Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Dieudonnee Togbe"'
Autor:
Yasmine Messaoud-Nacer, Elodie Culerier, Stéphanie Rose, Isabelle Maillet, Nathalie Rouxel, Sylvain Briault, Bernhard Ryffel, Valerie F. J. Quesniaux, Dieudonnée Togbe
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-17 (2022)
Abstract Stimulator of interferon genes (STING) contributes to immune responses against tumors and may control viral infection including SARS-CoV-2 infection. However, activation of the STING pathway by airway silica or smoke exposure leads to cell d
Externí odkaz:
https://doaj.org/article/b029f36b907b43c58500531cbbc38f24
Autor:
Flora Reverchon, Vidian de Concini, Vanessa Larrigaldie, Sulayman Benmerzoug, Sylvain Briault, Dieudonnée Togbé, Bernhard Ryffel, Valérie F. J. Quesniaux, Arnaud Menuet
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background Interleukin (IL)-33 is expressed in a healthy brain and plays a pivotal role in several neuropathologies, as protective or contributing to the development of cerebral diseases associated with cognitive impairments. However, the ro
Externí odkaz:
https://doaj.org/article/5cf152ba8bdf45d28d68a94316b51d5e
Autor:
Céline Monnet, Emilie Jacque, Christophe de Romeuf, Alexandre Fontayne, Toufik Abache, Nathalie Fournier, Gilles Dupont, Delphine Derache, Anais Engrand, Aurélie Bauduin, Aurélie Terrier, Alexander Seifert, Cécile Beghin, Alain Longue, Nicholas Masiello, Laetitia Danino, Michel Nogre, Anais Raia, Frederic Dhainaut, Louis Fauconnier, Dieudonnée Togbe, Carmen Reitinger, Falk Nimmerjahn, Wil Stevens, Sami Chtourou, Philippe Mondon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Novel molecules that directly target the neonatal Fc receptor (FcRn) and/or Fc gamma receptors (FcγRs) are emerging as promising treatments for immunoglobulin G (IgG)-dependent autoimmune pathologies. Mutated Fc regions and monoclonal antibodies tha
Externí odkaz:
https://doaj.org/article/cb98171ccd1c4db4b09ceb279bdb5740
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/40ed7aeb9cf641bfb3a0d660a5247083
Autor:
Sulayman Benmerzoug, Stéphanie Rose, Badreddine Bounab, David Gosset, Laure Duneau, Pauline Chenuet, Lucile Mollet, Marc Le Bert, Christopher Lambers, Silvana Geleff, Michael Roth, Louis Fauconnier, Delphine Sedda, Clarisse Carvalho, Olivier Perche, David Laurenceau, Bernhard Ryffel, Lionel Apetoh, Ahmet Kiziltunc, Hakan Uslu, Fadime Sultan Albez, Metin Akgun, Dieudonnée Togbe, Valerie F. J. Quesniaux
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Silica particles induce intereukin-1 (IL-1) response to contribute to lung inflammation, but the underlying mechanism is unclear. Here the authors show that silica induces cell death and release of mitochondria and genomic DNA, which are sensed by ST
Externí odkaz:
https://doaj.org/article/9888d37e2d5a425d97df7c19aed7823f
Autor:
Zeinab Dalloul, Marie Best, Pauline Chenuet, Iman Dalloul, Sandrine Le Noir, Dieudonnée Togbé, Mylène Gador, Bernhard Ryffel, Valerie FJ Quesniaux, Yolla El Makhour, François Boyer, Jean‐Claude Aldigier, Jeanne Cook‐Moreau, Nicolas Fazilleau, Michel Cogné
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 6, Pp n/a-n/a (2021)
Abstract Objectives Inhibitors of bromodomain and extra terminal domain (BET) proteins are a new and growing class of anti‐cancer drugs, which decrease oncogene expression by targeting superenhancers. Antibody production is another physiological pr
Externí odkaz:
https://doaj.org/article/7f4552b0dd5f47e48599bdbc8b3cbc6d
Publikováno v:
Dose-Response, Vol 18 (2020)
In this study, we evaluated the efficacy of a micro-immunotherapy medicine (MIM), 2LALERG, in a preclinical model of allergic respiratory disease sensitized with birch pollen extract (BPE). BALB/c mice were immunized with BPE, or saline solution, and
Externí odkaz:
https://doaj.org/article/1fe77fc750f84065a3f572ae03926519
Autor:
Anna Gebhardt, Valter Bergant, Daniel Schnepf, Markus Moser, Arno Meiler, Dieudonnée Togbe, Claire Mackowiak, Line S Reinert, Søren R Paludan, Bernhard Ryffel, Alexey Stukalov, Peter Staeheli, Andreas Pichlmair
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008155 (2019)
Cellular response to environmental challenges requires immediate and precise regulation of transcriptional programs. During viral infections, this includes the expression of antiviral genes that are essential to combat the pathogen. Transcribed mRNAs
Externí odkaz:
https://doaj.org/article/2f2f0378c45148fa99debb5c174e921a
Autor:
Camille Jacques, Mathias Chatelais, Karim Fekir, Louis Fauconnier, Manon Mellier, Dieudonnée Togbe, Ilaria Floris
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 110 (2021)
This study aimed at evaluating the effects of the micro-immunotherapy medicine (MIM) 2LEID, both in vitro and in vivo, on several components of the innate and adaptive immune system. MIM increased the phagocytic activity of macrophages, and it augmen
Externí odkaz:
https://doaj.org/article/44421ab7c95f4fdb8ee663a87d168f19
Autor:
Milena Sokolowska, Valerie F. J. Quesniaux, Cezmi A. Akdis, Kian Fan Chung, Bernhard Ryffel, Dieudonnée Togbe
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Ozone exposure causes irritation, airway hyperreactivity (AHR), inflammation of the airways, and destruction of alveoli (emphysema), the gas exchange area of the lung in human and mice. This review focuses on the acute disruption of the respiratory e
Externí odkaz:
https://doaj.org/article/10a14524f2934f2cbb9c9bb3083afb2d