Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Dietrich A, Stephan"'
Autor:
Robert M Friedlander, Valentina Di Caro, Diane L Carlisle, Noel R Monks, Dani M Stoltzfus, Natasha L Bennett, Yalikun Suofu, Jinho Kim, Fang Li, Xiaomin Wang, Stacy M Yeh, Oxana V Baranov, Sergei V Baranov, Barry A Badeau, Jeremy W Gleaton, Gabriel A Cintrón-Rosado, Ryan R Dyer, Dietrich A Stephan, William R Mann, Sandra E Rojas-Caro
Publikováno v:
I: Experimental therapeutics – preclinical.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfc23b4cea503d97ccdec42e9e3f4535
https://doi.org/10.1136/jnnp-2022-ehdn.232
https://doi.org/10.1136/jnnp-2022-ehdn.232
Autor:
Jason J. Corneveaux, Michael C. Kruer, Diane Hu-Lince, Keri E. Ramsey, Victoria L. Zismann, Dietrich A. Stephan, David W. Craig, Matthew J. Huentelman
Publikováno v:
BioTechniques, Vol 42, Iss 1, Pp 77-83 (2007)
Whole genome amplification by multiple displacement amplification (MDA) offers investigators using precious genomic DNA samples a high fidelity method for amplifying nanogram quantities of DNA several thousandfold. This becomes especially important f
Externí odkaz:
https://doaj.org/article/35e79f8cc9664fe69e93818bd8d8ff97
Autor:
Dietrich A. Stephan
Publikováno v:
Journal of Commercial Biotechnology. 26
NeuBase is accelerating the genetic revolution by developing a new class of precision genetic medicines which can be designed to increase, decrease, or change gene function, as appropriate, to resolve genetic defects that drive disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d45961dfd16a896961ab7571af3d3011
https://doi.org/10.5912/jcb995
https://doi.org/10.5912/jcb995
Autor:
Mark D Alter, Rutwik Kharkar, Keri E Ramsey, David W Craig, Raun D Melmed, Theresa A Grebe, R Curtis Bay, Sharman Ober-Reynolds, Janet Kirwan, Josh J Jones, J Blake Turner, Rene Hen, Dietrich A Stephan
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16715 (2011)
A causal role of mutations in multiple general transcription factors in neurodevelopmental disorders including autism suggested that alterations in global levels of gene expression regulation might also relate to disease risk in sporadic cases of aut
Externí odkaz:
https://doaj.org/article/100cf6822b1f40fa9b99804d6a46dd8c
Autor:
Badri Padhukasahasram, Eran Halperin, Jennifer Wessel, Daryl J Thomas, Elana Silver, Heather Trumbower, Michele Cargill, Dietrich A Stephan
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14338 (2010)
The prevalence of common chronic non-communicable diseases (CNCDs) far overshadows the prevalence of both monogenic and infectious diseases combined. All CNCDs, also called complex genetic diseases, have a heritable genetic component that can be used
Externí odkaz:
https://doaj.org/article/a3469e949b314daaa83d3436ef23cf0a
Autor:
Mark D Alter, Daniel B Rubin, Keri Ramsey, Rebecca Halpern, Dietrich A Stephan, L F Abbott, Rene Hen
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3344 (2008)
Despite sharing the same genes, identical twins demonstrate substantial variability in behavioral traits and in their risk for disease. Epigenetic factors-DNA and chromatin modifications that affect levels of gene expression without affecting the DNA
Externí odkaz:
https://doaj.org/article/6310475dcffc489db429a4342cd66cc4
Autor:
Nils Homer, Szabolcs Szelinger, Margot Redman, David Duggan, Waibhav Tembe, Jill Muehling, John V Pearson, Dietrich A Stephan, Stanley F Nelson, David W Craig
Publikováno v:
PLoS Genetics, Vol 4, Iss 8, p e1000167 (2008)
We use high-density single nucleotide polymorphism (SNP) genotyping microarrays to demonstrate the ability to accurately and robustly determine whether individuals are in a complex genomic DNA mixture. We first develop a theoretical framework for det
Externí odkaz:
https://doaj.org/article/c9895e435c9a4521b761c40ee612f8a4
Autor:
Dietrich A Stephan, Anoop Grewal
Publikováno v:
Personalized medicine. 10(8)
The era of personalized medicine is upon us and it is being fueled by large available data sets of many types that are setting the foundation for the development of more precise diagnostic tools and targeted therapies, which are improving patient out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf5e1d68310bd2cfea6f8c1b4315929
https://pubmed.ncbi.nlm.nih.gov/29776283
https://pubmed.ncbi.nlm.nih.gov/29776283
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 1, Pp 1312-1335 (2015)
International Journal of Molecular Sciences
Volume 16
Issue 1
Pages 1312-1335
International Journal of Molecular Sciences
Volume 16
Issue 1
Pages 1312-1335
Classical autism or autistic disorder belongs to a group of genetically heterogeneous conditions known as Autism Spectrum Disorders (ASD). Heritability is estimated as high as 90% for ASD with a recently reported compilation of 629 clinically relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e81214f30a8e6391362adde2ed403a
https://doi.org/10.3390/ijms16011312
https://doi.org/10.3390/ijms16011312
Autor:
Dietrich A. Stephan
Publikováno v:
Recent Patents on DNA & Gene Sequences. 6:175-179
An extraordinary revolution in medical research has taken place over the past decade, enabled by the completion of the first human genome sequence in 2001. The Human Genome Project (HGP) has resulted in the 6 billion letter reference human genome seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c39f5738496d08aa187d8b0f489f279
https://doi.org/10.2174/187221512802717376
https://doi.org/10.2174/187221512802717376