MV140 Mucosal Vaccine Induces Targeted Immune Response for Enhanced Clearance of Uropathogenic E. coli in Experimental Urinary Tract Infection.

Autor: Saz-Leal P; Inmunotek S.L., 28805 Madrid, Spain.; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO 63110, USA., Ligon MM; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO 63110, USA., Diez-Rivero CM; Inmunotek S.L., 28805 Madrid, Spain., García-Ayuso D; Inmunotek S.L., 28805 Madrid, Spain., Mohanty S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.; Division of Clinical Microbiology, Karolinska University Hospital, 17176 Stockholm, Sweden., Viñuela M; Inmunotek S.L., 28805 Madrid, Spain., Real-Arévalo I; Inmunotek S.L., 28805 Madrid, Spain., Conejero L; Inmunotek S.L., 28805 Madrid, Spain., Brauner A; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden.; Division of Clinical Microbiology, Karolinska University Hospital, 17176 Stockholm, Sweden., Subiza JL; Inmunotek S.L., 28805 Madrid, Spain., Mysorekar IU; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.

Publikováno v: Vaccines [Vaccines (Basel)] 2024 May 14; Vol. 12 (5). Date of Electronic Publication: 2024 May 14.

MV140 mucosal bacterial vaccine improves uropathogenic E. coli clearance in an experimental model of urinary tract infection.

Autor: Saz-Leal P; Inmunotek, S.L. Alcalá de Henares, Madrid, Spain.; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA., Ligon MM; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA., Diez-Rivero CM; Inmunotek, S.L. Alcalá de Henares, Madrid, Spain., García-Ayuso D; Inmunotek, S.L. Alcalá de Henares, Madrid, Spain., Mohanty S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.; Division of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden., Conejero L; Inmunotek, S.L. Alcalá de Henares, Madrid, Spain., Brauner A; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.; Division of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden., Subiza JL; Inmunotek, S.L. Alcalá de Henares, Madrid, Spain., Mysorekar IU; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX.; Department of Molecular Virology and Microbiology, Baylor College of Medicine.

Publikováno v: Research square [Res Sq] 2023 Jun 07. Date of Electronic Publication: 2023 Jun 07.

A Combination of Polybacterial MV140 and Candida albicans V132 as a Potential Novel Trained Immunity-Based Vaccine for Genitourinary Tract Infections.

Autor: Martin-Cruz L; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain., Sevilla-Ortega C; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain., Benito-Villalvilla C; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain., Diez-Rivero CM; Inmunotek, Alcalá de Henares, Madrid, Spain., Sanchez-Ramón S; Department of Clinical Immunology and IdISSC, Hospital Clínico San Carlos, Madrid, Spain.; Department of Immunology, ENT and Ophthalmology, School of Medicine, Complutense University, Madrid, Spain., Subiza JL; Inmunotek, Alcalá de Henares, Madrid, Spain., Palomares O; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Jan 21; Vol. 11, pp. 612269. Date of Electronic Publication: 2021 Jan 21 (Print Publication: 2020).

Human dendritic cells activated with MV130 induce Th1, Th17 and IL-10 responses via RIPK2 and MyD88 signalling pathways.

Autor: Cirauqui C; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain., Benito-Villalvilla C; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain., Sánchez-Ramón S; Department of Immunology, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, Spain.; Dpt. of Microbiology I-Immunology, School of Medicine, Complutense University of Madrid, Madrid, Spain., Sirvent S; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain., Diez-Rivero CM; Inmunotek S.L., Madrid, Spain., Conejero L; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain., Brandi P; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain., Hernández-Cillero L; Department of Immunology, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, Spain.; Genomics and Microarray Laboratory, Department of Medical Oncology, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, Spain., Ochoa JL; Department of Immunology, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, Spain., Pérez-Villamil B; Genomics and Microarray Laboratory, Department of Medical Oncology, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, Spain., Sancho D; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain., Subiza JL; Department of Immunology, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, Spain.; Dpt. of Microbiology I-Immunology, School of Medicine, Complutense University of Madrid, Madrid, Spain.; Inmunotek S.L., Madrid, Spain., Palomares O; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain.

Publikováno v: European journal of immunology [Eur J Immunol] 2018 Jan; Vol. 48 (1), pp. 180-193. Date of Electronic Publication: 2017 Sep 14.

Novel vaccines targeting dendritic cells by coupling allergoids to nonoxidized mannan enhance allergen uptake and induce functional regulatory T cells through programmed death ligand 1.

Autor: Sirvent S; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain., Soria I; Inmunotek, Alcalá de Henares, Spain; Department of Immunology, Hospital Clínico San Carlos, Madrid, Spain., Cirauqui C; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain., Cases B; Inmunotek, Alcalá de Henares, Spain., Manzano AI; Centro de Investigaciones Biológicas, Madrid, Spain., Diez-Rivero CM; Department of Microbiology I-Immunology, School of Medicine, Complutense University of Madrid, Madrid, Spain., Reche PA; Department of Microbiology I-Immunology, School of Medicine, Complutense University of Madrid, Madrid, Spain., López-Relaño J; Department of Microbiology I-Immunology, School of Medicine, Complutense University of Madrid, Madrid, Spain., Martínez-Naves E; Department of Microbiology I-Immunology, School of Medicine, Complutense University of Madrid, Madrid, Spain., Cañada FJ; Centro de Investigaciones Biológicas, Madrid, Spain., Jiménez-Barbero J; Centro de Investigaciones Biológicas, Madrid, Spain; CIC bioGUNE, Parque Tecnológico de Bizkaia, Bilbao, Spain., Subiza J; Clínica Subiza S.A., Madrid, Spain., Casanovas M; Inmunotek, Alcalá de Henares, Spain., Fernández-Caldas E; Inmunotek, Alcalá de Henares, Spain; University of South Florida, College of Medicine, Tampa, Fla., Subiza JL; Inmunotek, Alcalá de Henares, Spain; Department of Immunology, Hospital Clínico San Carlos, Madrid, Spain; Department of Microbiology I-Immunology, School of Medicine, Complutense University of Madrid, Madrid, Spain., Palomares O; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University, Madrid, Spain. Electronic address: oscar.palomares@quim.ucm.es.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2016 Aug; Vol. 138 (2), pp. 558-567.e11. Date of Electronic Publication: 2016 Apr 13.