Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Dieter W, Heermann"'
Autor:
Fatema-Zahra M. Rashid, Frédéric G. E. Crémazy, Andreas Hofmann, David Forrest, David C. Grainger, Dieter W. Heermann, Remus T. Dame
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Nucleoid associated proteins (NAPs) maintain the architecture of bacterial chromosomes and regulate gene expression. Thus, their role as transcription factors may involve three-dimensional chromosome re-organisation. While this model is supp
Externí odkaz:
https://doaj.org/article/e5591af993724439831c95bd12cafc31
Autor:
Satyaprakash Pandey, Mona Hajikazemi, Theresa Zacheja, Stephanie Schalbetter, Jonathan Baxter, Victor Guryev, Andreas Hofmann, Dieter W. Heermann, Stefan A. Juranek, Katrin Paeschke
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background The main function of telomerase is at the telomeres but under adverse conditions telomerase can bind to internal regions causing deleterious effects as observed in cancer cells. Results By mapping the global occupancy of the catal
Externí odkaz:
https://doaj.org/article/49015b42ea7c44bda95a827b3a9a2668
Autor:
Sujeet Kumar Mishra, Kunhe Li, Simon Brauburger, Arnab Bhattacherjee, Nestor Norio Oiwa, Dieter W. Heermann
Publikováno v:
Life, Vol 12, Iss 4, p 541 (2022)
Nucleosome positioning plays an important role in crucial biological processes such as replication, transcription, and gene regulation. It has been widely used to predict the genome’s function and chromatin organisation. So far, the studies of patt
Externí odkaz:
https://doaj.org/article/923a542c386240d3a68ec4a774df58e1
Autor:
Michael Hausmann, Charlotte Neitzel, Elizaveta Bobkova, David Nagel, Andreas Hofmann, Tatyana Chramko, Elena Smirnova, Olga Kopečná, Eva Pagáčová, Alla Boreyko, Evgeny Krasavin, Iva Falkova, Dieter W. Heermann, Götz Pilarczyk, Georg Hildenbrand, Felix Bestvater, Martin Falk
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
High-LET (Linear Energy Transfer) particle irradiation as being provided from heavy ion accelerator facilities has an increasing impact on bio-medical research and cancer treatment. Nevertheless, there are a lot of open questions concerning the under
Externí odkaz:
https://doaj.org/article/f3b493e7cd2d4ba9a5b222fc9a1754f7
Autor:
Satyaprakash Pandey, Mona Hajikazemi, Theresa Zacheja, Stephanie Schalbetter, Matthew J. Neale, Jonathan Baxter, Victor Guryev, Andreas Hofmann, Dieter W. Heermann, Stefan A. Juranek, Katrin Paeschke
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-1 (2022)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/bc7ae67fecf847acbcfe1a7504becf9b
Autor:
Michael Hausmann, Martin Falk, Charlotte Neitzel, Andreas Hofmann, Abin Biswas, Theresa Gier, Iva Falkova, Dieter W. Heermann, Georg Hildenbrand
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3636 (2021)
In cancer therapy, the application of (fractionated) harsh radiation treatment is state of the art for many types of tumors. However, ionizing radiation is a “double-edged sword”—it can kill the tumor but can also promote the selection of radio
Externí odkaz:
https://doaj.org/article/8ddb1c993f0e49c49fa3adcad5be362a
Publikováno v:
Nature genetics, 54. Nature Publishing Group
Nucleoprotein complexes play an integral role in genome organization of both eukaryotes and prokaryotes. Apart from their role in locally structuring and compacting DNA, several complexes are known to influence global organization by mediating long-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2cf4f6b5c03c4ca42f53e9cd7218064
https://doi.org/10.1038/s41588-021-00988-8
https://doi.org/10.1038/s41588-021-00988-8
Publikováno v:
The European Physical Journal E. 45
No systematic method exists to derive inter-nucleosomal potentials between nucleosomes along a chromosome consistently across a given genome. Such potentials can yield information on nucleosomal ordering, thermal as well as mechanical properties of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58507c316d96877bb47368657e7a36d2
https://doi.org/10.1140/epje/s10189-022-00185-3
https://doi.org/10.1140/epje/s10189-022-00185-3
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2263 (2018)
DNA double strand breaks (DSB) are the most severe damages in chromatin induced by ionizing radiation. In response to such environmentally determined stress situations, cells have developed repair mechanisms. Although many investigations have contrib
Externí odkaz:
https://doaj.org/article/63951df407d74449800cc64dd235e343
Autor:
Hannes Hahn, Dieter W. Heermann, Michael Hausmann, Charlotte Neitzel, Martin Falk, Olga Kopečná
Publikováno v:
Cancers, Vol 13, Iss 5561, p 5561 (2021)
Cancers
Volume 13
Issue 21
Cancers
Volume 13
Issue 21
DNA double-strand breaks (DSBs), known as the most severe damage in chromatin, were induced in breast cancer cells and normal skin fibroblasts by 2 Gy ionizing photon radiation. In response to DSB induction, phosphorylation of the histone variant H2A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d3df761630fc797df4d05621aa401a
https://www.mdpi.com/2072-6694/13/21/5561
https://www.mdpi.com/2072-6694/13/21/5561