Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Dieter Traue"'
Autor:
Dieter Traue, Ingrid Gerner, Manfred Liebsch, Helena Kandarova, Elisabeth Schmidt, Elke Genschow, Horst Spielmann
Publikováno v:
Alternatives to Laboratory Animals. 33:351-367
During the past decade, several validation studies have been conducted on in vitro methods for discriminating between skin irritating and non-irritating chemicals. The reconstructed human skin models, EpiDerm and EPISKIN, provided the most promising
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11dfd733544c7ab867aaedd464caed9
https://doi.org/10.1177/026119290503300408
https://doi.org/10.1177/026119290503300408
Autor:
Dieter Traue, Martina Remmele, Patricia Uphill, Janet P. McPherson, Horst Spielmann, Christa Barrabas, Susan Wilkins, Hermann-Georg Holzhütter, T. Kaufmann, Christiane Wiemann, Manfred Liebsch
Publikováno v:
Alternatives to laboratory animals : ATLA. 28(3)
In 1996 and 1997, ECVAM supported a formal validation study on in vitro methods for predicting skin corrosivity. Two of the in vitro tests included in the study employed human skin models, the Skin2™ ZK1350 and EPISKIN™ models. In the ECVAM valid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079e108d548229ce0478ce637a677ff5
https://pubmed.ncbi.nlm.nih.gov/25419920
https://pubmed.ncbi.nlm.nih.gov/25419920
Publikováno v:
ALTEX. :165-174
Results are reported using the human epidermis model (EpiDermtrade mark) in a test protocol that was adopted from the method developed by ZEBET for phototoxicity testing with the model Skin2. In the new phototoxicity test the cytotoxicity of test mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35a0ef2b6a30f8c7453dc9162d7c8e10
https://doi.org/10.14573/altex.1997.4.165
https://doi.org/10.14573/altex.1997.4.165
Autor:
Dieter Traue, Manfred Liebsch, Susanne Skolik, Barbara Grune-Wolff, Sigrid Ewe, Joachim Heuer, Horst Spielmann
Publikováno v:
Alternatives to Laboratory Animals. 20:362-367
There is limited availability of reliable and valid information on alternative methods to the use of experimental animals from open access data banks. In 1989, the Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::199e042f40ba2462cbd508813677c3fb
https://doi.org/10.1177/026119299202000303
https://doi.org/10.1177/026119299202000303
Autor:
Claudia Steinhoff, Horst Spielmann, Carine Tornier, Elke Genschow, Kirstin Meyer, Dieter Traue, Martin Rosdy, Bart De Wever, Manfred Liebsch, Helena Kandarova, Elisabeth Schmidt
Publikováno v:
Scopus-Elsevier
Currently, two reconstructed human skin models, EpiDerm™ and EPISKIN™ are being evaluated in an ECVAM skin irritation validation study. A common skin irritation protocol has been developed, differing only in minor technical details for the two mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a814c7db4bdc4db780a65fcd3a27c4e
https://pubmed.ncbi.nlm.nih.gov/16945007
https://pubmed.ncbi.nlm.nih.gov/16945007
Autor:
A. Whittingham, Helena Kandarova, Elisabeth Schmidt, Bart De Wever, Dieter Traue, Marina Remmele, Neil Warren, Martin Rosdy, Robert Guest, Manfred Liebsch, Horst Spielmann, A.O. Gamer, T. Kaufmann, Elke Genschow, Elke Wittmer
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 20(5)
Based on two successfully completed ECVAM validation studies for in vitro skin corrosion testing of chemicals, the National Co-ordinators of OECD Test Guideline Programme endorsed in 2002 two new test guidelines: TG 430 'Transcutaneous Electrical Res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f13d0160d712b93bde2fc23c6fd5be2
https://pubmed.ncbi.nlm.nih.gov/16455230
https://pubmed.ncbi.nlm.nih.gov/16455230
Autor:
Helena, Kandárová, Manfred, Liebsch, Elke, Genschow, Ingrid, Gerner, Dieter, Traue, Birgitta, Slawik, Horst, Spielmann
Publikováno v:
ALTEX. 21(3)
An ECVAM-funded prevalidation study (PV) was conducted during 1999 and 2000 to identify in vitro tests capable of reliably distinguishing between skin irritants (I) and non-irritants (NI) according to European Union risk phrases ("R38" or no classifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37978103613287d1782d0844be7f0ffb
https://pubmed.ncbi.nlm.nih.gov/15329774
https://pubmed.ncbi.nlm.nih.gov/15329774
Autor:
Frank Gerberick, C. Barrabas, M. Liebsch, U. Pfannenbecker, H.-G. Holzhütter, P. Aspin, J. Spieker, Dieter Traue, P. Brantom, Horst Spielmann, W. Diembeck, J. A. Southee, L. Cruse
Publikováno v:
Ersatz-und Ergänzungsmethoden zu Tierversuchen ISBN: 9783211830468
Das von der ECVAM “Task Force Prevalidation” 1994 entwickelte Konzept der Pravalidierung soll verhindern, das neue toxikologische in vitro-Tests in Validierungsstudien unter blinden Bedingungen gepruft werden, bevor ihre Reproduzierbarkeit und Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58fde64c9bd4871f3acf8f9121ef2899
https://doi.org/10.1007/978-3-7091-6760-1_90
https://doi.org/10.1007/978-3-7091-6760-1_90
Publikováno v:
ALTEX. 14(1)
Using cytotoxicity data a new classification procedure is introduced which will allow to allocate chemicals to the four toxicity classes for acute oral toxicity according to EU regulation. Simultaneously, the new procedure allows to reduce animals in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d63c92c66c2620a799d220e1e313f726
https://pubmed.ncbi.nlm.nih.gov/11178482
https://pubmed.ncbi.nlm.nih.gov/11178482
Publikováno v:
ALTEX. 14(4)
Results are reported using the human epidermis model (EpiDermtrade mark) in a test protocol that was adopted from the method developed by ZEBET for phototoxicity testing with the model Skin2. In the new phototoxicity test the cytotoxicity of test mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03f0da826f6691fcbeba5f621caf1eee
https://pubmed.ncbi.nlm.nih.gov/11178502
https://pubmed.ncbi.nlm.nih.gov/11178502