Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Diewertje I. Bink"'
Autor:
Noelia Lozano-Vidal, Laura Stanicek, Diewertje I. Bink, Rio P. Juni, Aukie Hooglugt, Veerle Kremer, Philippa Phelp, Anke van Bergen, Alyson W. MacInnes, Stefanie Dimmeler, Reinier A. Boon
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Age-related diseases pose great challenges to health care systems worldwide. During aging, endothelial senescence increases the risk for cardiovascular disease. Recently, it was described that Phosphatase 1 Nuclear Targeting Subunit (PNUTS)
Externí odkaz:
https://doaj.org/article/c23b2adb9f504a019c2402bcb783687d
Autor:
Veerle Kremer, Diewertje I. Bink, Laura Stanicek, Eva van Ingen, Theresa Gimbel, Sarah Hilderink, Stefan Günther, Anne Yaël Nossent, Reinier A. Boon
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract A large portion of the genome is transcribed into non-coding RNA, which does not encode protein. Many long non-coding RNAs (lncRNAs) have been shown to be involved in important regulatory processes such as genomic imprinting and chromatin mo
Externí odkaz:
https://doaj.org/article/3bc5639ebbcb4d0fa042463c3214f86d
Autor:
D. Julia Trembinski, Diewertje I. Bink, Kosta Theodorou, Janina Sommer, Ariane Fischer, Anke van Bergen, Chao-Chung Kuo, Ivan G. Costa, Christoph Schürmann, Matthias S. Leisegang, Ralf P. Brandes, Tijna Alekseeva, Boris Brill, Astrid Wietelmann, Christopher N. Johnson, Alexander Spring-Connell, Manuel Kaulich, Stanislas Werfel, Stefan Engelhardt, Marc N. Hirt, Kaja Yorgan, Thomas Eschenhagen, Luisa Kirchhof, Patrick Hofmann, Nicolas Jaé, Ilka Wittig, Nazha Hamdani, Corinne Bischof, Jaya Krishnan, Riekelt H. Houtkooper, Stefanie Dimmeler, Reinier A. Boon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Aging induces cardiovascular disease, but which RNA molecules control cardiac aging is poorly understood. Here the authors identified the aging-regulated non-coding RNA Sarrah, which controls cardiomyocyte survival and cardiac function by inducing ca
Externí odkaz:
https://doaj.org/article/7441973a82494a94a2d3de6efa08b38c
Long Non-coding RNA Aerrie Controls DNA Damage Repair via YBX1 to Maintain Endothelial Cell Function
Autor:
Tan Phát Pham, Diewertje I. Bink, Laura Stanicek, Anke van Bergen, Esmee van Leeuwen, Yvonne Tran, Ljubica Matic, Ulf Hedin, Ilka Wittig, Stefanie Dimmeler, Reinier A. Boon
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Aging is accompanied by many physiological changes. These changes can progressively lead to many types of cardiovascular diseases. During this process blood vessels lose their ability to maintain vascular homeostasis, ultimately resulting in hyperten
Externí odkaz:
https://doaj.org/article/db173c12137e46d19996572b2e0787ab
Publikováno v:
Non-Coding RNA, Vol 5, Iss 1, p 26 (2019)
Cardiovascular diseases are the most prominent cause of death in Western society, especially in the elderly. With the increasing life expectancy, the number of patients with cardiovascular diseases will rise in the near future, leading to an increase
Externí odkaz:
https://doaj.org/article/4b006b6a8d3a45a4a0b41e279783370b
Publikováno v:
Bink, D I, Pauli, J, Maegdefessel, L & Boon, R A 2023, ' Endothelial microRNAs and long noncoding RNAs in cardiovascular ageing ', Atherosclerosis, vol. 374, pp. 99-106 . https://doi.org/10.1016/j.atherosclerosis.2023.03.019
Atherosclerosis and numerous other cardiovascular diseases develop in an age-dependent manner. The endothelial cells that line the vessel walls play an important role in the development of atherosclerosis. Non-coding RNA like microRNAs and long non-c
Autor:
Reinier A Boon, Sarah Hilderink, Eva van Ingen, Veerle Kremer, Laura Stanicek, Diewertje I. Bink, Anne Yaël Nossent
A large portion of the genome is transcribed into non-coding RNA, which does not encode protein. Many long non-coding RNAs (lncRNAs) have been shown to be involved in important regulatory processes such as genomic imprinting and chromatin modificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccb9c82bc8f411ed683a170d132aa434
https://doi.org/10.21203/rs.3.rs-800527/v1
https://doi.org/10.21203/rs.3.rs-800527/v1
Publikováno v:
Lozano-Vidal, N, Bink, D I & Boon, R A 2019, ' Long noncoding RNA in cardiac aging and disease ', Molecular and Cellular Biology, vol. 11, no. 10, pp. 860-867 . https://doi.org/10.1093/jmcb/mjz046
Journal of Molecular Cell Biology
Molecular and Cellular Biology, 11(10), 860-867
Journal of Molecular Cell Biology
Molecular and Cellular Biology, 11(10), 860-867
