Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Dietmar Fischer"'
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 12, Pp 2557-2558 (2024)
Externí odkaz:
https://doaj.org/article/9e0824d09066423fbbe687c87137fda2
Autor:
Marco Leibinger, Charlotte Zeitler, Miriam Paulat, Philipp Gobrecht, Alexander Hilla, Anastasia Andreadaki, Rainer Guthoff, Dietmar Fischer
Publikováno v:
eLife, Vol 12 (2023)
Injured axons in the central nervous system (CNS) usually fail to regenerate, causing permanent disabilities. However, the knockdown of Pten knockout or treatment of neurons with hyper-IL-6 (hIL-6) transforms neurons into a regenerative state, allowi
Externí odkaz:
https://doaj.org/article/ba03f88517c04c51a9fe454aa6c3094c
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 2, Pp 338-340 (2022)
Externí odkaz:
https://doaj.org/article/0589b06fa13843d9a833e0402c3dee2d
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 7, Pp 1481-1483 (2022)
Externí odkaz:
https://doaj.org/article/13919321721847749c27adaf53fffcd9
Autor:
Marco Leibinger, Charlotte Zeitler, Philipp Gobrecht, Anastasia Andreadaki, Günter Gisselmann, Dietmar Fischer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The CNS has limited ability to regenerate following injury, Here, the authors show that a single injection of AAV-hyper-interleukin-6 in the sensory motor cortex results in corticospinal and raphe spinal tracts regeneration in the injured spinal cord
Externí odkaz:
https://doaj.org/article/d04a0d94e0664f95b2ee84617b7516de
Autor:
Andrés Cruz-Herranz, Michael Dietrich, Alexander M. Hilla, Hao H. Yiu, Marc H. Levin, Christina Hecker, Andrea Issberner, Angelika Hallenberger, Christian Cordano, Klaus Lehmann-Horn, Lisanne J. Balk, Orhan Aktas, Jens Ingwersen, Charlotte von Gall, Hans-Peter Hartung, Scott S. Zamvil, Dietmar Fischer, Philipp Albrecht, Ari J. Green
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-17 (2019)
Abstract Background Retinal optical coherence tomography (OCT) is a clinical and research tool in multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and ganglion cell (RGC) layer thinning, while postmortem studies have repo
Externí odkaz:
https://doaj.org/article/6292cc19ece1420483d1add71284f30e
Autor:
Michael Dietrich, Niklas Helling, Alexander Hilla, Annemarie Heskamp, Andrea Issberner, Thomas Hildebrandt, Zippora Kohne, Patrick Küry, Carsten Berndt, Orhan Aktas, Dietmar Fischer, Hans-Peter Hartung, Philipp Albrecht
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-13 (2018)
Abstract Background In multiple sclerosis (MS), neurodegeneration is the main reason for chronic disability. Alpha-lipoic acid (LA) is a naturally occurring antioxidant which has recently been demonstrated to reduce the rate of brain atrophy in progr
Externí odkaz:
https://doaj.org/article/917bb5029cf84d02a108d41eae546601
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Muscle lim protein (MLP) has long been regarded as a cytosolic and nuclear muscular protein. Here, we show that MLP is also expressed in a subpopulation of adult rat dorsal root ganglia (DRG) neurons in response to axonal injury, while the p
Externí odkaz:
https://doaj.org/article/ecc4ac228ffb400ab40fff9b4b8d38f9
Autor:
Alexander Hilla, Dietmar Fischer
Publikováno v:
Bio-Protocol, Vol 8, Iss 16 (2018)
Microglia reside in the central nervous system (CNS) and are involved in the maintenance of the physiologic state. They constantly survey their environment for pathologic alterations associated with injury or diseases. For decades, researchers have i
Externí odkaz:
https://doaj.org/article/d23da55b50194b82868110dc18b02aab
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 11, Pp 1907-1908 (2019)
Externí odkaz:
https://doaj.org/article/e581192ef26f427cb0630fb852448cbe