Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Dieter Kube"'
Autor:
Albert Rosenberger, Rachel E. Crossland, Ralf Dressel, Dieter Kube, Daniel Wolff, Gerald Wulf, Heike Bickeböller, Anne Dickinson, Ernst Holler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionData on genomic susceptibility for adverse outcomes after hematopoietic stem cell transplantation (HSCT) for recipients are scarce.MethodsWe performed a genome wide association study (GWAS) to identify genes associated with survival/morta
Externí odkaz:
https://doaj.org/article/28fe5289e59f467c9ac274bb9c1be77a
Autor:
Annekatrin Arlt, Frederike vonBonin, Thorsten Rehberg, Paula Perez‐Rubio, Julia C. Engelmann, Katharina Limm, Sarah Reinke, Christian Dullin, Xueni Sun, Rieke Specht, Markus Maulhardt, Franziska Linke, Gertrude Bunt, Wolfram Klapper, Martina Vockerodt, Jörg Wilting, Tobias Pukrop, Katja Dettmer, Wolfram Gronwald, Peter J. Oefner, Rainer Spang, Dieter Kube
Publikováno v:
Molecular Oncology, Vol 14, Iss 3, Pp 571-589 (2020)
Macrophages (Mφ) are abundantly present in the tumor microenvironment and may predict outcome in solid tumors and defined lymphoma subtypes. Mφ heterogeneity, the mechanisms of their recruitment, and their differentiation into lymphoma‐promoting,
Externí odkaz:
https://doaj.org/article/d0ac1ea38d6f4b968a3e384e01c44384
Autor:
Maren Feist, Philipp Schwarzfischer, Paul Heinrich, Xueni Sun, Judith Kemper, Frederike von Bonin, Paula Perez-Rubio, Franziska Taruttis, Thorsten Rehberg, Katja Dettmer, Wolfram Gronwald, Jörg Reinders, Julia C. Engelmann, Jan Dudek, Wolfram Klapper, Lorenz Trümper, Rainer Spang, Peter J. Oefner, Dieter Kube
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Metabolic rewiring of cancer cells can be driven by both extrinsic and intrinsic factors. Here the authors show that microenvironmental factors induce metabolic rewiring of B-cell lymphoma through activation of STAT3 and NF-ΚB resulting in upregulat
Externí odkaz:
https://doaj.org/article/10dedebdb6144adc9af992f5ae10844d
Autor:
Franziska Taruttis, Maren Feist, Phillip Schwarzfischer, Wolfram Gronwald, Dieter Kube, Rainer Spang, Julia C. Engelmann
Publikováno v:
BioTechniques, Vol 62, Iss 2, Pp 53-61 (2017)
Gene expression measurements are typically performed on a fixed-weight aliquot of RNA, which assumes that the total number of transcripts per cell stays nearly constant across all conditions. In cases where this assumption does not hold (e.g., when c
Externí odkaz:
https://doaj.org/article/602042c995e04590800392c5a2c6b6ff
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224062 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0197162.].
Externí odkaz:
https://doaj.org/article/dfb36a814a56465ebc1b7eb56a53646b
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197162 (2018)
BACKGROUND:Pipeline comparisons for gene expression data are highly valuable for applied real data analyses, as they enable the selection of suitable analysis strategies for the dataset at hand. Such pipelines for RNA-Seq data should include mapping
Externí odkaz:
https://doaj.org/article/9aa73c4bd4a74d97a006e9f9a7cc2233
Autor:
Antje Isernhagen, Dörthe Malzahn, Elena Viktorova, Leslie Elsner, Sebastian Monecke, Frederike von Bonin, Markus Kilisch, Janne Marieke Wermuth, Neele Walther, Yesilda Balavarca, Christiane Stahl‐Hennig, Michael Engelke, Lutz Walter, Heike Bickeböller, Dieter Kube, Gerald Wulf, Ralf Dressel
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 11, Pp 1480-1502 (2015)
Abstract The MHC class I chain‐related molecule A (MICA) is a highly polymorphic ligand for the activating natural killer (NK)‐cell receptor NKG2D. A single nucleotide polymorphism causes a valine to methionine exchange at position 129. Presence
Externí odkaz:
https://doaj.org/article/10306a23c43f40c0b4441e4d3a488884
Autor:
Emily Heath, Noelia Begue-Pastor, Sridhar Chaganti, Debbie Croom-Carter, Claire Shannon-Lowe, Dieter Kube, Regina Feederle, Henri-Jacques Delecluse, Alan B Rickinson, Andrew I Bell
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002697 (2012)
Epstein-Barr virus (EBV), a lymphomagenic human herpesvirus, colonises the host through polyclonal B cell-growth-transforming infections yet establishes persistence only in IgD⁺ CD27⁺ non-switched memory (NSM) and IgD⁻ CD27⁺ switched memory (
Externí odkaz:
https://doaj.org/article/ed4f30f2a0934f5cad9fcf65c29bad6a
PDF - 1109K, Blood and lymphatic vessel density in experimental BL2B95 tumors treated with IB in the CAM model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf7fc4c7b7a480eb514ab352b36d1231
https://doi.org/10.1158/1535-7163.22501314
https://doi.org/10.1158/1535-7163.22501314
Burkitt lymphoma is a rare malignancy arising from B cells. Current chemotherapeutic regimens achieve excellent overall survival rates in children, but less impressive rates in adults. There are cases with poor outcome caused by toxic effects of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c8b73e34119355bbcb116313f4cce04
https://doi.org/10.1158/1535-7163.c.6536748.v1
https://doi.org/10.1158/1535-7163.c.6536748.v1