Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Dietmar M. W. Zaiss"'
Autor:
Serena P. H. Mao, Minji Park, Ramon M. Cabrera, John R. Christin, George S. Karagiannis, Maja H. Oktay, Dietmar M. W. Zaiss, Scott I. Abrams, Wenjun Guo, John S. Condeelis, Paraic A. Kenny, Jeffrey E. Segall
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-14 (2018)
Abstract Background Amphiregulin (AREG), a ligand of the epidermal growth factor receptor, is not only essential for proper mammary ductal development, but also associated with breast cancer proliferation and growth. In the absence of AREG, mammary d
Externí odkaz:
https://doaj.org/article/55ca17d6078546279abba37a1a8209dc
Autor:
Simran S. Kapoor, Dietmar M. W. Zaiss
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 52 (2021)
Several types of tumours overexpress the Epidermal Growth Factor Receptor (EGFR) in either wild type or mutated form. These tumours are often highly aggressive and difficult to treat. The underlying mechanisms for this phenomenon have remained largel
Externí odkaz:
https://doaj.org/article/0514e4f3905e4dd9bda68a7568133f06
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Epidermal Growth Factor Receptor (EGFR) antagonists were one of the first anti-cancer treatments developed targeting a Receptor Tyrosine Kinase. However, the underlying mode of action of how EGFR antagonist application can explain its clinical effica
Externí odkaz:
https://doaj.org/article/ade01866466e45738058af58afe00a29
Autor:
Chantal Meulenbroeks, Jaco J van der Lugt, Nathalie M A van der Meide, Ton Willemse, Victor P M G Rutten, Dietmar M W Zaiss
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122090 (2015)
The immunological mechanisms explaining development of an allergy in some individuals and not in others remain incompletely understood. Insect bite hypersensitivity (IBH) is a common, seasonal, IgE-mediated, pruritic skin disorder that affects consid
Externí odkaz:
https://doaj.org/article/41a886b608e6422bbf5dbd01c7b17044
Autor:
Suyasha Roy, Zaigham Abbas Rizvi, Anna Kathrina Simon, Amit Awasthi, Alexander J. Clarke, Dietmar M. W. Zaiss, Felicity Macdonald, Abhaydeep Pandey
Publikováno v:
Roy, S, Abbas Rizvi, Z, Clarke, A J, Macdonald, F, Pandey, A, Zaiss, D M W, Simon, A K & Awasthi, A 2021, ' EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells ', Nature Communications . https://doi.org/10.1038/s41467-021-23042-x
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Interleukin 9 (IL-9)-producing helper T (Th9) cells are essential for inducing anti-tumor immunity and inflammation in allergic and autoimmune diseases. Although transcription factors that are essential for Th9 cell differentiation have been identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b5c5abaecbef6d685c21241938da41
https://hdl.handle.net/20.500.11820/7a7a75bf-68e9-4324-aae6-61359ea490ac
https://hdl.handle.net/20.500.11820/7a7a75bf-68e9-4324-aae6-61359ea490ac
Publikováno v:
Jenkins, S J, Knipper, J A & Zaiss, D M W 2020, ' Local proliferation of monocytes ', Journal of Leukocyte Biology . https://doi.org/10.1002/JLB.1CE0220-534RR
Discussion on how monocytes may contribute to the expansion of Mϕ populations at the site of inflammation.
Publikováno v:
Clin Exp Immunol
Vukovic, N, van Elsas, A, Verbeek, J S & Zaiss, D M W 2020, ' Isotype selection for antibody-based cancer therapy ', Clinical & Experimental Immunology, pp. 1-15 . https://doi.org/10.1111/cei.13545
Clinical & Experimental Immunology
Vukovic, N, van Elsas, A, Verbeek, J S & Zaiss, D M W 2020, ' Isotype selection for antibody-based cancer therapy ', Clinical & Experimental Immunology, pp. 1-15 . https://doi.org/10.1111/cei.13545
Clinical & Experimental Immunology
SummaryThe clinical application of monoclonal antibodies (mAbs) has revolutionized the field of cancer therapy, as it has enabled the successful treatment of previously untreatable types of cancer. Different mechanisms play a role in the anti-tumour
Autor:
Dietmar M. W. Zaiss, Salim Harraou, Andrea van Elsas, Natasa Vukovic, Sander M.J. van Duijnhoven
Publikováno v:
Vukovic, N, Harraou, S, Van Duijnhoven, S M J, Zaiss, D M & Van Elsas, A 2020, ' Purification of murine immunoglobulin E (IgE) by thiophilic interaction chromatography (TIC) ', Journal of Immunological Methods . https://doi.org/10.1016/j.jim.2020.112914
Journal of Immunological Methods
Journal of Immunological Methods
In addition to their known implication in allergy studies, IgE antibodies are becoming an increasingly interesting antibody class in cancer research. However, large-scale purification of IgE antibodies still poses substantial challenges, as they cann
Autor:
Dietmar M. W. Zaiss
Publikováno v:
Am J Transplant
Zaiss, D 2019, ' Amphiregulin as a driver of tissue fibrosis ', American Journal of Transplantation . https://doi.org/10.1111/ajt.15743
Zaiss, D 2019, ' Amphiregulin as a driver of tissue fibrosis ', American Journal of Transplantation . https://doi.org/10.1111/ajt.15743
Chronic lung allograft dysfunction (CLAD), a condition of excess matrix deposition and airways fibrosis, limits survival after lung transplantation. Amphiregulin (Areg) is an epidermal growth factor receptor (EGFR) ligand suggested to regulate airway
Publikováno v:
Immunology
Zaiss, D, Munoz Minutti, C & Knipper, J 2019, ' Immune and non-immune mediated roles of regulatory T-cells during wound healing ', Immunology . https://doi.org/10.1111/imm.13057
Zaiss, D, Munoz Minutti, C & Knipper, J 2019, ' Immune and non-immune mediated roles of regulatory T-cells during wound healing ', Immunology . https://doi.org/10.1111/imm.13057
The immune system has a well-established contribution to tissue homeostasis and wound healing. However, in many cases immune responses themselves can cause severe tissue damage. Thus, the question arose to which extent cells of the immune system dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ce1d96ecd5b48ed57f0008302ffa19
https://europepmc.org/articles/PMC6600083/
https://europepmc.org/articles/PMC6600083/