Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dieter Ory"'
Autor:
Lize Cuypers, Jannes Bode, Kurt Beuselinck, Lies Laenen, Klaas Dewaele, Reile Janssen, Arnaud Capron, Yves Lafort, Henry Paridaens, Bertrand Bearzatto, Mathieu Cauchie, Aline Huwart, Jonathan Degosserie, Olivier Fagnart, Yarah Overmeire, Arlette Rouffiange, Ilse Vandecandelaere, Marine Deffontaine, Thomas Pilate, Nicolas Yin, Isabel Micalessi, Sandrine Roisin, Veronique Moons, Marijke Reynders, Sophia Steyaert, Coralie Henin, Elena Lazarova, Dagmar Obbels, François E. Dufrasne, Hendri Pirenne, Raf Schepers, Anaëlle Collin, Bruno Verhasselt, Laurent Gillet, Stijn Jonckheere, Philippe Van Lint, Bea Van den Poel, Yolien Van der Beken, Violeta Stojkovic, Maria-Grazia Garrino, Hannah Segers, Kevin Vos, Maaike Godefroid, Valerie Pede, Friedel Nollet, Vincent Claes, Inge Verschraegen, Pierre Bogaerts, Marjan Van Gysel, Judith Leurs, Veroniek Saegeman, Oriane Soetens, Merijn Vanhee, Gilberte Schiettekatte, Evelyne Huyghe, Steven Martens, Ann Lemmens, Heleen Nailis, Kim Laffineur, Deborah Steensels, Elke Vanlaere, Jérémie Gras, Gatien Roussel, Koenraad Gijbels, Michael Boudewijns, Catherine Sion, Wim Achtergael, Wim Maurissen, Luc Iliano, Marianne Chantrenne, Geert Vanheule, Reinoud Flies, Nicolas Hougardy, Mario Berth, Vanessa Verbeke, Robin Morent, Anne Vankeerberghen, Sébastien Bontems, Kaat Kehoe, Anneleen Schallier, Giang Ho, Kristof Bafort, Marijke Raymaekers, Yolande Pypen, Amelie Heinrichs, Wim Schuermans, Dominique Cuigniez, Salah Eddine Lali, Stefanie Drieghe, Dieter Ory, Marie Le Mercier, Kristel Van Laethem, Inge Thoelen, Sarah Vandamme, Iqbal Mansoor, Carl Vael, Maxime De Sloovere, Katrien Declerck, Elisabeth Dequeker, Stefanie Desmet, Piet Maes, Katrien Lagrou, Emmanuel André
Publikováno v:
Viruses, Vol 14, Iss 6, p 1294 (2022)
From early 2020, a high demand for SARS-CoV-2 tests was driven by several testing indications, including asymptomatic cases, resulting in the massive roll-out of PCR assays to combat the pandemic. Considering the dynamic of viral shedding during the
Externí odkaz:
https://doaj.org/article/9e84aba5685e427f95431c13c8f8b137
Autor:
Igor Fagner Vieira, Dieter Ory, Cindy Casteels, Fernando R. A. Lima, Koen Van Laere, Guy Bormans, Michel Koole
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Method Aim of this study was to automatically select a suitable pseudo-reference brain region for the accurate, non-invasive quantification of neuroinflammation in a rat brain using dynamic [18F]DPA-714 PET imaging. Procedures A supervised c
Externí odkaz:
https://doaj.org/article/dc29051e252f4adc90e234356cf4591c
Autor:
Alessandro Villa, Johnny Vercouillie, Bieneke Janssen, Danielle J. Vugts, Giovanna Pepe, Adriana Maggi, Albert D. Windhorst, Frédéric Dollé, Alexandra Winkeler, Luigi Sironi, Jordi Pedragosa, Dieter Ory, Paolo Gelosa, Annelaure Damont, Elisabetta Vegeto, Benoit Jego, Anna M. Planas, Wissam Beaino, Sandra Laner-Plamberger, Bastian Zinnhardt, Palle Christophersen, Ludwig Aigner, Olof Solin, Uta Funke, Barbara Klein, Linda V. Blomster, Andreas H. Jacobs
Publikováno v:
Theranostics
Villa, A, Klein, B, Janssen, B, Pedragosa, J, Pepe, G, Zinnhardt, B, Vugts, D J, Gelosa, P, Sironi, L, Beaino, W, Damont, A, Dollé, F, Jego, B, Winkeler, A, Ory, D, Solin, O, Vercouillie, J, Funke, U, Laner-Plamberger, S, Blomster, L V, Christophersen, P, Vegeto, E, Aigner, L, Jacobs, A, Planas, A M, Maggi, A & Windhorst, A D 2018, ' Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state ', Theranostics, vol. 8, no. 19, pp. 5400-5418 . https://doi.org/10.7150/thno.25572
