Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Dieter Glebe"'
Autor:
Hongtao Liu, Dariusz Zakrzewicz, Kamil Nosol, Rossitza N. Irobalieva, Somnath Mukherjee, Rose Bang-Sørensen, Nora Goldmann, Sebastian Kunz, Lorenzo Rossi, Anthony A. Kossiakoff, Stephan Urban, Dieter Glebe, Joachim Geyer, Kaspar P. Locher
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Cellular entry of the hepatitis B and D viruses (HBV/HDV) requires binding of the viral surface polypeptide preS1 to the hepatobiliary transporter Na+-taurocholate co-transporting polypeptide (NTCP). This interaction can be blocked by bulevi
Externí odkaz:
https://doaj.org/article/f9ddf8c868954a5d843a6783bfb948e5
Autor:
Motswedi Anderson, Bonolo B. Phinius, Basetsana K. Phakedi, Mbatshi Mudanga, Lynnette N. Bhebhe, Girlie N. Tlhabano, Patience Motshosi, Tsholofelo Ratsoma, Kabo Baruti, Gorata Mpebe, Wonderful T. Choga, Richard Marlink, Dieter Glebe, Jason T. Blackard, Sikhulile Moyo, Anna Kramvis, Simani Gaseitsiwe
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
AimThis study aimed to determine the kinetics of occult hepatitis B virus infections (OBI) among people with HIV (PWH).MethodsThe study used archived plasma samples from longitudinal HIV natural history studies. We identified new OBI cases and assess
Externí odkaz:
https://doaj.org/article/a1fb6e1bfe774ca3bcb77efb42001557
Autor:
Pierre Khalfi, Zoé Denis, Joe McKellar, Giovanni Merolla, Carine Chavey, José Ursic-Bedoya, Lena Soppa, Leonora Szirovicza, Udo Hetzel, Jeremy Dufourt, Cedric Leyrat, Nora Goldmann, Kaku Goto, Eloi Verrier, Thomas F Baumert, Dieter Glebe, Valérie Courgnaud, Damien Gregoire, Jussi Hepojoki, Karim Majzoub
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012060 (2024)
The recent discovery of Hepatitis D (HDV)-like viruses across a wide range of taxa led to the establishment of the Kolmioviridae family. Recent studies suggest that kolmiovirids can be satellites of viruses other than Hepatitis B virus (HBV), challen
Externí odkaz:
https://doaj.org/article/ada71d4cf9dd4a64980a7c9aa774c4a5
Autor:
Trodia Zitha, Chien-Yu Chen, Hatim Mudawi, Waleed Hussein, Maowia Mukhtar, Mazin Shigidi, Mohamed Elamin Awad Yousif, Mohammed Ahmed Ali, Dieter Glebe, Anna Kramvis
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Hepatitis C virus (HCV) is a global public health problem, with ~ 11 million people in Africa infected. There is incomplete information on HCV in Sudan, particularly in haemodialysis patients, who have a higher prevalence compared
Externí odkaz:
https://doaj.org/article/8906a79713334cb39b9250afcd1a5f2d
Autor:
Katja Giersch, Paulina Perez-Gonzalez, Lennart Hendricks, Nora Goldmann, Jonathan Kolbe, Lennart Hermanussen, Jan-Hendrick Bockmann, Tassilo Volz, Annika Volmari, Lena Allweiss, Joerg Petersen, Dieter Glebe, Marc Lütgehetmann, Maura Dandri
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100673- (2023)
Background & Aims: Pegylated interferon alpha (pegIFNα) is commonly used for the treatment of people infected with HDV. However, its mode of action in HDV-infected cells remains elusive and only a minority of people respond to pegIFNα therapy. Here
Externí odkaz:
https://doaj.org/article/01d54f34c762458ab95d9601864425ef
Autor:
Nora Helmrich, Martin Roderfeld, Anne Baier, Anita Windhorst, Diran Herebian, Ertan Mayatepek, Christian Dierkes, Matthias Ocker, Dieter Glebe, Bruno Christ, Yuri Churin, Karuna Irungbam, Elke Roeb
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 4, Pp 1041-1055 (2022)
Background & Aims: The endocannabinoid system is involved in the modulation of inflammatory, fibrotic, metabolic, and carcinogenesis-associated signaling pathways via cannabinoid receptor (CB)1 and CB2. We hypothesized that the pharmacologic antagoni
Externí odkaz:
https://doaj.org/article/d09d8c8611ec48a3bb15ab6b0b480739
Autor:
Felix Lehmann, Heiko Slanina, Martin Roderfeld, Elke Roeb, Jonel Trebicka, John Ziebuhr, Wolfram H. Gerlich, Christian G. Schüttler, Bernhard Schlevogt, Dieter Glebe
Publikováno v:
Viruses, Vol 15, Iss 4, p 838 (2023)
Chronic hepatitis B virus (HBV) infection is a global health threat. Mutations in the surface antigen of HBV (HBsAg) may alter its antigenicity, infectivity, and transmissibility. A patient positive for HBV DNA and detectable but low-level HBsAg in p
Externí odkaz:
https://doaj.org/article/6cee633209324ff7a9655f20ecb318ea
Autor:
Yuri Churin, Karuna Irungbam, Christoph S. Imiela, David Schwarz, Hans-Joachim Mollenkopf, Uta Drebber, Margarete Odenthal, Oleg Pak, Magdalena Huber, Dieter Glebe, Martin Roderfeld, Elke Roeb
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 383-394 (2021)
Background and Aims: A histopathological hallmark of chronic hepatitis B virus (HBV) infection is the presence of ground glass hepatocytes (GGHs). GGHs are liver cells that exhibit eosinophilic, granular, glassy cytoplasm in light microscopy and are
Externí odkaz:
https://doaj.org/article/5d731b4ed5db4b48a5a43b963f5c152e
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 2264-2275 (2021)
Hepatitis B virus (HBV) is a DNA virus with a complex life cycle that includes a reverse transcription step. HBV is poorly sensed by the immune system and frequently establishes persistent infection that can cause chronic infection, the leading cause
Externí odkaz:
https://doaj.org/article/205e452875b2468fbd2cfb195e701371
Autor:
Michael Kirstgen, Kira Alessandra Alicia Theresa Lowjaga, Simon Franz Müller, Nora Goldmann, Felix Lehmann, Sami Alakurtti, Jari Yli-Kauhaluoma, Dieter Glebe, Joachim Geyer
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Current treatment options against hepatitis B and D virus (HBV/HDV) infections have only limited curative effects. Identification of Na+/taurocholate co-transporting polypeptide (NTCP) as the high-affinity hepatic receptor for both viruses i
Externí odkaz:
https://doaj.org/article/b5edf866c0b64b18948a6735dc0b00e5