Cardiovascular diseases (CVDs) are the main cause of morbidity and mortality in Western society and present an important age-related risk. With the constant rise in life expectancy, prevalence of CVD in the population will likely increase further. Ne
Autor:
Marloes van den Berg, Stefan Conijn, Yeszamin Onderwater, Sylvia J. P. Bogaards, Zhong-Hua Shi, Pedro Espinosa, Marianna Bugiani, Martijn van de Locht, Hans van der Hoeven, Leo M. A. Heunks, Coen A.C. Ottenheijm, Diewertje I Bink, Reinier A Boon
Publikováno v:
BMJ open respiratory research, 8
BMJ open respiratory research, 8, 1
Shi, Z, Bogaards, S J P, Conijn, S, Onderwater, Y, Espinosa, P, Bink, D I, van den Berg, M, van de Locht, M, Bugiani, M, van der Hoeven, H, Boon, R A, Heunks, L & Ottenheijm, C A C 2021, ' COVID-19 is associated with distinct myopathic features in the diaphragm of critically ill patients ', BMJ Open Respiratory Research, vol. 8, no. 1, e001052 . https://doi.org/10.1136/bmjresp-2021-001052
BMJ Open Respiratory Research
BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
BMJ Open Respiratory Research, 8(1):e001052. BMJ Publishing Group
BMJ open respiratory research, 8, 1
Shi, Z, Bogaards, S J P, Conijn, S, Onderwater, Y, Espinosa, P, Bink, D I, van den Berg, M, van de Locht, M, Bugiani, M, van der Hoeven, H, Boon, R A, Heunks, L & Ottenheijm, C A C 2021, ' COVID-19 is associated with distinct myopathic features in the diaphragm of critically ill patients ', BMJ Open Respiratory Research, vol. 8, no. 1, e001052 . https://doi.org/10.1136/bmjresp-2021-001052
BMJ Open Respiratory Research
BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
BMJ Open Respiratory Research, 8(1):e001052. BMJ Publishing Group
IntroductionThe diaphragm is the main muscle of inspiration, and its dysfunction contributes to adverse clinical outcomes in critically ill patients. We recently reported the infiltration of SARS-CoV-2, and the development of fibrosis, in the diaphra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adeeb1936b7f67f9611f1e9c0d0c82e
http://hdl.handle.net/2066/238748
http://hdl.handle.net/2066/238748
Autor:
Boris Brill, Matthias S. Leisegang, Luisa Kirchhof, Tijna Alekseeva, Astrid Wietelmann, Kaja Yorgan, Stefanie Dimmeler, Jaya Krishnan, Stefan Engelhardt, Alexander M. Spring-Connell, Diewertje I. Bink, Marc N. Hirt, Corinne Bischof, Christopher N. Johnson, Anke van Bergen, Ralf P. Brandes, Janina Sommer, Riekelt H. Houtkooper, Thomas Eschenhagen, Ilka Wittig, Ariane Fischer, Chao-Chung Kuo, Nicolas Jaé, Manuel Kaulich, Patrick Hofmann, Stanislas Werfel, Ivan G. Costa, D. Julia Trembinski, Reinier A. Boon, Nazha Hamdani, Kosta Theodorou, Christoph Schürmann
Publikováno v:
Nature Communications, 11(1):2039. Nature Publishing Group UK
Nature Communications
Trembinski, D J, Bink, D I, Theodorou, K, Sommer, J, Fischer, A, van Bergen, A, Kuo, C C, Costa, I G, Schürmann, C, Leisegang, M S, Brandes, R P, Alekseeva, T, Brill, B, Wietelmann, A, Johnson, C N, Spring-Connell, A, Kaulich, M, Werfel, S, Engelhardt, S, Hirt, M N, Yorgan, K, Eschenhagen, T, Kirchhof, L, Hofmann, P, Jaé, N, Wittig, I, Hamdani, N, Bischof, C, Krishnan, J, Houtkooper, R H, Dimmeler, S & Boon, R A 2020, ' Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction ', Nature Communications, vol. 11, no. 1, 2039 . https://doi.org/10.1038/s41467-020-15995-2
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, 11(1):2039. Nature Publishing Group
Nature Communications
Trembinski, D J, Bink, D I, Theodorou, K, Sommer, J, Fischer, A, van Bergen, A, Kuo, C C, Costa, I G, Schürmann, C, Leisegang, M S, Brandes, R P, Alekseeva, T, Brill, B, Wietelmann, A, Johnson, C N, Spring-Connell, A, Kaulich, M, Werfel, S, Engelhardt, S, Hirt, M N, Yorgan, K, Eschenhagen, T, Kirchhof, L, Hofmann, P, Jaé, N, Wittig, I, Hamdani, N, Bischof, C, Krishnan, J, Houtkooper, R H, Dimmeler, S & Boon, R A 2020, ' Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction ', Nature Communications, vol. 11, no. 1, 2039 . https://doi.org/10.1038/s41467-020-15995-2
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, 11(1):2039. Nature Publishing Group
Long non-coding RNAs (lncRNAs) contribute to cardiac (patho)physiology. Aging is the major risk factor for cardiovascular disease with cardiomyocyte apoptosis as one underlying cause. Here, we report the identification of the aging-regulated lncRNA S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30d625577e97fb0a47fefa3a1339c0a
https://research.vumc.nl/en/publications/19dfbbe7-80a3-4a41-b4cb-98b9c8d2f34c
https://research.vumc.nl/en/publications/19dfbbe7-80a3-4a41-b4cb-98b9c8d2f34c