Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Dietlind L Gerloff"'
Enzyme-assisted high throughput sequencing of an expanded genetic alphabet at single base resolution
Autor:
Bang Wang, Kevin M. Bradley, Myong-Jung Kim, Roberto Laos, Cen Chen, Dietlind L. Gerloff, Luran Manfio, Zunyi Yang, Steven A. Benner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract With just four building blocks, low sequence information density, few functional groups, poor control over folding, and difficulties in forming compact folds, natural DNA and RNA have been disappointing platforms from which to evolve recepto
Externí odkaz:
https://doaj.org/article/025d698ec3364749b2c91f336ff28175
Autor:
Darshankumar T Pathak, Xueming Wei, Alex Bucuvalas, Daniel H Haft, Dietlind L Gerloff, Daniel Wall
Publikováno v:
PLoS Genetics, Vol 8, Iss 4, p e1002626 (2012)
Biofilms are dense microbial communities. Although widely distributed and medically important, how biofilm cells interact with one another is poorly understood. Recently, we described a novel process whereby myxobacterial biofilm cells exchange their
Externí odkaz:
https://doaj.org/article/89baf91714174c0a81ab1c45d5d3112e
Autor:
Fred Kippert, Dietlind L Gerloff
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7148 (2009)
BACKGROUND:HEAT and ARM repeats occur in a large number of eukaryotic proteins. As these repeats are often highly diverged, the prediction of HEAT or ARM domains can be challenging. Except for the most clear-cut cases, identification at the individua
Externí odkaz:
https://doaj.org/article/7b9f5cf497944336b1b0901bf054e6ba
Autor:
Dietlind L. Gerloff, Elena I. Ilina, Camille Cialini, Uxue Mata Salcedo, Michel Mittelbronn, Tanja Müller
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101905- (2023)
Summary: A significant number of proteins are annotated as functionally uncharacterized proteins. Within this protocol, we describe how to use protein family multiple sequence alignments and structural bioinformatics resources to design loss-of-funct
Externí odkaz:
https://doaj.org/article/97f3ec72c1fa4615ab273b26a6270375
Autor:
Elena I. Ilina, Camille Cialini, Dietlind L. Gerloff, Maitane Duarte Garcia-Escudero, Céline Jeanty, Marie-Laëtitia Thézénas, Antoine Lesur, Vincent Puard, François Bernardin, Alina Moter, Anne Schuster, Monika Dieterle, Anna Golebiewska, Jean-Jacques Gérardy, Gunnar Dittmar, Simone P. Niclou, Tanja Müller, Michel Mittelbronn
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103842- (2022)
Summary: Glioblastoma (GBM) is the most aggressive primary brain tumor characterized by infiltrative growth of malignant glioma cells into the surrounding brain parenchyma. In this study, our analysis of GBM patient cohorts revealed a significantly h
Externí odkaz:
https://doaj.org/article/9391a4f387d04c32af06e8d9af82961b
Autor:
Dietlind L. Gerloff, Elena I. Ilina, Camille Cialini, Uxue Mata Salcedo, Michel Mittelbronn, Tanja Müller
Publikováno v:
STAR protocols. 4(1)
A significant number of proteins are annotated as functionally uncharacterized proteins. Within this protocol, we describe how to use protein family multiple sequence alignments and structural bioinformatics resources to design loss-of-function mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179edcb1c4175da8cd7da22899a3d86f
https://pubmed.ncbi.nlm.nih.gov/36528856
https://pubmed.ncbi.nlm.nih.gov/36528856
Publikováno v:
mBio, Vol 5, Iss 1 (2014)
ABSTRACT More than 20% of all protein domains are currently annotated as “domains of unknown function” (DUFs). About 2,700 DUFs are found in bacteria compared with just over 1,500 in eukaryotes. Over 800 DUFs are shared between bacteria and eukar
Externí odkaz:
https://doaj.org/article/16274d4b4b704f6fa2be7de04534a22c
Autor:
Tanja R. Müller, Monika Dieterle, Jean-Jacques Gérardy, Anne Schuster, Michel Mittelbronn, Elena I. Ilina, Céline Jeanty, Maitane Duarte Garcia-Escudero, Camille Cialini, Simone P. Niclou, Alina Moter, Gunnar Dittmar, Dietlind L. Gerloff, Vincent Puard, Anna Golebiewska
Publikováno v:
SSRN Electronic Journal.
Glioblastoma (GBM) is the most aggressive primary brain tumor characterized by infiltrative migration of malignant glioma cells into the surrounding brain parenchyma. In this study, our analysis of GBM patient cohorts displayed significant higher exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0f381ad6f136b076d3cf948b7332e5f
https://doi.org/10.2139/ssrn.3862019
https://doi.org/10.2139/ssrn.3862019
Autor:
Christian B. Winiger, Mariko F. Matsuura, Myong-Jung Kim, Steven A. Benner, Jennifer D. Moses, Shuichi Hoshika, Dietlind L. Gerloff, Ryan W. Shaw
Publikováno v:
Biochemistry
In addition to completing the Watson-Crick nucleobase matching "concept" (big pairs with small, hydrogen bond donors pair with hydrogen bond acceptors), artificially expanded genetic information systems (AEGIS) also challenge DNA polymerases with a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44e474647ba3da046907a4e606b4ff1
https://doi.org/10.1021/acs.biochem.6b00533
https://doi.org/10.1021/acs.biochem.6b00533
Autor:
Dale S. Martin, Dietlind L. Gerloff, Geetha P. Bansal, Dibyadyuti Datta, Nirbhay Kumar, Mario T. Philipp, Brooke Grasperge, Drew Hannaman, Barry Ellefsen
Publikováno v:
Vaccine. 35(50)
Antibodies recognizing conformational epitopes in Pfs48/45, an antigen expressed on the surface of Plasmodium falciparum gametes and zygotes, have firmly established Pfs48/45 as a promising transmission blocking vaccine (TBV) candidate. However, it h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0a23805efb44f40db5660a0191f39d
https://pubmed.ncbi.nlm.nih.gov/29132995
https://pubmed.ncbi.nlm.nih.gov/29132995