Theranostics, 8(19), 5400-5418. Ivyspring International Publisher
Villa, A, Klein, B, Janssen, B, Pedragosa, J, Pepe, G, Zinnhardt, B, Vugts, D J, Gelosa, P, Sironi, L, Beaino, W, Damont, A, Dollé, F, Jego, B, Winkeler, A, Ory, D, Solin, O, Vercouillie, J, Funke, U, Laner-Plamberger, S, Blomster, L V, Christophersen, P, Vegeto, E, Aigner, L, Jacobs, A, Planas, A M, Maggi, A & Windhorst, A D 2018, ' Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state ', Theranostics, vol. 8, no. 19, pp. 5400-5418 . https://doi.org/10.7150/thno.25572
Theranostics, 8(19), 5400-5418. Ivyspring International Publisher
Microglia are potential targets for therapeutic intervention in neurological and neurodegenerative diseases affecting the central nervous system. In order to assess the efficacy of therapies aimed to reduce the tissue damaging activities of microglia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40921a2f7da9ba0fd0e440055c2e505c
https://doi.org/10.7150/thno.25572
https://doi.org/10.7150/thno.25572
Autor:
Jeroen J.M. Hoozemans, Rostislav V Shevchenko, Ger T. Molenaar, Veerle Baekelandt, Sylvie Chalon, Aurélie Doméné, Guy Bormans, Adriana Maggi, Wissam Beaino, Michael Kassiou, Adriaan A. Lammertsma, Uta Funke, Shane M. Wilkinson, Robert C. Schuit, Alessandro Villa, Esther J.M. Kooijman, Johan van den Hoek, Bieneke Janssen, Anke Van der Perren, Mansoor Chishty, Danielle J. Vugts, Albert D. Windhorst, Dieter Ory
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Janssen, B, Vugts, D J, Wilkinson, S M, Ory, D, Chalon, S, Hoozemans, J J M, Schuit, R C, Beaino, W, Kooijman, E J M, Van Den Hoek, J, Chishty, M, Doméné, A, Van Der Perren, A, Villa, A, Maggi, A, Molenaar, G T, Funke, U, Shevchenko, R V, Baekelandt, V, Bormans, G, Lammertsma, A A, Kassiou, M & Windhorst, A D 2018, ' Identification of the allosteric P2X 7 receptor antagonist [ 11 C]SMW139 as a PET tracer of microglial activation ', Scientific Reports, vol. 8, no. 1, 6580 . https://doi.org/10.1038/s41598-018-24814-0
Scientific Reports, 8(1):6580. Nature Publishing Group
Janssen, B, Vugts, D J, Wilkinson, S M, Ory, D, Chalon, S, Hoozemans, J J M, Schuit, R C, Beaino, W, Kooijman, E J M, Van Den Hoek, J, Chishty, M, Doméné, A, Van Der Perren, A, Villa, A, Maggi, A, Molenaar, G T, Funke, U, Shevchenko, R V, Baekelandt, V, Bormans, G, Lammertsma, A A, Kassiou, M & Windhorst, A D 2018, ' Identification of the allosteric P2X 7 receptor antagonist [ 11 C]SMW139 as a PET tracer of microglial activation ', Scientific Reports, vol. 8, no. 1, 6580 . https://doi.org/10.1038/s41598-018-24814-0
Scientific Reports, 8(1):6580. Nature Publishing Group
The P2X7 receptor plays a significant role in microglial activation, and as a potential drug target, the P2X7 receptor is also an interesting target in positron emission tomography. The current study aimed at the development and evaluation of a poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cc71df25ad681f797af725ffc97a78
https://doi.org/10.1038/s41598-018-24814-0
https://doi.org/10.1038/s41598-018-24814-0
Autor:
