Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Dieter Heber"'
Publikováno v:
Molecules, Vol 5, Iss 1, Pp 19-32 (2000)
Reaction of 4-hydroxy-6-methyl-2-pyrone (1a) as well as 4-hydroxy-6-methyl-2(1H)-pyridones (1b-d) with arylmethylene malononitriles or arylmethylene methyl cyanoacetates (2a-h) leads to the formation of the very stable 5,6-fused bicyclic 2-amino-4Hpy
Externí odkaz:
https://doaj.org/article/ab2382bf95604a50bec80a0351f68691
Autor:
Tamara N. Steinhauer, Inga Zebothsen, Dieter Heber, Doris Marko, Matthias Weide, Bernd Clement, Christopher Meier, Dana zur Nieden, Ulrich Wolschendorf, Georg Aichinger, Ulrich Girreser, Ilka Kaltefleiter, Lars Stenzel
Publikováno v:
ChemMedChem. 11:2155-2170
The synthesis of various new structures of a library of 11-substituted 6-amino-11,12-dihydrobenzo[c]phenanthridines (BP) and 11-substituted 6-aminobenzo[c]phenanthridines (BP-D) is presented. These structures, further synthetic modifications, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9973aa1ed401d961a0fcd00ad9e855d
https://doi.org/10.1002/cmdc.201600199
https://doi.org/10.1002/cmdc.201600199
Autor:
Lars Stenzel, Bernd Clement, Christopher Meier, Tamara N. Steinhauer, Dieter Heber, Daniel Längle, Ulrich Girreser
Publikováno v:
Chemistry - A European Journal. 21:6668-6672
We herein describe a facile and versatile synthetic route to the tetracyclic system of 6-substituted 5,6-dihydro-11H-pyrido[3,2-i]-1-azacarbazoles with promising anticancer properties. These derivatives are built up by an elegant one-step base-cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f183779b6c62720a56fd40815abe695b
https://doi.org/10.1002/chem.201500156
https://doi.org/10.1002/chem.201500156
Autor:
Booma Ramassamy, Dieter Heber, Ulrich Girreser, Ulrich Wolschendorf, Ullvi Bluhm, Bernd Clement, Jean-Luc Boucher
Publikováno v:
Journal of Heterocyclic Chemistry. 52:24-39
Aryl methyl ketones can be easily converted to 1-aryl-2-dimethylaminomethylpropenones that are known as interesting lead structures for drug development. By reaction of these enone Mannich bases with benzamidines, a series of new 2-aryl-5-aroyl-3,4,5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92c6b0e0d2c9ad443efa7f832686ae28
https://doi.org/10.1002/jhet.1925
https://doi.org/10.1002/jhet.1925
1 H, 13 C and 15 N NMR spectral analysis of substituted 1,2,3,4-tetrahydro-pyrido[1,2-a ]pyrimidines
Publikováno v:
Magnetic Resonance in Chemistry. 51:714-721
The NMR spectroscopic data of a series of thirty-four 3-acylpyrido[1,2-a]pyrimidinium salts are analyzed, which were prepared as either perchlorates or chlorides. Methyl group substituted 3-aroyltetrahydropyrido[1,2-a]pyrimidines with the methyl subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4e8eec4841eb9e0e056cd3632818790
https://doi.org/10.1002/mrc.4005
https://doi.org/10.1002/mrc.4005
Autor:
Dieter Heber, Bernd Clement, Christopher Meier, Ulrich Girreser, Joscha Kotthaus, Lars Stenzel
Publikováno v:
Tetrahedron. 68:9105-9112
Based on the 6-aminobenzo[ c ]phenanthridines, a compound class showing noteworthy antitumor activity, an efficient one-step synthesis consisting of a base-catalyzed condensation of 2 equiv of 4-methylpyridine-3-carbonitrile and various aldehydes cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db4267721a83b9c9542ad1b10106e3a5
https://doi.org/10.1016/j.tet.2012.08.047
https://doi.org/10.1016/j.tet.2012.08.047
Publikováno v:
Synthesis. 2010:2017-2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76bf7fd8961ddc14fe33cfd7c17ae3c3
https://doi.org/10.1055/s-0029-1218758
https://doi.org/10.1055/s-0029-1218758
Autor:
Michel Lepoivre, Thanh Lam, Ullvi Bluhm, Jean-Luc Boucher, Uwe Dr. Buss, Dieter Heber, Mojgan Rostaie-Gerylow, Ulrich Wolschendorf, Bernd Clement, Friederike Friedrich, Ulrich Girreser
Publikováno v:
European Journal of Medicinal Chemistry. 44:2877-2887
A series of new 3-aroylpyrido[1,2-a]pyrimidines were synthesized from aryl methyl ketones in a simple two-step procedure and evaluated as nitric oxide synthases (NOS) inhibitors. In order to perform a structure-activity relationship study, different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54e10dd283198828c02dc1690b7705c
https://doi.org/10.1016/j.ejmech.2008.12.007
https://doi.org/10.1016/j.ejmech.2008.12.007
Publikováno v:
Zeitschrift für Naturforschung B. 64:662-668
A synthetic access to novel cinnamoamides 6 was discovered by chance and explored following a two-step route. Compounds 3 were available from 6-amino-1,3-dimethyluracil (1) by acylation using benzoyl chlorides 2 and subsequently converted to 2-cyano-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::781edb3004c890fa07808eda5b6931b0
https://doi.org/10.1515/znb-2009-0611
https://doi.org/10.1515/znb-2009-0611
Autor:
Daniel S. Laengle, Ulrich Girreser, Dieter Heber, Christopher Meier, Lars Stenzel, Bernd Clement, Tamara N. Steinhauer
Publikováno v:
ChemInform. 46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b8dde8fd15b8092004a7bc340ce44d6
https://doi.org/10.1002/chin.201536189
https://doi.org/10.1002/chin.201536189