Zobrazeno 1 - 10
of 760
pro vyhledávání: '"Differential Methylation"'
Autor:
Trent Newman, Donna M. Bond, Teruhito Ishihara, Phoebe Rizzoli, Quentin Gouil, Timothy A. Hore, Geoff Shaw, Marilyn B. Renfree
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-21 (2024)
Abstract Background Genomic imprinting results in parent-of-origin-specific gene expression and, among vertebrates, is found only in therian mammals: marsupials and eutherians. A differentially methylated region (DMR), in which the methylation status
Externí odkaz:
https://doaj.org/article/061d1a17d2ae438787b7cc04888fca66
Autor:
Adrián López-Catalina, Antonio Reverter, Pamela A. Alexandre, Loan T. Nguyen, Oscar González-Recio
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Epigenetic marks do not follow the Mendelian laws of inheritance. The environment can alter the epigenotype of an individual when exposed to different external stressors. In lactating cows, the first stages of gestation overlap with the lactation pea
Externí odkaz:
https://doaj.org/article/0489d703b0d3459b8f92cd2a7b168752
Autor:
Stefania Palumbo, Domenico Palumbo, Grazia Cirillo, Giorgio Giurato, Francesca Aiello, Emanuele Miraglia del Giudice, Anna Grandone
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Genetic and environmental factors are implicated in many developmental processes. Recent evidence, however, has suggested that epigenetic changes may also influence the onset of puberty or the susceptibility to a wide range of dis
Externí odkaz:
https://doaj.org/article/c0475ce76cd14798b72a48f0443ad05d
Autor:
Yongwei Jiang, GuoXiong Deng, Chengyin Liu, Han Tang, Jing Zheng, Xiaomu Kong, Meimei Zhao, Yi Liu, Peng Gao, Tianbao Li, Hailing Zhao, Yongtong Cao, Ping Li, Liang Ma
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background The objective of this study was to examine and analyze differential methylation profiles in order to investigate the influence of hyper-methioninemia (HM) on the development of diabetic nephropathy (DN). Male Wistar rats, aged eig
Externí odkaz:
https://doaj.org/article/94bfd5649024458a81592fcc774f2dd3
Autor:
Przemyslaw Szafranski, Rijutha P. Garimella, Haresh Mani, Ryan Hartman, Gail Deutsch, Alan Silk, Alan Benheim, Paweł Stankiewicz
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-6 (2023)
Abstract Heterozygous SNVs or CNV deletions involving the FOXF1 gene, or its distant enhancer, are causative for 80–90% of cases of alveolar capillary dysplasia with misalignment of pulmonary veins. Recently, we proposed bimodal structure and paren
Externí odkaz:
https://doaj.org/article/f586cec64f4549ceaf3bf3d1ae46ce56
Autor:
Jiawen Zhao, Chujun Zhang, Sifan Li, Mengmeng Yuan, Wenlan Mu, Jing Yang, Yutong Ma, Cuiping Guan, Chuang Ma
Publikováno v:
BMC Plant Biology, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background N 6-methyladenosine (m6A) modification is the most abundant type of RNA modification in eukaryotic cells, playing pivotal roles in multiple plant growth and development processes. Yet the potential role of m6A in conferring the tr
Externí odkaz:
https://doaj.org/article/1c126cdeead945dfb8f5f1ee782f0dda
Autor:
Essi Laajala, Viivi Halla-aho, Toni Grönroos, Ubaid Ullah Kalim, Mari Vähä-Mäkilä, Mirja Nurmio, Henna Kallionpää, Niina Lietzén, Juha Mykkänen, Omid Rasool, Jorma Toppari, Matej Orešič, Mikael Knip, Riikka Lund, Riitta Lahesmaa, Harri Lähdesmäki
Publikováno v:
Epigenetics, Vol 17, Iss 12, Pp 1608-1627 (2022)
DNA methylation patterns are largely established in-utero and might mediate the impacts of in-utero conditions on later health outcomes. Associations between perinatal DNA methylation marks and pregnancy-related variables, such as maternal age and ge
Externí odkaz:
https://doaj.org/article/667134eacf774c6e931b0432d4c2ea31
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract ST08 and ST09 are potent curcumin derivatives with antiproliferative, apoptotic, and migrastatic properties. Both ST08 and ST09 exhibit in vitro and in vivo anticancer properties. As reported earlier, these derivatives were highly cytotoxic
Externí odkaz:
https://doaj.org/article/3c30a4e35f3b4668a0ab542bf4d6255d
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