Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Digby F, Warner"'
Autor:
Nosipho Cele, Paul Awolade, Pule Seboletswe, Lungisani Khubone, Kolawole Olofinsan, Md. Shahidul Islam, Audrey Jordaan, Digby F. Warner, Parvesh Singh
Publikováno v:
ChemistryOpen, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract Two libraries of quinoline‐based hybrids 1‐(7‐chloroquinolin‐4‐yl)‐1H‐pyrazolo[3,4–d]pyrimidin‐4‐amine and 7‐chloro‐N‐phenylquinolin‐4‐amine were synthesized and evaluated for their α‐glucosidase inhibitory a
Externí odkaz:
https://doaj.org/article/8d47b8ac9082410195c81e8781270c6f
Autor:
Ryan Dinkele, Sophia Gessner, Benjamin Patterson, Andrea McKerry, Zeenat Hoosen, Andiswa Vazi, Ronnett Seldon, Anastasia Koch, Digby F. Warner, Robin Wood
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110731- (2024)
Summary: Pioneering studies linking symptomatic disease and cough-mediated Mycobacterium tuberculosis (Mtb) release established the infectious origin of tuberculosis (TB), simultaneously informing the notion that pathology is a prerequisite for Mtb t
Externí odkaz:
https://doaj.org/article/da923caae79242cdad598fe4156b4b12
Autor:
Melissa D. Chengalroyen, Carolina Mehaffy, Megan Lucas, Niel Bauer, Mabule L. Raphela, Nurudeen Oketade, Digby F. Warner, Deborah A. Lewinsohn, David M. Lewinsohn, Karen M. Dobos, Valerie Mizrahi
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Riboflavin (vitamin B2) is the precursor of the flavin coenzymes, FAD and FMN, which play a central role in cellular redox metabolism. While humans must obtain riboflavin from dietary sources, certain microbes, including Mycobacterium tuberc
Externí odkaz:
https://doaj.org/article/9e0d64474c2449c7bd3876da27d5decc
Autor:
Phelelisiwe S. Dube, Dylan Hart, Lesetja J. Legoabe, Audrey Jordaan, Digby F. Warner, Richard M. Beteck
Publikováno v:
Molbank, Vol 2024, Iss 1, p M1793 (2024)
Nitrothiazole derivatives have been reported to exhibit activity against aerobic, anaerobic, and microaerophilic bacteria. This activity profile makes the nitrothiazole compound class an ideal lead source against Mycobacterium tuberculosis, which flo
Externí odkaz:
https://doaj.org/article/40c7ba286eb94060a2d26e116b07e4f3
Autor:
Sophia Gessner, Zela Alexandria-Mae Martin, Michael A Reiche, Joana A Santos, Ryan Dinkele, Atondaho Ramudzuli, Neeraj Dhar, Timothy J de Wet, Saber Anoosheh, Dirk M Lang, Jesse Aaron, Teng-Leong Chew, Jennifer Herrmann, Rolf Müller, John D McKinney, Roger Woodgate, Valerie Mizrahi, Česlovas Venclovas, Meindert H Lamers, Digby F Warner
Publikováno v:
eLife, Vol 12 (2023)
A DNA damage-inducible mutagenic gene cassette has been implicated in the emergence of drug resistance in Mycobacterium tuberculosis during anti-tuberculosis (TB) chemotherapy. However, the molecular composition and operation of the encoded ‘mycoba
Externí odkaz:
https://doaj.org/article/9340d5204dad4cac96d701c78d904d63
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/3a63025ee6ea49868a9ca5c37f89362c
Autor:
Dapeng Chen, Noella A. Bryden, Wayne A. Bryden, Michael McLoughlin, Dexter Smith, Alese P. Devin, Emily R. Caton, Caroline R. Haddaway, Michele Tameris, Thomas J. Scriba, Mark Hatherill, Sophia Gessner, Digby F. Warner, Robin Wood
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Human breath contains trace amounts of non-volatile organic compounds (NOCs) which might provide non-invasive methods for evaluating individual health. In previous work, we demonstrated that lipids detected in exhaled breath aerosol (EBA) co
Externí odkaz:
https://doaj.org/article/b86a92237e754997bbf460bc5655d54d
Autor:
Digby F. Warner, Robin Wood
Publikováno v:
Journal of the International AIDS Society, Vol 26, Iss 3, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/0445dd1074124102bb4233d0451e3c9a
Autor:
Emmanuel T. Oluwabusola, Olusoji O. Adebisi, Fernando Reyes, Kojo S. Acquah, Mercedes De La Cruz, Larry L. Mweetwa, Joy E. Rajakulendran, Digby F. Warner, Deng Hai, Rainer Ebel, Marcel Jaspars
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 2390-2398 (2021)
Five new phenolic siderophores 1–5 were isolated from the organic extract of a culture broth in a modified SGG medium of Pseudomonas sp. UIAU-6B, obtained from sediments collected from the Oyun river in North Central Nigeria. The structure of the n
Externí odkaz:
https://doaj.org/article/ac943a8fb0014749afe652c4e4f8b060
Autor:
David A. Barr, Charles Omollo, Mandy Mason, Anastasia Koch, Robert J. Wilkinson, David G. Lalloo, Graeme Meintjes, Valerie Mizrahi, Digby F. Warner, Gerry Davies
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Detection and accurate quantitation of viable Mycobacterium tuberculosis is fundamental to understanding mycobacterial pathogenicity, tuberculosis (TB) disease progression and outcomes; TB transmission; drug action, efficacy and drug resista
Externí odkaz:
https://doaj.org/article/74eeee5f5254448cad1a301799e30ef2