Zobrazeno 1 - 10
of 605
pro vyhledávání: '"Dietmar W Hutmacher"'
Autor:
Michael Wagels, Thomas Lloyd, Nicola Ward, Marjoree Sehu, David S Sparks, Jay Wiper, Marie-Luise Wille, Flavia M Savi, Dietmar W Hutmacher
Publikováno v:
BMJ Open, Vol 13, Iss 5 (2023)
Introduction Reconstruction of critical bone defects is challenging. In a substantial subgroup of patients, conventional reconstructive techniques are insufficient. Biodegradable scaffolds have emerged as a novel tissue engineering strategy for criti
Externí odkaz:
https://doaj.org/article/1a01a246a7e548a5ab4a0aecd23c4f11
Autor:
Isabel Gonzalez Matheus, Dietmar W Hutmacher, Sarah Olson, Michael Redmond, Allison Sutherland, Michael Wagels
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 10, p e36111 (2022)
BackgroundLarge skull defects present a reconstructive challenge. Conventional cranioplasty options include autologous bone grafts, vascularized bone, metals, synthetic ceramics, and polymers. Autologous options are affected by resorption and residua
Externí odkaz:
https://doaj.org/article/74015e0ee9ca4e0e9076b2af29078c73
Publikováno v:
HardwareX, Vol 8, Iss , Pp e00152- (2020)
Automation liberates scientific staff from repetitive tasks, decreases the probability of human error and consequently enhances the reproducibility of lab experiments. However, the use of laboratory automation in academic laboratories is limited due
Externí odkaz:
https://doaj.org/article/24d165098a034316bdeb3acffea1fd43
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Advancements in cell therapy have the potential to improve healthcare accessibility for eligible patients. However, there are still challenges in scaling production and reducing costs. These challenges involve various stakeholders such as the manufac
Externí odkaz:
https://doaj.org/article/f4a48e117330461d91409fe9a023c2f6
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113216 (2014)
There is a need for materials that are well suited for cartilage tissue engineering. Hydrogels have emerged as promising biomaterials for cartilage repair, since, like cartilage, they have high water content, and they allow cells to be encapsulated w
Externí odkaz:
https://doaj.org/article/54392f7378a44d2498dde74baf74dc17
Autor:
Shirly Sieh, Anna V Taubenberger, Simone C Rizzi, Martin Sadowski, Melanie L Lehman, Anja Rockstroh, Jiyuan An, Judith A Clements, Colleen C Nelson, Dietmar W Hutmacher
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e40217 (2012)
Biophysical and biochemical properties of the microenvironment regulate cellular responses such as growth, differentiation, morphogenesis and migration in normal and cancer cells. Since two-dimensional (2D) cultures lack the essential characteristics
Externí odkaz:
https://doaj.org/article/3ae1c03cc7664588b81ef6f282d896d5
Autor:
Matthew Cheng, Jan Janzekovic, Ronja Finze, Mina Mohseni, Siamak Saifzadeh, Flavia M. Savi, Owen Ung, Michael Wagels, Dietmar W. Hutmacher
Publikováno v:
Bioengineering, Vol 11, Iss 6, p 593 (2024)
Scaffold-guided breast tissue regeneration (SGBTR) can transform both reconstructive and cosmetic breast surgery. Implant-based surgery is the most common method. However, there are inherent limitations, as it involves replacement of tissue rather th
Externí odkaz:
https://doaj.org/article/097efac4614544db9839858128816b44
Autor:
Jacqui A. McGovern, Nathalie Bock, Abbas Shafiee, Laure C. Martine, Ferdinand Wagner, Jeremy G. Baldwin, Marietta Landgraf, Christoph A. Lahr, Christoph Meinert, Elizabeth D. Williams, Pamela M. Pollock, Jim Denham, Pamela J. Russell, Gail P. Risbridger, Judith A. Clements, Daniela Loessner, Boris M. Holzapfel, Dietmar W. Hutmacher
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
McGovern et al. establish an orthotopic, humanized prostate cancer model to study bone metastasis. The authors demonstrate that a humanized tumor microenvironment (TME) influences the metastatic spread of cancer cells to tissue-engineered bone, highl
Externí odkaz:
https://doaj.org/article/faf5250036f045d891a483661ad13556
Autor:
Stephen Whyte, PhD, Laura Bray, PhD, Ho Fai Chan, PhD, Raymond J. Chan, PhD, Jeremy Hunt, MBBS, FRACS, Tim S. Peltz, PhD, MBBS, Uwe Dulleck, PhD, Dietmar W. Hutmacher, PhD
Publikováno v:
Annals of Surgery Open, Vol 3, Iss 2, p e176 (2022)
Objectives:. To explore information seeking behavior on medical innovations. Background:. While autologous and alloplastic options for breast reconstruction are well established, it is the advent of the combination of 3D printing technology and the b
Externí odkaz:
https://doaj.org/article/1774478d5d5344a891aea1d19c8bd7b9
Autor:
Buddhi Herath, Sinduja Suresh, David Downing, Silvia Cometta, Rance Tino, Nathan J. Castro, Martin Leary, Beat Schmutz, Marie-Luise Wille, Dietmar W. Hutmacher
Publikováno v:
Materials & Design, Vol 212, Iss , Pp 110224- (2021)
The Voronoi design was utilized for a biodegradable patient-specific bone scaffold with macro pores (>4 mm) for the surgical treatment of a critical-sized bone defect. We have focused on the relationship between scaffold design and mechanical propert
Externí odkaz:
https://doaj.org/article/93db452a25c64b8e909e3bbcc6a23baa