Zobrazeno 1 - 6
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pro vyhledávání: '"Dieter Reichert"'
Autor:
Dieter Reichert, Sabine Schütz
Publikováno v:
Biochemical Pharmacology. 35:1271-1275
14C-hexachlorobutadiene (HCBD), a mutagenic and nephrocarcinogenic pollutant, was administered by oral gavage of 100 mg/kg to female rats, and the radioactivity in 24 hr urine pooled. The average amount of radioactivity recovered in urine was 5.4% of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a73d186c8f599a4439c8f079539a97
https://doi.org/10.1016/0006-2952(86)90270-4
https://doi.org/10.1016/0006-2952(86)90270-4
Publikováno v:
Biochemical Pharmacology. 34:499-505
Excretion, covalent binding and metabolism of hexachloro-1,3-butadiene (HCBD), a nephrotoxic and nephrocarcinogenic compound, have been studied in female rats. Seventy-two hours after administration of a single oral dose of 1 mg/kg [14C]HCBD, 5.3% of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c2b399751ec50fabd4ee6a9d687f31
https://doi.org/10.1016/0006-2952(85)90180-7
https://doi.org/10.1016/0006-2952(85)90180-7
Autor:
Dieter Reichert
Publikováno v:
Angewandte Chemie International Edition in English. 20:135-142
Elucidation of the metabolic pathways of foreign compounds in mammalian organisms contributes substantially to the understanding of toxic effects and is therefore a basic component of every risk analysis. The abundance of chemical reactions which tak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cc90321490fde8657224903a3a709de
https://doi.org/10.1002/anie.198101353
https://doi.org/10.1002/anie.198101353
Autor:
Dieter Reichert
Publikováno v:
Angewandte Chemie. 93:135-142
Die Aufklarung der Stoffwechselwege von Fremdstoffen im Korper von Warmblutern tragt wesentlich zum Verstandnis toxischer Wirkungen bei und ist daher elementarer Bestandteil jeder Risikoanalyse. Die Fulle der chemischen Reaktionen, die an den metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff3a54b642a8877a6f67eb14aae1c90d
https://doi.org/10.1002/ange.19810930204
https://doi.org/10.1002/ange.19810930204
Publikováno v:
Carcinogenesis. 5:1411-1420
Dichloroacetylene (DCA) is a by-product of the synthesis of certain chlorinated, aliphatic hydrocarbons (e.g., vinylidene chloride). In a long-term carcinogenicity inhalation study, groups of 30 male and 30 female rats and mice were exposed to DCA va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c22202ceef53e5a72200a3a8f684ab
https://doi.org/10.1093/carcin/5.11.1411
https://doi.org/10.1093/carcin/5.11.1411
Publikováno v:
Carcinogenesis. 7:431-434
The main metabolic pathway of the genotoxic environmental contaminant hexachloro-1,3-butadiene (HCBD) is the direct conjugation reaction with glutathione. To establish structure-effect relationships we studied the mutagenic activity of four S-contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80dfbf23cf438e9b6b1c0482f2d3456
https://doi.org/10.1093/carcin/7.3.431
https://doi.org/10.1093/carcin/7.3.431