Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dieter Ruppert"'
Autor:
Gerhard Breipohl, Wolfram Schäfer, Hans J. Schramm, Christoph Dr. Meichsner, Stephan Dr Henke, Wolfgang Schramm, Ernst Jaeger, Karl-Peter Rücknagel, Dieter Ruppert, Jutta Dr Hansen, Günther Rieß
Publikováno v:
Biochemical and Biophysical Research Communications. 184:980-985
The active HIV-1 protease is a homodimeric enzyme. A beta-sheet consisting of N- and C-terminal segments provides the main driving force for dimerization of the inactive protomers. Several short peptides with sequences derived from the N- and C-termi
Publikováno v:
Chemische Berichte. 124:2761-2772
Phosphine Alkylidenes, 491). – Chemistry and Stereochemistry of 9,10,19,20-Tetrahydrotetrabenzo[a,c,g,i]cyclododecene and of Some Derivatives Twofold intermolecular C alkylation of the bis-ylide 4 with the dibromide 5 and subsequent hydrolysis yiel
Autor:
Hans-Ludwig Schmidts, Dieter Ruppert, Wolfgang Ulmer, Gabriele Wiemer, Bernward A. Schölkens, Wolfgang Linz
Publikováno v:
Clinical and experimental hypertension (New York, N.Y. : 1993). 18(5)
In male Sprague Dawley rats with left ventricular hypertrophy (LVH) and hypertension induced by aortic constriction (AC) and subsequent myocardial infarction (MI) by occlusion of the left coronary artery the effects of ACE inhibition with ramipril (R
Autor:
Wolfgang Linz, Kleemann Heinz-Werner, Holger Heitsch, Rainer Henning, Wolf Ulrich Nickel, Hansjoerg Urbach, Adalbert Wagner, Dieter Ruppert
Publikováno v:
Journal of medicinal chemistry. 36(19)
Based on the concept of transition-state analogs, a series of nonpeptide renin inhibitors with the new (2S,3R,4S)-2-amino-1-cyclohexyl-3,4-dihydroxy-6-(2-pyridyl)hexane moiety at the C-terminal functionality were synthesized and evaluated for inhibit
Autor:
Klaus Ulrich Weithmann, Dieter Ruppert
Publikováno v:
Life Sciences. 31:2037-2043
The new pyrimido-isoquinoline compound HL 725 is an extremely potent inhibitor of the aggregation of human platelets induced in vitro by ADP, collagen, thrombin and epinephrine. The aggregation induced by 0,5 mM arachidonic acid is inhibited about 50
Autor:
Dieter Ruppert, Ernst Lindner
Publikováno v:
Pharmacology. 24(5)
The contraction of the potassium depolarized pulmonary artery of the guinea pig was diminished by the calcium antagonists nifedipine, gallopamil, diltiazem, verapamil and prenylamine. The drugs are listed here in order of activity. The uptake of 45Ca