Výsledky vyhledávání - "Dieter Gelbmann"

The pneumococcal eukaryotic-type serine/threonine protein kinase StkP co-localizes with the cell division apparatus and interacts with FtsZ in vitro

Autor: Carmen Giefing, Kira E. Jelencsics, Dieter Gelbmann, Eszter Nagy, Beatrice M. Senn

Publikováno v: Microbiology. 156:1697-1707

The importance of serine/threonine phosphorylation in signalling and regulation of gene expression in prokaryotes has been widely recognized. Driven by our interest in StkP (the pneumococcal serine/threonine kinase homologue) for vaccine development,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9526a6e02f7740cd0af725036435738
https://doi.org/10.1099/mic.0.036335-0

Zobrazit plný text záznamu

Composition of the ANTIGENome of Helicobacter pylori defined by human serum antibodies

Autor: Andreas Meinke, Lars Engstrand, Dieter Gelbmann, Birgit Noiges, Tamás Henics, Alexander von Gabain, Eszter Nagy, Duc Bui Minh, Zoltan B. Kovacs, Sonja Prustomersky, Manfred Berger, Ulrike Stierschneider, Martin Storm

Publikováno v: Vaccine. 27:3251-3259

Helicobacter pylori is the most prevalent human pathogen and although, it remains silent in most individuals for lifetime, colonization may develop into severe gastric and duodenal conditions. Rapidly developing resistance to antibiotic treatment urg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f0a6215f95aecf2df4abab0e08641b
https://doi.org/10.1016/j.vaccine.2009.01.066

Zobrazit plný text záznamu

Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies

Autor: Markus Hanner, Birgitta Henriques-Normark, Eszter Nagy, Dieter Gelbmann, Duc Bui Minh, Beatrice M. Senn, Tamás Henics, Alexander von Gabain, Mats Kalin, André Habel, Andreas Meinke, Michael Schunn, Åke Örtqvist, Urban Lundberg, Carmen Giefing

Publikováno v: The Journal of Experimental Medicine

Pneumococcus is one of the most important human pathogens that causes life-threatening invasive diseases, especially at the extremities of age. Capsular polysaccharides (CPSs) are known to induce protective antibodies; however, it is not feasible to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aaf6cff3f8ea45ce2ee3c2ccc1c6730
https://doi.org/10.1084/jem.20071168

Zobrazit plný text záznamu

High-Affinity Binding of the Staphylococcal HarA Protein to Haptoglobin and Hemoglobin Involves a Domain with an Antiparallel Eight-Stranded β-Barrel Fold

Autor: Agnieszka Dryla, Walter Koppensteiner, Eszter Nagy, Dieter Gelbmann, Andreas Meinke, Markus Hanner, Annaliesa S. Anderson, Alexander von Gabain, Bernd Hoffmann, Robert Konrat, Carmen Giefing

Publikováno v: Journal of Bacteriology. 189:254-264

Iron scavenging from the host is essential for the growth of pathogenic bacteria. In this study, we further characterized two staphylococcal cell wall proteins previously shown to bind hemoproteins. HarA and IsdB harbor homologous ligand binding doma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e948e74c07b2ee8c94a6a63c1e13b3
https://doi.org/10.1128/jb.01366-06

Zobrazit plný text záznamu

Identification of a novel iron regulated staphylococcal surface protein with haptoglobin-haemoglobin binding activity

Autor: Dieter Gelbmann, Eszter Nagy, Agnieszka Dryla, Alexander von Gabain

Publikováno v: Molecular Microbiology. 49:37-53

Staphylococcus aureus is an extremely adaptable pathogen causing a wide variety of infections. Staphylococcal surface proteins that directly interact with host extracellular proteins greatly contribute to virulence and are involved in adhesion, immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6eaa1c7031ac847bd4ffda0b122dd61b
https://doi.org/10.1046/j.1365-2958.2003.03542.x

Zobrazit plný text záznamu

Concomitant Determination of Absolute Values of Cellular Protein Amounts, Synthesis Rates, and Turnover Rates by Quantitative Proteome Profiling

Autor: Josef Gotzmann, Rolf Schulte-Hermann, Editha Bayer, Wolfgang Mikulits, Susanne Vejda, Dieter Gelbmann, Christopher Gerner

Publikováno v: Molecular & Cellular Proteomics. 1:528-537

Two-dimensional gel electrophoresis of protein fractions isolated from (35)S-radiolabeled cells provides qualitative information on intracellular amounts, (35)S incorporation rates, protein modifications, and subcellular localizations of up to thousa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1909f975e3f4908c0c747d5f2ca16a28
https://doi.org/10.1074/mcp.m200026-mcp200

Zobrazit plný text záznamu

The Fas-induced Apoptosis Analyzed by High Throughput Proteome Analysis

Autor: Wilfried Bursch, Rolf Schulte-Hermann, Christopher Gerner, Editha Bayer, Josef Gotzmann, Ulrike Fröhwein, Dieter Gelbmann

Publikováno v: Journal of Biological Chemistry. 275:39018-39026

The fate of cytosolic proteins was studied during Fas-induced cell death of Jurkat T-lymphocytes by proteome analysis. Among 1000 spots resolved in two-dimensional gels, comparison of control versus apoptotic cells revealed that the signal intensity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9908bbab6ebc497cf428bd6bddd49b90
https://doi.org/10.1074/jbc.m006495200

Zobrazit plný text záznamu

Monoclonal antibodies targeting different cell wall antigens of group B streptococcus mediate protection in both Fc-dependent and independent manner

Autor: Dieter Gelbmann, Zehra Visram, Dieter J. Reinscheid, Markus Hanner, Beatrice M. Senn, Eszter Nagy, Alexander von Gabain, Urban Lundberg, Andreas Meinke, Jan Sinzinger, Heike Boisvert, Christina Neubauer

Publikováno v: Vaccine. 29(24)

Group B streptococcus remains an important neonatal pathogen in spite of widely adopted intrapartum antibiotic administration; therefore immune prophylaxis for GBS infections is highly warranted. In passive immunization and lethal challenge studies w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c586f80732600e22f6355c669201e87f
https://pubmed.ncbi.nlm.nih.gov/21496467

Zobrazit plný text záznamu

Novel conserved group A streptococcal proteins identified by the antigenome technology as vaccine candidates for a non-M protein-based vaccine

Autor: Birgit Noiges, Alexander von Gabain, Eszter Nagy, Tamás Henics, Duc Bui Minh, Andrea Fritzer, Carlos A. Guzmán, Dieter Gelbmann, Kai Schulze, Beatrice M. Senn, Markus Hanner, John Goodacre, Andreas Meinke

Publikováno v: Infection and immunity. 78(9)

Group A streptococci (GAS) can cause a wide variety of human infections ranging from asymptomatic colonization to life-threatening invasive diseases. Although antibiotic treatment is very effective, when left untreated,Streptococcus pyogenesinfection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5c6681668568567c1c2e45efa4d883
https://pubmed.ncbi.nlm.nih.gov/20624906

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání