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Akademický článek

Short and Efficient Synthesis of the Antituberculosis Agent Pretomanid from ( R )-Glycidol.

Autor: Lucas T; Department of Chemistry, Johannes Gutenberg-University, Duesbergweg 10-14, 55128 Mainz, Germany., Dietz JP; Department of Chemistry, Johannes Gutenberg-University, Duesbergweg 10-14, 55128 Mainz, Germany., Cardoso FSP; Department of Chemical and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, United States., Snead DR; Department of Chemical and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, United States., Nelson RC; Department of Chemical and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, United States., Donsbach KO; Department of Chemical and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, United States., Gupton BF; Department of Chemical and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, United States., Opatz T; Department of Chemistry, Johannes Gutenberg-University, Duesbergweg 10-14, 55128 Mainz, Germany.

Publikováno v: Organic process research & development [Org Process Res Dev] 2023 Sep 05; Vol. 27 (9), pp. 1641-1651. Date of Electronic Publication: 2023 Sep 05 (Print Publication: 2023).

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Akademický článek

Diastereoselectivity is in the Details: Minor Changes Yield Major Improvements to the Synthesis of Bedaquiline.

Autor: Mear SJ; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Lucas T; Department of Chemistry, Johannes Gutenberg University, Duesbergweg 10-14, 55128, Mainz, Germany., Ahlqvist GP; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Robey JMS; Medicines for All Institute, Department of Chemistry and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia, 23284, USA., Dietz JP; Department of Chemistry, Johannes Gutenberg University, Duesbergweg 10-14, 55128, Mainz, Germany., Khairnar PV; Medicines for All Institute, Department of Chemistry and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia, 23284, USA., Maity S; Medicines for All Institute, Department of Chemistry and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia, 23284, USA., Williams CL; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Snead DR; Medicines for All Institute, Department of Chemistry and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia, 23284, USA., Nelson RC; Medicines for All Institute, Department of Chemistry and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia, 23284, USA., Opatz T; Department of Chemistry, Johannes Gutenberg University, Duesbergweg 10-14, 55128, Mainz, Germany., Jamison TF; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Aug 22; Vol. 28 (47), pp. e202201311. Date of Electronic Publication: 2022 Jul 07.

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Akademický článek

Di- tert -butyl Phosphonate Route to the Antiviral Drug Tenofovir.

Autor: Dietz JP; Department of Chemistry, Johannes Gutenberg-University, Duesbergweg 10-14, Mainz 55128, Germany., Ferenc D; Department of Chemistry, Johannes Gutenberg-University, Duesbergweg 10-14, Mainz 55128, Germany., Jamison TF; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge 02139, Massachusetts, United States., Gupton BF; Department of Chemical and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia 23284, United States., Opatz T; Department of Chemistry, Johannes Gutenberg-University, Duesbergweg 10-14, Mainz 55128, Germany.

Publikováno v: Organic process research & development [Org Process Res Dev] 2021 Feb 11; Vol. 25 (4), pp. 789-798. Date of Electronic Publication: 2021 Feb 11 (Print Publication: 2021).

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Akademický článek

A concise route to MK-4482 (EIDD-2801) from cytidine.

Autor: Vasudevan N; Medicines for All Institute, 737 N. 5th St., Box 980100, Richmond, VA 23298-0100, USA. drsnead@vcu.edu., Ahlqvist GP, McGeough CP, Paymode DJ, Cardoso FSP, Lucas T, Dietz JP, Opatz T, Jamison TF, Gupton FB, Snead DR

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Nov 11; Vol. 56 (87), pp. 13363-13364. Date of Electronic Publication: 2020 Oct 08.

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Akademický článek

Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt.

Autor: Lucas T; Institute of Organic Chemistry, Johannes Gutenberg-University, Duesbergweg 10-14, 55128 Mainz, Germany., Dietz JP; Institute of Organic Chemistry, Johannes Gutenberg-University, Duesbergweg 10-14, 55128 Mainz, Germany., Opatz T; Institute of Organic Chemistry, Johannes Gutenberg-University, Duesbergweg 10-14, 55128 Mainz, Germany.

Publikováno v: Beilstein journal of organic chemistry [Beilstein J Org Chem] 2020 Mar 20; Vol. 16, pp. 445-450. Date of Electronic Publication: 2020 Mar 20 (Print Publication: 2020).

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Akademický článek

Polyglycerol Surfmers and Surfactants for Direct and Inverse Miniemulsion.

Autor: Wald S; Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany., Simon J; Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany., Dietz JP; Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany., Wurm FR; Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany., Landfester K; Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.

Publikováno v: Macromolecular bioscience [Macromol Biosci] 2017 Oct; Vol. 17 (10). Date of Electronic Publication: 2017 Jun 29.

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Akademický článek

A Highly Active System for the Metal-Free Aerobic Photocyanation of Tertiary Amines with Visible Light: Application to the Synthesis of Tetraponerines and Crispine A.

Autor: Orejarena Pacheco JC; Institute of Organic Chemistry, University of Mainz, Duesbergweg 10-14, 55128, Mainz, Germany., Lipp A; Institute of Organic Chemistry, University of Mainz, Duesbergweg 10-14, 55128, Mainz, Germany., Nauth AM; Institute of Organic Chemistry, University of Mainz, Duesbergweg 10-14, 55128, Mainz, Germany., Acke F; Institute of Organic Chemistry, University of Mainz, Duesbergweg 10-14, 55128, Mainz, Germany., Dietz JP; Institute of Organic Chemistry, University of Mainz, Duesbergweg 10-14, 55128, Mainz, Germany., Opatz T; Institute of Organic Chemistry, University of Mainz, Duesbergweg 10-14, 55128, Mainz, Germany. opatz@uni-mainz.de.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2016 Apr 04; Vol. 22 (15), pp. 5409-15. Date of Electronic Publication: 2016 Mar 01.

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