Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dieter Jenne"'
Autor:
Mathangi Janakiraman, Alexei Leliavski, Jeeva Varadarajulu, Dieter Jenne, Gurumoorthy Krishnamoorthy
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Current effective therapies for autoimmune diseases rely on systemic immunomodulation that broadly affects all T and/or B cell responses. An ideal therapeutic approach would combine autoantigen-specific targeting of both T and B cell effecto
Externí odkaz:
https://doaj.org/article/30973964cd2c4447b73df3c03454c454
Autor:
Maximilian Ebert, Uwe Jerke, Claudia Eulenberg-Gustavus, Lovis Kling, Dieter Jenne, Marieluise Kirchner, Philipp Mertins, Markus Bieringer, Saban Elitok, Kai-Uwe Eckardt, Adrian Schreiber, Alan D. Salama, Ralph Kettritz
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
Background Antineutrophil cytoplasmic autoantibody–associated (ANCA-associated) vasculitidies (AAV) are life-threatening systemic autoimmune conditions. ANCAs directed against proteinase 3 (PR3) or myeloperoxidase (MPO) bind their cell surface-pres
Externí odkaz:
https://doaj.org/article/9c5f2d75f15f4b508c8edb2149fdceb8
Autor:
Iris Marti Fernandez, Caterina Macrini, Markus Krumbholz, Paul J. Hensbergen, Agnes L. Hipgrave Ederveen, Stephan Winklmeier, Atay Vural, Asli Kurne, Dieter Jenne, Frits Kamp, Lisa Ann Gerdes, Reinhard Hohlfeld, Manfred Wuhrer, Tania Kümpfel, Edgar Meinl
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Autoantibodies to myelin oligodendrocytes glycoprotein (MOG) are found in a fraction of patients with inflammatory demyelination and are detected with MOG-transfected cells. While the prototype anti-MOG mAb 8-18C5 and polyclonal anti-MOG responses fr
Externí odkaz:
https://doaj.org/article/0625c6d85031465797b02e7849f31245
Autor:
Anne-Sophie Lamort, Yveline Hamon, Cezary Czaplewski, Artur Gieldon, Seda Seren, Laurent Coquet, Fabien Lecaille, Adam Lesner, Gilles Lalmanach, Francis Gauthier, Dieter Jenne, Brice Korkmaz
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4747 (2019)
Cysteine cathepsin C (CatC) is a ubiquitously expressed, lysosomal aminopeptidase involved in the activation of zymogens of immune-cell-associated serine proteinases (elastase, cathepsin G, proteinase 3, neutrophil serine proteinase 4, lymphocyte gra
Externí odkaz:
https://doaj.org/article/b71b6cbf4a634b4da3fc611805a7a33d
Akademický článek
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Publikováno v:
Journal of Immunological Methods. 80:25-32
Immunoprecipitates formed in conventional electroimmunoassays were solubilized by brief immersion of the agarose gels in sodium dodecylsulfate. The proteins were then transferred to nitrocellulose sheets by electroblotting. The blotted proteins were
Autor:
Keith K. Stanley, Dieter Jenne
Publikováno v:
Biochemistry. 26:6735-6742
The S-protein/vitronectin gene was isolated from a human genomic DNA library, and its sequence of about 5.3 kilobases including the adjacent 5' and 3' flanking regions was established. Alignment of the genomic DNA nucleotide sequence and the cDNA seq
Publikováno v:
Bioscience Reports. 5:649-658
Assembly of the terminal C5b-C9 complement components into the cytolytic C5b-9 complex is accompanied by exposure of characteristic neoantigens on the macromolecule. We report the production and characterization of mouse monoclonal antibodies to C9-d
Publikováno v:
Thrombosis Research. 38:401-412
Complement S-protein is known to function as an inhibitor of the terminal complement sequence (Bhakdi, S. and Tranum-Jensen, J., Biochim. Biophys. Acta 737, 343, 1983). We here report that the S-protein may also play a functional role in haemostasis.