Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Dieter Platt"'
Autor:
Dieter Platt
Im höheren Lebensalter nimmt die Zahl der Erkrankungen zu. Oft müssen mehrere Medikamente gleichzeitig eingesetzt werden. Durch die altersbedingten Organveränderungen wird jedoch die Wirkung der Medikamente beeinflußt. Das vorliegende Buch beschr
Publikováno v:
Gerontology. 49:356-365
Background and Purpose: The age-related decline in plasticity of the brain may be one factor underlying the poor functional recovery after stroke. In the present work we tested the hypothesis that the attenuation of neural plasticity could be the res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a9b355222a54ae878d52820ea43a4d
https://doi.org/10.1159/000073763
https://doi.org/10.1159/000073763
Publikováno v:
Journal of Neurochemistry. 65:467-470
Stimuli that evoke seizure are capable of inducing structural changes in the hippocampus. However, late-acting genes related to these changes have not been described. Administration of pentylenetetrazole (PTZ; 50 mg/kg) to rats of various ages evoked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7180e80ebb0e2371a7e17d25f4f86e28
https://doi.org/10.1046/j.1471-4159.1995.65010467.x
https://doi.org/10.1046/j.1471-4159.1995.65010467.x
Publikováno v:
Der Internist. 43:930-940
Mit zunehmendem Alter kommt es bei den meisten physiologischen Parametern zu einem langsamen, kontinuierlichen Ruckgang der im Rahmen von Wachstum und Reifung aufgebauten Reservekapazitaten des Menschen, sodass die Grenzen seiner Leistungsfahigkeit s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aac6e6cbd739bb1dfd5648ce979888a
https://doi.org/10.1007/s00108-002-0594-9
https://doi.org/10.1007/s00108-002-0594-9
Publikováno v:
Intensivmedizin und Notfallmedizin. 39:246-253
Wir berichten uber einen 21-jahrigen Mann, der in suizidaler Absicht ein Minimum von 600 mg Arsentrioxid in kristalliner Form geschluckt hat. Bedingt durch eine etwa siebenstundige Latenz bis zum Behandlungsbeginn kam es zu ausgepragten gastrointesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4bca3fa7bcacbd53bcbb239545452ae
https://doi.org/10.1007/s003900200034
https://doi.org/10.1007/s003900200034
Publikováno v:
Nephron. 90:58-63
Experimental evidence indicates that uraemic patients undergoing haemodialysis are subject to increased oxidative stress. Plasmalogens are a phospholipid subclass found in cell membranes and plasma lipoproteins, which may work as an endogenous antiox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4509303da0f05f619d9b4365b2daff99
https://doi.org/10.1159/000046315
https://doi.org/10.1159/000046315
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 55:B242-B248
The ability of the rodent brain to support plasticity-related phenomena declines with increasing age. Here we investigated the extent to which old rats retain the capacity to initiate transcription for immediate early genes, particularly as it relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a9b73c448ee0350ebe26476e73886f
https://doi.org/10.1093/gerona/55.5.b242
https://doi.org/10.1093/gerona/55.5.b242
Autor:
Dieter Platt, Thorolf Brosche
Publikováno v:
Archives of Gerontology and Geriatrics. 30:139-150
Human skin is not able to biosynthesize gamma-linolenic acid (GLA, 18:3omega6) from the precursor linoleic acid (LA), or arachidonic acid (AA) from dihomo-gamma-linolenic acid (DHGLA). Dietary supplementation with GLA-rich seed oil of borage skips th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9afa4e553822bf60cce504904bdae2
https://doi.org/10.1016/s0167-4943(00)00046-7
https://doi.org/10.1016/s0167-4943(00)00046-7
Publikováno v:
Neuroscience. 94:395-403
The aim of the present study was to assess the age-dependent response of microtubule-associated protein 1B, a plasticity-associated protein deriving from a late gene, following administration of an epileptogenic stimulus. The effect of a single admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e185be1da3999382189536b0f4dbbbab
https://doi.org/10.1016/s0306-4522(99)00204-3
https://doi.org/10.1016/s0306-4522(99)00204-3
Autor:
Dieter Platt
At the beginning of the century the average life span in developed societies was less than 50 years. It is now more than 70 years and will continue to increase in the near future. Aging is a challenge to science and society. There are several theorie