Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Dietmar Utesch"'
Publikováno v:
Mutation Research/Reviews in Mutation Research. 771:85-98
The present review describes available evidence about the fate of micronuclei and micronucleated cells. Micronuclei are small, extranuclear chromatin bodies surrounded by a nuclear envelope. The mechanisms underlying the formation of micronuclei are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb7e424d58724b5efcb0dc780fbbf4d
https://doi.org/10.1016/j.mrrev.2017.02.002
https://doi.org/10.1016/j.mrrev.2017.02.002
Autor:
B. Danielewska-Nikiel, T.H. Broschard, J. Dasenbrock, Dietmar Utesch, K. Feige, T.C. Lines, M. Harwood
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 654:38-44
Quercetin, a naturally occurring flavonol commonly detected in apples, cranberries, blueberries, and onions, has been reported to possess antioxidant, anti-carcinogenic, anti-inflammatory, and cardioprotective properties. While positive results have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0323bfa7facabff1cd76acabdf6ebb61
https://doi.org/10.1016/j.mrgentox.2008.04.008
https://doi.org/10.1016/j.mrgentox.2008.04.008
Autor:
Nicola J. Hewitt, Franz Oesch, Jan G. Hengstler, Beate Reder-Hilz, M. Ringel, M. Ullrich, Dietmar Utesch
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 369:408-417
In the present study we examined the metabolism of [(14)C]propafenone (P) and [(14)C]verapamil (V) using cryopreserved human, dog (Beagle), rat (Sprague-Dawley) and mouse (NMRI) hepatocytes. The percentage ratios of the metabolites were identified af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9bdeb3245e7bf1f31f3664f0a080ccc
https://doi.org/10.1007/s00210-004-0875-z
https://doi.org/10.1007/s00210-004-0875-z
Autor:
Bernd Epe, Dietmar Utesch, Lutz Müller, Bernd Kaina, Susanne Brendler-Schwaab, Elmar Gocke, Andreas Czich, Dieter Pollet
Publikováno v:
Mutation Research/Reviews in Mutation Research. 566:65-91
In recent years, assessing the photogenotoxic potential of a compound became an issue for certain drugs and cosmetical products. Therefore, existing methods performed according to international guidelines (e.g. OECD guidelines) were adapted to the us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d73dd28b8e9a7affb8584e0d91dafe4
https://doi.org/10.1016/s1383-5742(03)00052-8
https://doi.org/10.1016/s1383-5742(03)00052-8
Autor:
Dietmar Utesch, Naveed Honarvar, Renate Slacik-Erben, Rudolf Fahrig, Silvio Albertini, Günter Engelhardt, Bernd Görlitz, Franziska Pötter-Locher, Sinead McKiernan, Wilhelm von der Hude, Helga Stopper, Peter Kasper, Herbert G. Miltenburger, Stephan Madle, Sabine Kalweit, Stephan Kirchner
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 468:137-163
A collaborative study with 10 participating laboratories was conducted to evaluate a test protocol for the performance of the in vitro micronucleus (MN) test using the V79 cell line with one treatment and one sampling time only. A total of 26 coded s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38397f2e6b64b88b2ea4e03d7157124f
https://doi.org/10.1016/s1383-5718(00)00045-0
https://doi.org/10.1016/s1383-5718(00)00045-0
Autor:
Angelika Seelbach, Franziska Pötter-Locher, Beate Miller, Helga Stopper, Stephan Madle, Dietmar Utesch
Publikováno v:
Mutation Research/Reviews in Mutation Research. 410:81-116
In order to license a pharmaceutical or chemical, a compound has to be tested for several genotoxicity endpoints, including the induction of chromosomal aberrations in vitro. A working group within the GUM has evaluated published data on the in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d5e218927ba4b5839c239662955c415
https://doi.org/10.1016/s1383-5742(97)00030-6
https://doi.org/10.1016/s1383-5742(97)00030-6
Autor:
Nicola J. Swales, Dietmar Utesch
Publikováno v:
Xenobiotica. 28:937-948
1. Dog hepatocytes were cryopreserved at 6 x 10(6) viable cells/ml in a suspension buffer containing 10% DMSO and were stored in liquid nitrogen. 2. The exclusion of trypan blue dye was 96 +/- 2 and 85 +/- 9% in fresh and cryopreserved (CP) hepatocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0e5e640413134b92d9913831900290
https://doi.org/10.1080/004982598239001
https://doi.org/10.1080/004982598239001
Publikováno v:
Polycyclic Aromatic Compounds. 10:117-121
The cytotoxicity of various PAH was determined in V79 Chinese hamster fibroblasts in the absence and presence of a solar simulator, i.e. a light source emitting visible light, including UV-A and UV-B components. The range of cytotoxic concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24377120a6ea9d05ffb63945adc2cf0b
https://doi.org/10.1080/10406639608034687
https://doi.org/10.1080/10406639608034687
Publikováno v:
Cryobiology. 30:116-127
An optimized computer-controlled freezing protocol for the cryopreservation of rat liver parenchymal cells was developed. The best survival rates were obtained when a slow cooling rate was used and when the supercooling was interrupted with a shock c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda95c8cc40c5884f06178791634e57a
https://doi.org/10.1006/cryo.1993.1011
https://doi.org/10.1006/cryo.1993.1011
Autor:
Ingolf Gath, Peter Maier, Dietmar Utesch, Margarete Traiser, Franz Oesch, Adriaan W.C. Dorresteijn
Publikováno v:
Carcinogenesis. 14:457-462
The effects of sodium butyrate, which has been shown to act as a differentiation promoting agent in several different tumor cell lines, were studied in a rat liver nonparenchymal epithelial cell line. Exposure of these cells to 3.75 mM butyrate resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da0a263d7e0845332da5906978b0da2
https://doi.org/10.1093/carcin/14.3.457
https://doi.org/10.1093/carcin/14.3.457