (2020)
Abstract Introduction Control strategies for human infections are often investigated using individual‐based models (IBMs) to quantify their impact in terms of mortality, morbidity and impact on transmission. Genetic selection can be incorporated in
Externí odkaz:
https://doaj.org/article/0014163d815c447aa04c6b5d4912bbf3
Simulated impact of RTS,S/AS01 vaccination programs in the context of changing malaria transmission.
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32587 (2012)
INTRODUCTION: The RTS,S/AS01 pre-erythrocytic malaria vaccine is in phase III clinical trials. It is critical to anticipate where and how it should be implemented if trials are successful. Such planning may be complicated by changing levels of malari
Externí odkaz:
https://doaj.org/article/f64c312bcba9470699fe2f397b2f06f9
Autor:
Thomas Smith, Amanda Ross, Nicolas Maire, Nakul Chitnis, Alain Studer, Diggory Hardy, Alan Brooks, Melissa Penny, Marcel Tanner
Publikováno v:
PLoS Medicine, Vol 9, Iss 1, p e1001157 (2012)
BACKGROUND: The RTS,S malaria vaccine may soon be licensed. Models of impact of such vaccines have mainly considered deployment via the World Health Organization's Expanded Programme on Immunization (EPI) in areas of stable endemic transmission of Pl
Externí odkaz:
https://doaj.org/article/2764aef221574b3a938b1cc0480d7816
Publikováno v:
Bulletin of Mathematical Biology
We describe and analyze a periodically-forced difference equation model for malaria in mosquitoes that captures the effects of seasonality and allows the mosquitoes to feed on a heterogeneous population of hosts. We numerically show the existence of
Autor:
Roch K. Dabiré, Olivier J T Briët, Nakul Chitnis, Vincent Corbel, Wim Van Bortel, Benjamin G. Koudou, T. S. Awolola, Diggory Hardy, Josiane Etang, Melissa A. Penny, Patrick K. Tungu
Publikováno v:
Malaria Journal
BACKGROUND\ud \ud The effectiveness of insecticide-treated nets in preventing malaria is threatened by developing resistance against pyrethroids. Little is known about how strongly this affects the effectiveness of vector control programmes.\ud \ud M
Autor:
Jennifer C Stevenson, Mary Cooke, Nakul Chitnis, Elizabeth Marube, Thomas J. Smith, Chris Drakeley, Jonathan Cox, Chrispin Owaga, Diggory Hardy, George Oando, Erin M. Stuckey
Publikováno v:
Malaria Journal
Malaria Journal, Vol 11, Iss 1, p 357 (2012)
Malaria Journal, Vol 11, Iss 1, p 357 (2012)
Background Models of Plasmodium falciparum malaria epidemiology that provide realistic quantitative predictions of likely epidemiological outcomes of existing vector control strategies have the potential to assist in planning for the control and elim
Publikováno v:
Malaria Journal
Malaria Journal, Vol 11, Iss 1, p 20 (2012)
Malaria Journal, Vol 11, Iss 1, p 20 (2012)
Background Long-lasting insecticidal nets (LLINs) reduce malaria transmission by protecting individuals from infectious bites, and by reducing mosquito survival. In recent years, millions of LLINs have been distributed across sub-Saharan Africa (SSA)
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32587 (2012)
PLoS ONE
PLoS ONE
INTRODUCTION: The RTS,S/AS01 pre-erythrocytic malaria vaccine is in phase III clinical trials. It is critical to anticipate where and how it should be implemented if trials are successful. Such planning may be complicated by changing levels of malari
Autor:
Alan Brooks, Nicolas Maire, Thomas J. Smith, Alain Studer, Nakul Chitnis, Amanda Ross, Diggory Hardy, Marcel Tanner, Melissa A. Penny
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 9, Iss 1, p e1001157 (2012)
PLoS Medicine, Vol 9, Iss 1, p e1001157 (2012)
Using an ensemble modeling approach, Thomas Smith and colleagues find that targeted mass vaccination with a pre-erythrocytic malaria vaccine RTS,S in low-transmission settings might have better health effects than vaccination through national EPI pro
Autor:
Valerie Crowell, Nakul Chitnis, Olivier J T Briët, Diggory Hardy, Thomas J. Smith, Nicolas Maire
Publikováno v:
Epidemics. 4(1)
Recent declines in malaria burden in many parts of the world have prompted consideration of how interruption of Plasmodium falciparum transmission could be maintained, if achieved, and notably whether large-scale vector control could be replaced with