Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Dietmar, Schmucker"'
Autor:
Manuela D. Mitsogiannis, Anna Pancho, Tania Aerts, Sonja M. Sachse, Ria Vanlaer, Lut Noterdaeme, Dietmar Schmucker, Eve Seuntjens
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Down Syndrome (DS) Cell Adhesion Molecules (DSCAMs) are transmembrane proteins of the immunoglobulin superfamily. Human DSCAM is located within the DS critical region of chromosome 21 (duplicated in Down Syndrome patients), and mutations or copy-numb
Externí odkaz:
https://doaj.org/article/67af4e66c58f49a0a43d969dafb639ac
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 8, Pp 2309-2318 (2016)
Clustered protocadherins (cPcdhs) constitute the largest subgroup of the cadherin superfamily, and in mammals are grouped into clusters of α-, β-, and γ-types. Tens of tandemly arranged paralogous Pcdh genes of the Pcdh clusters generate a substan
Externí odkaz:
https://doaj.org/article/e8bd4536ff8d4fe7899c42292d11a9fb
Autor:
Marta Koch, Maya Nicolas, Marlen Zschaetzsch, Natalie de Geest, Annelies Claeys, Jiekun Yan, Matthew J. Morgan, Maria-Luise Erfurth, Matthew Holt, Dietmar Schmucker, Bassem A. Hassan
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2018)
Injury to the adult central nervous systems (CNS) can result in severe long-term disability because damaged CNS connections fail to regenerate after trauma. Identification of regulators that enhance the intrinsic growth capacity of severed axons is a
Externí odkaz:
https://doaj.org/article/8cf8885497d447a4a2c78e569f59525b
Publikováno v:
Current Opinion in Neurobiology. 66:158-165
Recent progress in human genetics and single cell sequencing rapidly expands the list of molecular factors that offer important new contributions to our understanding of brain wiring. Yet many new molecular factors are being discovered that have neve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b089fc5fd2fb3e04534224657f39edc
https://doi.org/10.1016/j.conb.2020.10.019
https://doi.org/10.1016/j.conb.2020.10.019
Autor:
Gabriela Edwards-Faret, Filip de Vin, Michal Slezak, Lennart Gollenbeck, Ruçhan Karaman, Yohei Shinmyo, Mykhailo Y. Batiuk, Carmen Menacho Pando, Johann Urschitz, Melvin Y. Rincon, Stefan Moisyadi, Frank Schnütgen, Hiroshi Kawasaki, Dietmar Schmucker, Matthew G. Holt
Publikováno v:
Neuroscience.
Advances in single cell sequencing have enabled the identification of a large number of genes, expressed in many different cell types, and across a variety of model organisms. In particular, the nervous system harbors an immense number of interacting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f879821ad1808dd6c5a27d4bda1b65
https://pubmed.ncbi.nlm.nih.gov/36464177
https://pubmed.ncbi.nlm.nih.gov/36464177
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108660 (2014)
The hypervariable Dscam1 (Down syndrome cell adhesion molecule 1) gene can produce thousands of different ectodomain isoforms via mutually exclusive alternative splicing. Dscam1 appears to be involved in the immune response of some insects and crusta
Externí odkaz:
https://doaj.org/article/676e3403b28548f2ba46b1f7b5735bfb
Autor:
Marion Langen, Marta Koch, Jiekun Yan, Natalie De Geest, Maria-Luise Erfurth, Barret D Pfeiffer, Dietmar Schmucker, Yves Moreau, Bassem A Hassan
Publikováno v:
eLife, Vol 2 (2013)
Brain connectivity maps display a delicate balance between individual variation and stereotypy, suggesting the existence of dedicated mechanisms that simultaneously permit and limit individual variation. We show that during the development of the Dro
Externí odkaz:
https://doaj.org/article/258d5181d118405eb0d694e1b6c5a305
Publikováno v:
Current opinion in neurobiology. 66
Recent progress in human genetics and single cell sequencing rapidly expands the list of molecular factors that offer important new contributions to our understanding of brain wiring. Yet many new molecular factors are being discovered that have neve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::618af4ad60520820b2b09131dce4d481
https://pubmed.ncbi.nlm.nih.gov/33232861
https://pubmed.ncbi.nlm.nih.gov/33232861
Autor:
Sonja Sachse, Olivier Urwyler, Sofie Vandenbogaerde, Anke Misbaer, Dietmar Schmucker, Azadeh Izadifar
Publikováno v:
Science. 364
Compartmentalization of axons Neurons can spread branches far and wide across the central nervous system. One neuron can simultaneously contact several other neurons, amplifying network complexity. Studying the Drosophila brain, Urwyler et al. found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a9006e1915981e1b4f170999f6ef16f
https://doi.org/10.1126/science.aau9952
https://doi.org/10.1126/science.aau9952
Autor:
Anke Misbaer, Delphine Masschaele, Wouter Van Delm, Katrien Horré, Maria-Luise Erfurth, Sonja Sachse, Joris de Wit, Sam Lievens, Yoshiaki Kise, Bart De Strooper, Stéphane Plaisance, Dietmar Schmucker, Evgenia Salta, Nele Vanderroost, Dan Dascenco, Siegfried Nebel, Anne Sophie de Smet, Luís Ribeiro, Jan Tavernier
Publikováno v:
The EMBO journal
DSCAM and DSCAML1 are immunoglobulin and cell adhesion-type receptors serving important neurodevelopmental functions including control of axon growth, branching, neurite self-avoidance, and neuronal cell death. The signal transduction mechanisms or e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2bb638a832643dbeeea7cf723c8efa
https://doi.org/10.15252/embj.201899669
https://doi.org/10.15252/embj.201899669