Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Dieter Greif"'
Publikováno v:
Current Organocatalysis. 8:238-248
Background:: Chiral β-hydroxy esters and α-substituted β-hydroxy esters represent versatile building blocks for pheromones, β-lactam antibiotics and 1,2- or 1,3-aminoalcohols. Objective:: Synthesis of versatile α-substituted β-keto esters and t
Autor:
Christoph Hauser, Gloria Ruiz-Gómez, Robert Wodtke, David Bauer, Alan Wong, Sandra Hauser, Steffen Fischer, Markus Pietsch, Friedrich-Alexander Ludwig, Johanna Pufe, Elisabeth Jäckel, Jens Pietzsch, Dieter Greif, Reik Löser, Martin Lohse, M. Teresa Pisabarro
Publikováno v:
Journal of Medicinal Chemistry. 61:4528-4560
Transglutaminase 2 (TGase 2)-catalyzed transamidation represents an important post-translational mechanism for protein modification with implications in physiological and pathophysiological conditions, including fibrotic and neoplastic processes. Con
Autor:
Dieter Greif, Christian Trapp, Marek J. Pecyna, Corinna Herrmann, Annett Fuchs, Kateřina Barková, Martin Hofrichter
Publikováno v:
Molecular Catalysis. 509:111578
Enantiomerically pure α-substituted β-hydroxyesters are important chiral building blocks for ligands, auxiliaries and β-lactam antibiotics. A two-step chemo-enzymatic procedure using lipase as biocatalyst is an efficient way to synthesize such pro
Autor:
Robert, Wodtke, Christoph, Hauser, Gloria, Ruiz-Gómez, Elisabeth, Jäckel, David, Bauer, Martin, Lohse, Alan, Wong, Johanna, Pufe, Friedrich-Alexander, Ludwig, Steffen, Fischer, Sandra, Hauser, Dieter, Greif, M Teresa, Pisabarro, Jens, Pietzsch, Markus, Pietsch, Reik, Löser
Publikováno v:
Journal of medicinal chemistry. 61(10)
Transglutaminase 2 (TGase 2)-catalyzed transamidation represents an important post-translational mechanism for protein modification with implications in physiological and pathophysiological conditions, including fibrotic and neoplastic processes. Con
Publikováno v:
Zeitschrift für Chemie. 28:345-352
Most important methods for the synthesis of enaminothioketones — A) sulfurization of enaminoketones; B) from β-halogeno-as well as β-alkoxyvinylmethin-immonium salts and alkali sulfides or -thiosulfates; C) from 1,2-dithiolium and isothiazolium s
Autor:
Roland Ruscher, Luis F. Spitta, Andrea Arenz, Klaus-Dieter Greif, Christa Baumstark-Khan, Susanne Bogner, Christine E. Hellweg, Ulrich Giesen
Publikováno v:
Advances in Space Research. 39:1056-1065
Within the next decades, an increasing number of human beings will be brought into space to carry out technical and scientific tasks. There, they will be exposed simultaneously to combined stimuli, especially microgravity and radiation. In the endeav
Publikováno v:
International Journal of Radiation Biology. 82:59-67
To investigate the dependence of bystander effects on linear energy transfer (LET) in the low dose region.The single-ion microbeam of the Physikalisch-Technische Bundesanstalt (PTB) was used to irradiate confluent primary human skin fibroblasts. Cell
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 136:1763-1779
A new approach to trifluoromethyl substituted butenolides and their thioanalogues is described starting from 2-fluoro-3-trifluoromethylfurans and -thiophenes, respectively. The reaction sequence includes three steps – nucleophilic displacement reac
Publikováno v:
Monatshefte für Chemie/Chemical Monthly. 132:929-945
The single fluorine atom of 2-fluoro-3-trifluoromethylfurans and -thiophenes can be readily replaced by various nucleophiles. Depending on the substituent pattern, certain products obtained upon nucleophilic substitution with benzyl alcohols are susc
Publikováno v:
Zeitschrift für Chemie. 29:57-59