Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Dieter G. Weiss"'
Autor:
Tareck Rharass, Margareta Lantow, Adam Gbankoto, Dieter G. Weiss, Daniela Panáková, Stéphanie Lucas
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-16 (2017)
Abstract Background Improving the neuronal yield from in vitro cultivated neural progenitor cells (NPCs) is an essential challenge in transplantation therapy in neurological disorders. In this regard, Ascorbic acid (AA) is widely used to expand neuro
Externí odkaz:
https://doaj.org/article/79bb18274df2483580c348cc8ec360a5
Publikováno v:
International Journal of Developmental Neuroscience. 48:9-17
BCL-2 is a multifunctional protein involved in the regulation of apoptosis, cell cycle progression and neural developmental processes. Its function in the latter process is not well understood and needs further elucidation. Therefore, we characterize
Publikováno v:
Spuren: Erzeugung des Dagewesenen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da6d5b8878fc7f0f0d9c560726175e61
https://doi.org/10.1515/9783110478389-005
https://doi.org/10.1515/9783110478389-005
Autor:
Tareck Rharass, Heiko Lemcke, Daniela Panáková, Margareta Lantow, Dieter G. Weiss, Sergei A. Kuznetsov
Publikováno v:
The Journal of Biological Chemistry
Background: Dissociation of the Wnt/β-catenin pathway effector Dishevelled from its complex with nucleoredoxin is a redox-sensitive process, yet the ROS sources remain elusive. Results: Mitochondrial Ca2+ influx stimulates endogenous ROS production
Autor:
Alexandra Gramowski-Voss, Zafiroula Georgoussi, Dieter G. Weiss, Dirk Tourwé, A. W. Lipkowski, Bart Vandormael, Olaf Schröder, Piotr Kosson, Danai-Dionysia Fourla
Publikováno v:
Journal of Medicinal Chemistry. 54:7848-7859
Novel dermorphin tetrapeptides are described in which Tyr1 is replaced by Dmt1, where d-Ala2 and Gly4 are N-methylated, and where Phe3-Gly4 residue is substituted by the constrained Aba3-Gly4 peptidomimetic. Most of these peptidic ligands displayed b
Autor:
Juliane Flossdorf, Dieter G. Weiss, Margareta Lantow, Alexandra Gramowski, Elke Dopp, Ludwig Jonas, Qamar Rahman, Kunal Bhattacharya, Dietmar Schiffmann
Publikováno v:
Environmental Health Perspectives
Background Nanomaterials are extensively used in industry and daily life, but little is known about possible health effects. An intensified research regarding toxicity of nanomaterials is urgently needed. Several studies have demonstrated that nanopa
Autor:
Dieter G. Weiss, Guenter W. Gross, Timothy J. Shafer, Andrew F.M. Johnstone, Olaf H.-U. Schroeder, Alexandra Gramowski
Publikováno v:
NeuroToxicology
NeuroToxicology; Vol 31
NeuroToxicology; Vol 31
Microelectrode arrays (MEAs) have been in use over the past decade and a half to study multiple aspects of electrically excitable cells. In particular, MEAs have been applied to explore the pharmacological and toxicological effects of numerous compou
Autor:
V. N. Nuriev, Dieter G. Weiss, Nikolai V. Zyk, Sergei A. Kuznetsov, Olga N. Zefirova, E. V. Nurieva, Nikolay S. Zefirov
Publikováno v:
Moscow University Chemistry Bulletin. 64:219-223
Four (2R,3S)-N-benzoylphenylisoserine esters with substituted bicyclo[3.3.1]nonanes are synthesized. The compounds are found to be unable to promote tubulin polymerization, but cause a weak tubulin aggregation (oligomerization).
Autor:
Dieter G. Weiss, Sergei A. Kuznetsov, Heiko Lemcke, E. V. Nurieva, Olga N. Zefirova, Dmitrii V. Shishov, Andrei A. Ivanov, Nikolay S. Zefirov
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5091-5094
Several adamantane-based taxol mimetics were synthesized and found to be cytotoxic at micromolar concentrations and to cause tubulin aggregation. The extent of the aggregation is maximal for N-benzoyl-(2R,3S)-phenylisoseryloxyadamantane (5) and is ve
Publikováno v:
European Journal of Cell Biology. 87:1-88