Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Dietrich Scheglmann"'
Autor:
Ilya Yakavets, Henri-Pierre Lassalle, Dietrich Scheglmann, Arno Wiehe, Vladimir Zorin, Lina Bezdetnaya
Publikováno v:
Nanomaterials, Vol 8, Iss 10, p 847 (2018)
The main goal of this study was to use hybrid delivery system for effective transportation of temoporfin (meta-tetrakis(3-hydroxyphenyl)chlorin, mTHPC) to target tissue. We suggested to couple two independent delivery systems (liposomes and inclusion
Externí odkaz:
https://doaj.org/article/bf555d3539d44df39d68c23c8d279ae1
Autor:
Mukul Ashtikar, Annegret Preuß, Volker Albrecht, Harshvardhan Modh, Laura Jablonka, Beate Röder, Ge Fiona Gao, Jiong-Wei Wang, Matthias G. Wacker, Dietrich Scheglmann, Manuela Thurn
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 149:121-134
Over the years, the performance of the liposomal formulations of temoporfin, Foslip® and Fospeg®, was investigated in a broad array of cell-based assays and preclinical animal models. So far, little attention has been paid to the influence of drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cb7eeb094f4dcf84bcc7dad49e61ae
https://doi.org/10.1016/j.ejpb.2020.02.001
https://doi.org/10.1016/j.ejpb.2020.02.001
Autor:
Dietrich Scheglmann, Maria Mathieu-Gaedke, Hartwig R. A. Golf, Linda Elberskirch, Arno Wiehe, Hagen von Briesen, Sylvia Wagner, Ronan Le Harzic, Gerhard D. Wieland
The development of new tumor models for anticancer drug screening is a challenge for preclinical research. Conventional cell-based in vitro models such as 2D monolayer cell cultures or 3D spheroids allow an initial assessment of the efficacy of drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39187f91674a4bbd19f1f3ce56cb0e44
Autor:
Mukul Ashtikar, Ge Gao, Volker Albrecht, Laura Jablonka, Annegret Preuß, Fabian Jung, Matthias G. Wacker, Manuela Thurn, Beate Röder, Dietrich Scheglmann
Foscan®, a formulation comprising temoporfin dissolved in a mixture of ethanol and propylene glycol, has been approved in Europe for palliative photodynamic therapy of squamous cell carcinoma of the head and neck. During clinical and preclinical stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ded17ac4936a0ad29efa7b7c6c742b2
https://publica.fraunhofer.de/handle/publica/258767
https://publica.fraunhofer.de/handle/publica/258767
Autor:
Henri-Pierre Lassalle, Lina Bezdetnaya, Vladimir Zorin, Ilya Yakavets, Arno Wiehe, Dietrich Scheglmann
Publikováno v:
Nanomaterials
Volume 8
Issue 10
Nanomaterials, Vol 8, Iss 10, p 847 (2018)
Nanomaterials, MDPI, 2018, 8 (10), pp.847. ⟨10.3390/nano8100847⟩
Volume 8
Issue 10
Nanomaterials, Vol 8, Iss 10, p 847 (2018)
Nanomaterials, MDPI, 2018, 8 (10), pp.847. ⟨10.3390/nano8100847⟩
The main goal of this study was to use hybrid delivery system for effective transportation of temoporfin (meta-tetrakis(3-hydroxyphenyl)chlorin, mTHPC) to target tissue. We suggested to couple two independent delivery systems (liposomes and inclusion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b21807a7730b4844ebff528323a3a44
In cancer photodynamic therapy (PDT), an efficient and homogeneous intratumoral accumulation of the photosensitizer (PS) is required to induce cell damages in the entire tumor mass after light activation. Thus, in this study we investigated penetrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905c14410bf32bbd05b7af2c035b3607
http://hdl.handle.net/11577/3220427
http://hdl.handle.net/11577/3220427
Autor:
Josephine H. Woodhams, Francesca Moret, Alexander J. MacRobert, Wijnand Helfrich, Dietrich Scheglmann, Marco J. Verkaik, Elena Reddi, Lucia Celotti, Matija Rojnik, Petra Kocbek, Melissa J. Bovis, Emanuele Papini, Chiara Compagnin, Janko Kos
Publikováno v:
Nanomedicine, 7(5), 663-677
Nanomedicine; Vol 7
Nanomedicine; Vol 7
Aims: In this study we evaluated temoporfin-loaded polyethylene glycol (PEG) Poly-(D,L-lactide-co-glycolide) (PLGA) nanoparticles (NPs) as a new formulation for potential use in cancer treatment. Materials & methods: NPs were characterized for their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c37374cee60a5291f53836a0ffda16a
https://research.rug.nl/en/publications/756ad354-9068-47cd-a11f-54299e435322
https://research.rug.nl/en/publications/756ad354-9068-47cd-a11f-54299e435322
Autor:
Dennis Douroumis, Dietrich Scheglmann, Silvia Petersen, Alfred Fahr, Manfred Friedrich, Nina Dragicevic-Curic, Winfried Plass
Publikováno v:
International Journal of Pharmaceutics. 412:85-94
The aim of this study was to investigate the influence of membrane-softening components (terpenes/terpene mixtures, ethanol) on fluidity of phospholipid membranes in invasomes, which contain besides phosphatidylcholine and water, also ethanol and ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6eb1c1014e6f032f0d7c4e372cf6b2
https://doi.org/10.1016/j.ijpharm.2011.04.020
https://doi.org/10.1016/j.ijpharm.2011.04.020
Autor:
Mario Colucci, Emanuele Papini, Elena Reddi, Daniela Segat, Fabrizio Mancin, Selma Iratni, Dietrich Scheglmann, Janko Kos, Petra Kocbek, Regina Tavano, Francesco Selvestrel, Iria M. Rio Echevarria, Matija Rojnik
Publikováno v:
Nanomedicine
Nanomedicine; Vol 5
Nanomedicine; Vol 5
Aims: Undesired alterations of the blood clotting balance may follow the intravascular injection of nanotherapeutics/diagnostics. Here, we tested the procoagulant activity of synthetic amorphous silica (SAS) and organically modified silica (ORMOSIL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32aa011dea4ea3b0eab346ce5cbec9bb
https://doi.org/10.2217/nnm.10.65
https://doi.org/10.2217/nnm.10.65
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 74:114-122
The aim of this study was to develop ethanol-containing (3.3-20%, w/v) liposomes loaded with temoporfin (mTHPC), which presents a highly hydrophobic photosensitizer with low percutaneous penetration, and to investigate their skin penetration enhancin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90dc002c1a6680c603228efb77143546
https://doi.org/10.1016/j.colsurfb.2009.07.005
https://doi.org/10.1016/j.colsurfb.2009.07.005