Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Dieter-Henrik Heiland"'
Autor:
Dominik Koessinger, Amir El Rahal, Pierre Scheffler, Jakob Straehle, NIcolas Neidert, Dieter-Henrik Heiland, Christian Fung, Juergen Beck, Oliver Schnell
Publikováno v:
Brain and Spine, Vol 3, Iss , Pp 102124- (2023)
Externí odkaz:
https://doaj.org/article/2ceadd72a7984cd5bc189946ed433ab6
Autor:
Joris Guyon, Ignacio Fernandez‐Moncada, Claire M Larrieu, Cyrielle L Bouchez, Antonio C Pagano Zottola, Johanna Galvis, Tiffanie Chouleur, Audrey Burban, Kevin Joseph, Vidhya M Ravi, Heidi Espedal, Gro Vatne Røsland, Boutaina Daher, Aurélien Barre, Benjamin Dartigues, Slim Karkar, Justine Rudewicz, Irati Romero‐Garmendia, Barbara Klink, Konrad Grützmann, Marie‐Alix Derieppe, Thibaut Molinié, Nina Obad, Céline Léon, Giorgio Seano, Hrvoje Miletic, Dieter Henrik Heiland, Giovanni Marsicano, Macha Nikolski, Rolf Bjerkvig, Andreas Bikfalvi, Thomas Daubon
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp 1-20 (2022)
Abstract Lactate is a central metabolite in brain physiology but also contributes to tumor development. Glioblastoma (GB) is the most common and malignant primary brain tumor in adults, recognized by angiogenic and invasive growth, in addition to its
Externí odkaz:
https://doaj.org/article/ba568585186d48d99efb5ec52859e399
Autor:
Vidhya M. Ravi, Nicolas Neidert, Paulina Will, Kevin Joseph, Julian P. Maier, Jan Kückelhaus, Lea Vollmer, Jonathan M. Goeldner, Simon P. Behringer, Florian Scherer, Melanie Boerries, Marie Follo, Tobias Weiss, Daniel Delev, Julius Kernbach, Pamela Franco, Nils Schallner, Christine Dierks, Maria Stella Carro, Ulrich G. Hofmann, Christian Fung, Roman Sankowski, Marco Prinz, Jürgen Beck, Henrike Salié, Bertram Bengsch, Oliver Schnell, Dieter Henrik Heiland
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The tumour microenvironment counteracts immune therapy in Glioblastomas. Authors show here, using spatially resolved and single cell transcriptomics, that dysfunctional T cells are induced by a myeloid cell subset via Interleukin-10 signalling, and i
Externí odkaz:
https://doaj.org/article/c8ede93aa6744a97b9b18e93349c871a
Autor:
Julian P. Maier, Vidhya M. Ravi, Jan Kueckelhaus, Simon P. Behringer, Niklas Garrelfs, Paulina Will, Na Sun, Jasmin von Ehr, Jonathan M. Goeldner, Dietmar Pfeifer, Marie Follo, Luciana Hannibal, Axel Karl Walch, Ulrich G. Hofmann, Jürgen Beck, Dieter Henrik Heiland, Oliver Schnell, Kevin Joseph
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Abstract Glioblastoma (GBM), the most malignant tumor of the central nervous system, is marked by its dynamic response to microenvironmental niches. In particular, this cellular plasticity contributes to the development of an immediate resistance dur
Externí odkaz:
https://doaj.org/article/b89ed836d7234b6e8298f323cfead154
Autor:
Waseem Masalha, Karam Daka, Jakob Woerner, Nils Pompe, Stefan Weber, Daniel Delev, Marie T. Krüger, Oliver Schnell, Jürgen Beck, Dieter Henrik Heiland, Juergen Grauvogel
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Meningiomas are common brain tumours that are usually defined by benign clinical course. However, some meningiomas undergo a malignant transformation and recur within a short time period regardless of their World Health Organizati
Externí odkaz:
https://doaj.org/article/a3e0a86df9f54702bfdc85b9982ad874
Autor:
Waseem Masalha, Dieter Henrik Heiland, Christine Steiert, Marie T. Krueger, Daniel Schnell, Christian Scheiwe, Anca-L. Grosu, Oliver Schnell, Juergen Beck, Juergen Grauvogel
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionPetroclival meningioma (PCM) remains a major neurosurgical challenge. There are still controversial strategic treatment concepts about surgical approach, the extent of resection, and postoperative radiotherapy. We aimed to evaluate progno
Externí odkaz:
https://doaj.org/article/8ace183813ff4a1bb29316c73d6b2bf3
Autor:
Waseem Masalha, Dieter Henrik Heiland, Christine Steiert, Marie T. Krüger, Daniel Schnell, Christian Scheiwe, Oliver Schnell, Anca-L. Grosu, Jürgen Beck, Jürgen Grauvogel
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectiveSpheno-orbital meningiomas (SOM) are rare intracranial tumors that arise at the sphenoid wing. These tumors can invade important neurovascular structures making radical resection difficult, while residual tumors often lead to recurrence. The
Externí odkaz:
https://doaj.org/article/a1ba069efc734b56a74fdbdc1c9a7412
Autor:
Dieter Henrik Heiland, Vidhya M. Ravi, Simon P. Behringer, Jan Hendrik Frenking, Julian Wurm, Kevin Joseph, Nicklas W. C. Garrelfs, Jakob Strähle, Sabrina Heynckes, Jürgen Grauvogel, Pamela Franco, Irina Mader, Matthias Schneider, Anna-Laura Potthoff, Daniel Delev, Ulrich G. Hofmann, Christian Fung, Jürgen Beck, Roman Sankowski, Marco Prinz, Oliver Schnell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Astrocytes play important roles in neuroinflammatory diseases. Here the authors characterize human glioblastoma-associated astrocytes by gene expression and demonstrate their immunosuppressive role promoted by interactions with tumor and microglia ce
Externí odkaz:
https://doaj.org/article/bda58627bc774fe381635dc078c37616
Autor:
Sabrina Heynckes, Karam Daka, Pamela Franco, Annette Gaebelein, Jan Hendrik Frenking, Roberto Doria-Medina, Irina Mader, Daniel Delev, Oliver Schnell, Dieter Henrik Heiland
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background In recent years, PD-1/PD-L1 immune checkpoint inhibitors have improved cancer therapy in many tumor types, but no benefit of immune checkpoint therapy has been found in glioblastoma multiforme (GBM). Based on the results of our ea
Externí odkaz:
https://doaj.org/article/eb8b96f01e0c4d828266b0d73c52ad85
Autor:
Franz L. Ricklefs, Cecile L. Maire, Rudolph Reimer, Lasse Dührsen, Katharina Kolbe, Mareike Holz, Enja Schneider, Anne Rissiek, Anna Babayan, Claudia Hille, Klaus Pantel, Susanne Krasemann, Markus Glatzel, Dieter Henrik Heiland, Jörg Flitsch, Tobias Martens, Nils Ole Schmidt, Sven Peine, Xandra O. Breakefield, Sean Lawler, E. Antonio. Chiocca, Boris Fehse, Bernd Giebel, André Görgens, Manfred Westphal, Katrin Lamszus
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Cells release heterogeneous nano-sized vesicles either as exosomes, being derived from endosomal compartments, or through budding from the plasma membrane as so-called microvesicles, commonly referred to as extracellular vesicles (EVs). EVs are known
Externí odkaz:
https://doaj.org/article/078f5e4797aa4830bc23165fa77949da