Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Dietmar E. Martin"'
Autor:
Laura V Glaser, Simone Rieger, Sybille Thumann, Sophie Beer, Cornelia Kuklik-Roos, Dietmar E Martin, Kerstin C Maier, Marie L Harth-Hertle, Björn Grüning, Rolf Backofen, Stefan Krebs, Helmut Blum, Ralf Zimmer, Florian Erhard, Bettina Kempkes
Publikováno v:
PLoS Pathogens, Vol 13, Iss 10, p e1006664 (2017)
Epstein-Barr virus (EBV) infection converts resting human B cells into permanently proliferating lymphoblastoid cell lines (LCLs). The Epstein-Barr virus nuclear antigen 2 (EBNA2) plays a key role in this process. It preferentially binds to B cell en
Externí odkaz:
https://doaj.org/article/9ead8bedc269442990447aa13ffbca21
Autor:
Pauline Wales, Christian E Schuberth, Roland Aufschnaiter, Johannes Fels, Ireth García-Aguilar, Annette Janning, Christopher P Dlugos, Marco Schäfer-Herte, Christoph Klingner, Mike Wälte, Julian Kuhlmann, Ekaterina Menis, Laura Hockaday Kang, Kerstin C Maier, Wenya Hou, Antonella Russo, Henry N Higgs, Hermann Pavenstädt, Thomas Vogl, Johannes Roth, Britta Qualmann, Michael M Kessels, Dietmar E Martin, Bela Mulder, Roland Wedlich-Söldner
Publikováno v:
eLife, Vol 5 (2016)
Actin has well established functions in cellular morphogenesis. However, it is not well understood how the various actin assemblies in a cell are kept in a dynamic equilibrium, in particular when cells have to respond to acute signals. Here, we chara
Externí odkaz:
https://doaj.org/article/1c44cc24da5646788f05eaf82ed3042d
Autor:
Dietmar E. Martin, Bernhard Liebl, Susanne Muehlich, Kerstin C. Maier, Miriam J. Franz, Regine Schneider-Stock, Dagmar Fischer, Constanze Mittermeier, Laura Schreyer, Melanie A. Meier, Kerstin Huebner, Stephan Singer, Silvia Ribback, Thomas Gudermann, Kerstin Holzer, Achim Aigner
Publikováno v:
Cancers, Vol 13, Iss 5373, p 5373 (2021)
Cancers
Volume 13
Issue 21
Cancers
Volume 13
Issue 21
Simple Summary Hepatocellular carcinoma (HCC) ranks second among the leading causes of cancer-related death. Since current therapeutic options are very limited, a deeper understanding of the molecular mechanisms underlying the tumor onset and progres
Autor:
Theresa Niederberger, Stefanie Etzold, Michael Lidschreiber, Kerstin C Maier, Dietmar E Martin, Holger Fröhlich, Patrick Cramer, Achim Tresch
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 6, p e1002568 (2012)
The Mediator is a highly conserved, large multiprotein complex that is involved essentially in the regulation of eukaryotic mRNA transcription. It acts as a general transcription factor by integrating regulatory signals from gene-specific activators
Externí odkaz:
https://doaj.org/article/dd20bb50e6d840f99cb48e1863c7201b
Autor:
Christine S Schmidt, Sebastian Bultmann, Daniela Meilinger, Benedikt Zacher, Achim Tresch, Kerstin C Maier, Christian Peter, Dietmar E Martin, Heinrich Leonhardt, Fabio Spada
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52629 (2012)
DNA methylation patterns change dynamically during mammalian development and lineage specification, yet scarce information is available about how DNA methylation affects gene expression profiles upon differentiation. Here we determine genome-wide tra
Externí odkaz:
https://doaj.org/article/e6e1f0bff7034c81a856144ed05a2fad
Autor:
Martin Seizl, Holger Hartmann, Friederike Hoeg, Fabian Kurth, Dietmar E Martin, Johannes Söding, Patrick Cramer
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27595 (2011)
Initiation of RNA polymerase (Pol) II transcription requires assembly of the pre-initiation complex (PIC) at the promoter. In the classical view, PIC assembly starts with binding of the TATA box-binding protein (TBP) to the TATA box. However, a TATA
Externí odkaz:
https://doaj.org/article/9add49ee4c654a1499cd970ef3210061
Autor:
Margarete Goppelt-Struebe, Kerstin Holzer, Alfred Nordheim, Nina Waldburger, Constanze Hermanns, Stephanie Roessler, Susanne Muehlich, J Penkava, Thomas Gudermann, Abhishek Thavamani, Kerstin C. Maier, Natasha Y. Frank, Dietmar E. Martin, Achim Aigner, Stephan Singer, Ivana Akrap, V Hampl
Publikováno v:
Oncogene. 36:3464-3476
Megakaryoblastic Leukemia 1 and 2 (MKL1/2) are transcriptional coactivators of Serum Response Factor (SRF) with an essential role for hepatocellular carcinoma (HCC) growth and oncogene-induced senescence. In this report, we identified myoferlin as a
Autor:
Dietmar E. Martin, Sybille Thumann, Cornelia Kuklik-Roos, Laura V. Glaser, Sophie Beer, Ralf Zimmer, Bettina Kempkes, Stefan Krebs, Helmut Blum, Kerstin C. Maier, Marie L. Harth-Hertle, Florian Erhard, Björn Grüning, Simone Rieger, Rolf Backofen
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 10, p e1006664 (2017)
PLoS Pathog. 13, e1006664:e1006664 (2017)
PLoS Pathogens, Vol 13, Iss 10, p e1006664 (2017)
PLoS Pathog. 13, e1006664:e1006664 (2017)
Epstein-Barr virus (EBV) infection converts resting human B cells into permanently proliferating lymphoblastoid cell lines (LCLs). The Epstein-Barr virus nuclear antigen 2 (EBNA2) plays a key role in this process. It preferentially binds to B cell en
Autor:
Bela M. Mulder, Roland Aufschnaiter, Antonella Russo, Roland Wedlich-Söldner, Johannes Fels, Thomas Vogl, Dietmar E. Martin, Laura Hockaday Kang, Ekaterina Menis, Wenya Hou, Julian Kuhlmann, Christopher P Dlugos, Michael M. Kessels, Mike Wälte, Kerstin C. Maier, Pauline Wales, Christian Schuberth, C. Klingner, Ireth García-Aguilar, Marco Schäfer-Herte, Johannes Roth, Hermann Pavenstädt, Britta Qualmann, Henry N. Higgs, Annette Janning
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife
Actin has well established functions in cellular morphogenesis. However, it is not well understood how the various actin assemblies in a cell are kept in a dynamic equilibrium, in particular when cells have to respond to acute signals. Here, we chara
Autor:
Kristin Leike, Andreas Mayer, Patrick Cramer, Amelie Schreieck, Michael Lidschreiber, Dietmar E. Martin
Publikováno v:
Molecular and Cellular Biology
During transcription elongation, RNA polymerase II (Pol II) binds the general elongation factor Spt5. Spt5 contains a repetitive C-terminal region (CTR) that is required for cotranscriptional recruitment of the Paf1 complex (D. L. Lindstrom et al., M