Bieneke, Janssen, Danielle J, Vugts, Shane M, Wilkinson, Dieter, Ory, Sylvie, Chalon, Jeroen J M, Hoozemans, Robert C, Schuit, Wissam, Beaino, Esther J M, Kooijman, Johan, van den Hoek, Mansoor, Chishty, Aurélie, Doméné, Anke, Van der Perren, Alessandro, Villa, Adriana, Maggi, Ger T, Molenaar, Uta, Funke, Rostislav V, Shevchenko, Veerle, Baekelandt, Guy, Bormans, Adriaan A, Lammertsma, Michael, Kassiou, Albert D, Windhorst
Publikováno v:
Scientific Reports
The P2X7 receptor plays a significant role in microglial activation, and as a potential drug target, the P2X7 receptor is also an interesting target in positron emission tomography. The current study aimed at the development and evaluation of a poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21b81817e8cfd68703e5cd406318447c
https://pubmed.ncbi.nlm.nih.gov/29700413
https://pubmed.ncbi.nlm.nih.gov/29700413
Publikováno v:
Current Pharmaceutical Design. 20:5897-5913
Neuroinflammation is a well-orchestrated, dynamic, multicellular process playing a major role in neurodegenerative disorders. The microglia which make up the innate immune system of the central nervous system are key cellular mediators of neuroinflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165727b62fe230c3b9e924a586a88ebc
https://doi.org/10.2174/1381612820666140613120212
https://doi.org/10.2174/1381612820666140613120212
Autor:
Chris Van den Haute, Meri De Angelis, Anindya Bhattacharya, Rik Gijsbers, Guy Bormans, Andrey Postnov, Zeger Debyser, Michael A. Letavic, Mark E. Schmidt, Jesús Alcázar, Wim Vanduffel, José-Ignacio Andrés, Alfons Verbruggen, Dieter Ory, Xavier Langlois, Koen Van Laere, Caroline Vandeputte, Sofie Celen, Michel Koole
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 57(9)
The P2X7 receptor (P2X7R) orchestrates neuroinflammation, and this is the basis for an increased interest in the development of antagonists inhibiting P2X7R function in the brain. This study provides the preclinical evaluation of 11C-JNJ-54173717, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a68cd125653e1566c114cd9e230cf89
https://pubmed.ncbi.nlm.nih.gov/27199364
https://pubmed.ncbi.nlm.nih.gov/27199364
Autor:
Sofie Celen, Guy Bormans, Michel Koole, Andrey Postnov, Alfons Verbruggen, Cindy Casteels, Dieter Ory, Bart de Laat, Koen Van Laere
Publikováno v:
European journal of nuclear medicine and molecular imaging. 43(1)
PURPOSE: [(18)F]DPA-714 is a radiotracer with high affinity for TSPO. We have characterized the kinetics of [(18)F]DPA-714 in rat brain and evaluated its ability to quantify TSPO expression with PET using a neuroinflammation model induced by unilater
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf9eea139c236b49d25c81d1c9ddd8
https://pubmed.ncbi.nlm.nih.gov/26323575
https://pubmed.ncbi.nlm.nih.gov/26323575
Autor:
Uwe Himmelreich, Guy Bormans, Zeger Debyser, Anna M. Planas, Koen Van Laere, Andrey Postnov, Willy Gsell, Alfons Verbruggen, Cindy Casteels, Sofie Celen, Tom Dresselaers, Dieter Ory
Publikováno v:
Nuclear medicine and biology. 42(10)
OBJECTIVE: The goal of this study was to measure functional and structural aspects of local neuroinflammation induced by intracerebral injection of lipopolysaccharide (LPS) in rats using TSPO microPET imaging with [(18)F]DPA-714, magnetic resonance i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e08e3853578a19cdab3cafbdc44370
https://pubmed.ncbi.nlm.nih.gov/26220690
https://pubmed.ncbi.nlm.nih.gov/26220690