Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Dietmar R, Thal"'
Autor:
Araks Martirosyan, Rizwan Ansari, Francisco Pestana, Katja Hebestreit, Hayk Gasparyan, Razmik Aleksanyan, Silvia Hnatova, Suresh Poovathingal, Catherine Marneffe, Dietmar R. Thal, Andrew Kottick, Victor J. Hanson-Smith, Sebastian Guelfi, William Plumbly, T. Grant Belgard, Emmanouil Metzakopian, Matthew G. Holt
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-24 (2024)
Abstract Parkinson’s Disease (PD) is the second most common neurodegenerative disorder. The pathological hallmark of PD is loss of dopaminergic neurons and the presence of aggregated α-synuclein, primarily in the substantia nigra pars compacta (SN
Externí odkaz:
https://doaj.org/article/ac5a812e7fc64915b2e68e33cecdd4a4
Autor:
Bram De Wel, Lotte Huysmans, Christophe E. Depuydt, Veerle Goosens, Ronald Peeters, Filipa P. Santos, Dietmar R. Thal, Patrick Dupont, Frederik Maes, Kristl G. Claeys
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 3, Pp 1468-1481 (2023)
Abstract Background Despite the widespread use of proton density fat fraction (PDFF) measurements with magnetic resonance imaging (MRI) to track disease progression in muscle disorders, it is still unclear how these findings relate to histopathologic
Externí odkaz:
https://doaj.org/article/f286867d6bd14e3eb8e4d4ab26587d3a
Autor:
Araks Martirosyan, Rizwan Ansari, Francisco Pestana, Katja Hebestreit, Hayk Gasparyan, Razmik Aleksanyan, Silvia Hnatova, Suresh Poovathingal, Catherine Marneffe, Dietmar R. Thal, Andrew Kottick, Victor J. Hanson-Smith, Sebastian Guelfi, William Plumbly, T. Grant Belgard, Emmanouil Metzakopian, Matthew G. Holt
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5bf4088beae54ac38e53d043a1ffdfc6
Autor:
Lize Vanaken, F.J. Sherida H. Woei-A-Jin, Rita Van Ginderdeuren, Christophe M. Deroose, Annouschka Laenen, Guy Missotten, Dietmar R. Thal, Oliver Bechter, Patrick Schöffski, Paul Clement
Publikováno v:
Acta Oncologica. :1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ab60f574d4625eccf3b2522f70069b7
https://doi.org/10.1080/0284186x.2023.2211206
https://doi.org/10.1080/0284186x.2023.2211206
Autor:
Christophe E. Depuydt, Veerle Goosens, Rekin’s Janky, Ann D’Hondt, Jan L. De Bleecker, Nathalie Noppe, Stefaan Derveaux, Dietmar R. Thal, Kristl G. Claeys
Publikováno v:
Cells, Vol 11, Iss 9, p 1508 (2022)
Limb-girdle muscular dystrophy R12 (LGMD-R12) is caused by two mutations in anoctamin-5 (ANO5). Our aim was to identify genes and pathways that underlie LGMD-R12 and explain differences in the molecular predisposition and susceptibility between three
Externí odkaz:
https://doaj.org/article/0e52b24be709489a9f5d4a0e9a80e5b2
Autor:
Annelies Nonneman, Nathan Criem, Sebastian A. Lewandowski, Rik Nuyts, Dietmar R. Thal, Frank W. Pfrieger, John Ravits, Philip Van Damme, An Zwijsen, Ludo Van Den Bosch, Wim Robberecht
Publikováno v:
Neurobiology of Disease, Vol 119, Iss , Pp 26-40 (2018)
Amyotrophic lateral sclerosis (ALS) is a late-onset devastating degenerative disease mainly affecting motor neurons. Motor neuron degeneration is accompanied and aggravated by oligodendroglial pathology and the presence of reactive astrocytes and mic
Externí odkaz:
https://doaj.org/article/540696d1c29544e4af2c75d91b8a269f
Autor:
Matei Bolborea, Pauline Vercruysse, Tselmen Daria, Johanna C. Reiners, Najwa Ouali Alami, Simon J. Guillot, Stéphane Dieterlé, Jérôme Sinniger, Jelena Scekic-Zahirovic, Amela Londo, Hippolyte Arcay, Marc-Antoine Goy, Claudia Nelson de Tapia, Dietmar R. Thal, Kazumoto Shibuya, Ryo Otani, Kimihito Arai, Satoshi Kuwabara, Albert C. Ludolph, Francesco Roselli, Deniz Yilmazer-Hanke, Luc Dupuis
Publikováno v:
Acta neuropathologica 145(6), 773-791 (2023). doi:10.1007/s00401-023-02569-x
Amyotrophic lateral sclerosis (ALS) is associated with impaired energy metabolism, including weight loss and decreased appetite which are negatively correlated with survival. Neural mechanisms underlying metabolic impairment in ALS remain unknown. AL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f18d3d203fa3b8454fd5faf2f5793b7
https://lirias.kuleuven.be/handle/20.500.12942/719930
https://lirias.kuleuven.be/handle/20.500.12942/719930
Autor:
Lukas J. Schnitzler, Tobias Schreckenbach, Aleksandra Nadaj-Pakleza, Werner Stenzel, Elisabeth J. Rushing, Philip Van Damme, Andreas Ferbert, Susanne Petri, Christian Hartmann, Antje Bornemann, Andreas Meisel, Jens A. Petersen, Thomas Tousseyn, Dietmar R. Thal, Jens Reimann, Peter De Jonghe, Jean-Jacques Martin, Peter Y. Van den Bergh, Jörg B. Schulz, Joachim Weis, Kristl G. Claeys
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-12 (2017)
Abstract Background Sporadic late-onset nemaline myopathy (SLONM) is a rare, late-onset muscle disorder, characterized by the presence of nemaline rods in muscle fibers. Phenotypic characterization in a large cohort and a comprehensive overview of SL
Externí odkaz:
https://doaj.org/article/d683de3e2eeb4e0290c805d869e0301b
Autor:
Matteo Riva, Roxanne Wouters, Akila Weerasekera, Sarah Belderbos, David Nittner, Dietmar R. Thal, Thaïs Baert, Roberto Giovannoni, Willy Gsell, Uwe Himmelreich, Marc Van Ranst, An Coosemans
Publikováno v:
Biology Open, Vol 8, Iss 9 (2019)
Recently, several promising treatments for high-grade gliomas (HGGs) failed to provide significant benefit when translated from the preclinical setting to patients. Improving the animal models is fundamental to overcoming this translational gap. To a
Externí odkaz:
https://doaj.org/article/389ce9713eb24efbb4a1fad3618bc73e
Autor:
Araks Martirosyan, Francisco Pestana, Katja Hebestreit, Hayk Gasparyan, Razmik Aleksanyan, Suresh Poovathingal, Catherine Marneffe, Dietmar R. Thal, Andrew Kottick, Victor Hanson-Smith, Sebastian Guelfi, Emmanouil Metzakopian, T. Grant Belgard
Parkinson’s Disease (PD) is the second most common neurodegenerative disorder and is generally characterized by impaired motor functions. It currently affects 6.3 million people aged 60 years and more, worldwide. The pathological hallmarks of PD ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4bfedce228d2dbb5d7bb0c8f112ae5e
https://doi.org/10.1101/2023.01.04.522691
https://doi.org/10.1101/2023.01.04.522691