Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dietrich Strub"'
Autor:
Klemens Kaupmann, Helmut Bittiger, Jakob Heid, Wolfgang Fröstl, Dietrich Strub, Bernhard Bettler, Stuart J. Mickel
Publikováno v:
Il Farmaco. 58:173-183
Outlined is the rationale behind the syntheses of radioligands [125I]CGP64213 and [125I]CGP71872, which led to the identification of cloned GABA(B) receptors 1a and 1b 17 years after the first pharmacological characterisation of native GABA(B) recept
Autor:
Stuart J. Mickel, Jakob Heid, Dietrich Strub, Klemens Kaupmann, Wolfgang Froestl, Bernhard Bettler, Helmut Bittiger
Publikováno v:
Neuropharmacology. 38:1641-1646
Since the discovery that the most abundant inhibitory neurotransmitter in the mammalian brain, GABA (gamma-aminobutyric acid), interacts not only with ionotropic GABA(A) receptors, but also with metabotropic GABA(B) receptors (Bowery et al., 1980) mu
Autor:
Stuart J. Mickel, Grety Rihs, Roger Graham Hall, P. C. Waldmeier, Conrad Gentsch, G. Von Sprecher, J. Jaekel, Helmut Bittiger, P. A. Baumann, Wolfgang Froestl, H. R. Olpe, Dietrich Strub, Felix Brugger, Annick Vassout
Publikováno v:
ChemInform. 26
Autor:
P. A. Baumann, Dietrich Strub, Stuart J. Mickel, Raymond Bernasconi, Wolfgang Froestl, Melillo, Roger Graham Hall, Ludwig Maier, P. J. Diel, von Sprecher G
Publikováno v:
Journal of medicinal chemistry. 38(17)
In 1987, 25 years after the synthesis of the potent and selective GABA B agonist baclofen (1), Kerr et al. 5 described the first GABA B antagonist phaclofen 2. However, phaclofen and structurally similar derivatives 3-5 did not cross the blood-brain
Autor:
Helmut Bittiger, Klemens Kaupmann, Jakob Heid, Dietrich Strub, Bernhard Bettler, Wolfgang Froestl, Stuart J. Mickel
Publikováno v:
Neuropharmacology. 38:1921
Erratum Erratum to ‘‘Ligands for the isolation of GABAB receptors’’ [Neuropharmacology 38 (1999), 1641–1646] Wolfgang Froestl *, Bernhard Bettler, Helmut Bittiger, Jakob Heid, Klemens Kaupmann, Stuart J. Mickel, Dietrich Strub No6artis Phar