Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Dietmar Rabussay"'
Autor:
Diane Hebblewaite, Peter Silvera, Jan zur Megede, Dawn Golightly, John J. Donnelly, Brigitte E Sanders-Beer, Jeffrey B. Ulmer, Ranjana Srivastava, Susan W. Barnett, Abigail Bowlsbey, Dietmar Rabussay, Gillis R. Otten, Lei Zhang, Lourdes Nieves-Duran, Deborah Sites
Publikováno v:
AIDS Research and Human Retroviruses. 24:1103-1116
The immunologic and virologic outcome of therapeutic DNA-vaccines administered during antiretroviral therapy (ART) using electroporation with or without (interleukin) IL-2 treatment was evaluated in the SIV-mac239/macaque model. Rhesus macaques inocu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab915dede18c729bc880af9ca2dc1343
https://doi.org/10.1089/aid.2008.0055
https://doi.org/10.1089/aid.2008.0055
Publikováno v:
Vaccine. 25:6635-6645
We evaluated the effectiveness of in vivo electroporation (EP) for the enhancement of immune responses induced by DNA plasmids encoding the pre-erythrocytic Plasmodium yoelii antigens PyCSP and PyHEP17 administered intramuscularly and intradermally t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870af25c940d40a5519cfdc0a996f935
https://doi.org/10.1016/j.vaccine.2007.06.036
https://doi.org/10.1016/j.vaccine.2007.06.036
Autor:
Randolph Seidler, Henri Doods, Susanne Ailinger, Dietmar Rabussay, Andreas Sterner, Martin Lenter, Susanne Allgäuer, Nagendu B. Dev
Publikováno v:
Pharmaceutical Research. 22:1685-1691
The purpose of this study was to develop a nonviral gene transfer method for therapeutic delivery of the human monocyte chemoattractant protein-1 (MCP-1) in patients with peripheral artery disease, using local catheter-mediated electrotransfer of nak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcc2cf128104cd7fdf38213d5a63fef
https://doi.org/10.1007/s11095-005-6334-9
https://doi.org/10.1007/s11095-005-6334-9
Autor:
Georg Widera, Marianna Foldvari, Lawrence Baizer, Maria E. Baca-Estrada, Michael Storms, Dietmar Rabussay, Richard Stout, Shawn Babiuk, Lorne A. Babiuk
Publikováno v:
Molecular Therapy. 8:992-998
Electroporation has been shown to increase the potency of DNA vaccines that have demonstrated significant potential in mice. However, there is a need to develop noninvasive or minimally invasive vaccination methods. In pigs, in vivo gene expression w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29277ed054f23217bcfc7ce6347d5365
https://doi.org/10.1016/j.ymthe.2003.09.008
https://doi.org/10.1016/j.ymthe.2003.09.008
Publikováno v:
Annals of Biomedical Engineering. 31:80-90
The goal of this study was to collect a comprehensive set of data that related lethal effects of electric fields to the duration of the pulse. Electric pulses of different strengths and durations were applied to a suspension of HEp-2 cells (epidermoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c139fd46516f6fbf2b4b397f7dba4fe
https://doi.org/10.1114/1.1531634
https://doi.org/10.1114/1.1531634
Publikováno v:
Journal of Interventional Cardiology. 13:331-338
The present study examined the use of electroporation (pulsed electric field application) to temporarily permeabilize vascular cell membranes and thereby deliver drugs directly into cells of the vessel wall to treat focal cardiovascular diseases (e.g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bdf08ff68939ff867e051b0544cadd4
https://doi.org/10.1111/j.1540-8183.2000.tb00311.x
https://doi.org/10.1111/j.1540-8183.2000.tb00311.x
Publikováno v:
Clinical Aspects of Electroporation ISBN: 9781441983626
There are many positive attributes to DNA vaccination that make it a conceptually desirable platform. In clinical studies, however, standard DNA injection alone generally induces low levels of transgene-specific immunity when compared to other vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8182bb9b202b6b2efd12b20a78e1b542
https://doi.org/10.1007/978-1-4419-8363-3_18
https://doi.org/10.1007/978-1-4419-8363-3_18
Autor:
Dietmar, Rabussay
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 423
As in vivo electroporation advances from the preclinical phase to clinical studies and eventually to routine medical practice, the design of electroporation devices becomes increasingly important. Achieving safety and efficacy levels that meet regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8499cc2e98a5eb6d859d495bdbfef40
https://pubmed.ncbi.nlm.nih.gov/18370189
https://pubmed.ncbi.nlm.nih.gov/18370189
Autor:
Torunn Elisabeth, Tjelle, Dietmar, Rabussay, Christian, Ottensmeier, Iacob, Mathiesen, Rune, Kjeken
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 423
We are presently aware of two early-phase DNA vaccine clinical trials in humans using electroporation-enhanced vaccine delivery. Moreover, two phase I immunogenetherapy studies are in progress and several tolerability studies have been performed on h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1b29a74f5752fc51bedc29f297e764d
https://pubmed.ncbi.nlm.nih.gov/18370225
https://pubmed.ncbi.nlm.nih.gov/18370225
Autor:
Iacob Mathiesen, Christian H. Ottensmeier, Torunn Elisabeth Tjelle, Dietmar Rabussay, Rune Kjeken
Publikováno v:
Methods in Molecular Biology ISBN: 9781588298775
We are presently aware of two early-phase DNA vaccine clinical trials in humans using electroporation-enhanced vaccine delivery. Moreover, two phase I immunogenetherapy studies are in progress and several tolerability studies have been performed on h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4290871cf22e21e9dcfa93858c95268
https://doi.org/10.1007/978-1-59745-194-9_39
https://doi.org/10.1007/978-1-59745-194-9_39