Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma.

Autor: Afaq F; Department of Pathology, University of Alabama at Birmingham, USA., Agarwal S; Department of Pathology, University of Alabama at Birmingham, USA., Bajpai P; Department of Pathology, University of Alabama at Birmingham, USA., Diffalha SA; Department of Pathology, University of Alabama at Birmingham, USA; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, USA., Kim HG; Department of Pathology, University of Alabama at Birmingham, USA., Peter S; Department of Medicine, Division of Gastroenterology, University of Alabama at Birmingham, USA., Khushman M; Department of Medicine, Division of Medical Oncology, Washington University in St. Louis, USA., Chauhan SC; Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley, USA., Mukherjee P; Department of Pathology, the University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Varambally S; Department of Pathology, University of Alabama at Birmingham, USA; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, USA., Manne U; Department of Pathology, University of Alabama at Birmingham, USA; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, USA. Electronic address: upendermanne@uabmc.edu.

Publikováno v: Neoplasia (New York, N.Y.) [Neoplasia] 2024 Jan; Vol. 47, pp. 100951. Date of Electronic Publication: 2023 Nov 30.

Molecular characterization of visible low-grade dysplastic lesions in patients with inflammatory bowel disease.

Autor: Dhall D; Department of Pathology, University of Alabama at Birmingham, AL, 35249, USA. Electronic address: ddhall@uabmc.edu., Makhoul E; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Taguibao R; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Waters K; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Zhang W; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Vail E; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Lee G; Department of Pathology, University of Alabama at Birmingham, AL, 35249, USA., Diffalha SA; Department of Pathology, University of Alabama at Birmingham, AL, 35249, USA., Patel C; Department of Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA., Manne U; Department of Pathology, University of Alabama at Birmingham, AL, 35249, USA., Behring M; Department of Pathology, University of Alabama at Birmingham, AL, 35249, USA; Department of Health Sciences, Athens State University, Athens, AL, 35611, USA., Chopra S; Department of Pathology, University of Southern California, Los Angeles, 90033, USA., Harada S; Department of Pathology, University of Alabama at Birmingham, AL, 35249, USA.

Publikováno v: Human pathology [Hum Pathol] 2023 May; Vol. 135, pp. 108-116. Date of Electronic Publication: 2023 Feb 06.

DCZ0415, a small-molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β-catenin pathway in colorectal cancer.

Autor: Agarwal S; Department of Pathology, University of Alabama at Birmingham, AL, USA., Afaq F; Department of Pathology, University of Alabama at Birmingham, AL, USA., Bajpai P; Department of Pathology, University of Alabama at Birmingham, AL, USA., Kim HG; Department of Pathology, University of Alabama at Birmingham, AL, USA., Elkholy A; Department of Pathology, University of Alabama at Birmingham, AL, USA., Behring M; Department of Pathology, University of Alabama at Birmingham, AL, USA., Chandrashekar DS; Department of Pathology, University of Alabama at Birmingham, AL, USA., Diffalha SA; Department of Pathology, University of Alabama at Birmingham, AL, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, AL, USA., Khushman M; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, AL, USA.; Department of Medicine, Division of Medical Oncology, University of Alabama at Birmingham, AL, USA., Sugandha SP; Department of Medicine, Division of Gastroenterology, University of Alabama at Birmingham, AL, USA., Varambally S; Department of Pathology, University of Alabama at Birmingham, AL, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, AL, USA., Manne U; Department of Pathology, University of Alabama at Birmingham, AL, USA.; O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, AL, USA.

Publikováno v: Molecular oncology [Mol Oncol] 2022 Apr; Vol. 16 (8), pp. 1728-1745. Date of Electronic Publication: 2022 Mar 07.

Expression of MHC class I polypeptide-related sequence A (MICA) in colorectal cancer.

Autor: Espinoza I; Department of Preventive Medicine, John D. Bower School of Population Health, University of Mississippi Medical Center, Jackson, MS 39216, USA.; Center for Clinical and Translational Science (CCTS), University of Mississippi School of Pharmacy (UMSOP) & University of Mississippi Medical Center, Jackson, MS 39216, USA.; Cancer Center and Research Institute, University of Mississippi Medical Center, Jackson, MS 39216, USA., Agarwal S; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Sakiyama M; Department of Pathology, University of Mississippi Medical Center, Jackson, MS 39216, USA.; CAPES Foundation, Ministry of Education of Brazil, Esplanada dos Ministerios, 70000 Brasilia, Brazil., Shenoy V; Department of Pathology, University of Mississippi Medical Center, Jackson, MS 39216, USA., Orr WS; Department of Transplant/Hepatobiliary Surgery, University of Mississippi Medical Center, Jackson, MS 39216, USA., Diffalha SA; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; O'Neal Comprehensive Cancer Center University of Alabama at Birmingham, Birmingham, AL 35294, USA., Prizment A; Division of Hematology, Oncology and Transplantation, Medical School, University of Minnesota, Minneapolis, MN 55455, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Varambally S; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; O'Neal Comprehensive Cancer Center University of Alabama at Birmingham, Birmingham, AL 35294, USA., Manne U; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; O'Neal Comprehensive Cancer Center University of Alabama at Birmingham, Birmingham, AL 35294, USA., Gomez CR; Center for Clinical and Translational Science (CCTS), University of Mississippi School of Pharmacy (UMSOP) & University of Mississippi Medical Center, Jackson, MS 39216, USA.; Department of Pathology, University of Mississippi Medical Center, Jackson, MS 39216, USA.; Department of Radiation Oncology, University of Mississippi Medical Center, Jackson, MS 39216, USA.

Publikováno v: Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2021 Oct 30; Vol. 26 (10), pp. 765-776.

Gastric Sclerosing Epithelioid Fibrosarcoma Harboring a Rare FUS - CREM Fusion.

Autor: Memon RA; Depatment of Pathology, University of Alabama at Birmingham, Birmingham AL, USA., Granada CNP; Depatment of Pathology, University of Alabama at Birmingham, Birmingham AL, USA., Patel C; Depatment of Pathology, University of Alabama at Birmingham, Birmingham AL, USA., Manne U; Depatment of Pathology, University of Alabama at Birmingham, Birmingham AL, USA., Heslin MJ; Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA., Gbolahan OB; Department of Medicine/Hematology & Oncology, University of Alabama at Birmingham, AL, USA., Harada S; Depatment of Pathology, University of Alabama at Birmingham, Birmingham AL, USA., Diffalha SA; Depatment of Pathology, University of Alabama at Birmingham, Birmingham AL, USA.

Publikováno v: International journal of surgical pathology [Int J Surg Pathol] 2021 Aug; Vol. 29 (5), pp. 565-570. Date of Electronic Publication: 2020 Sep 23.