Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Dieter E, Jenne"'
Autor:
Marta Casal, Moura, Gwen E, Thompson, Darlene R, Nelson, Lynn A, Fussner, Amber M, Hummel, Dieter E, Jenne, Daniel, Emerling, Fernando C, Fervenza, Cees G M, Kallenberg, Carol A, Langford, W Joseph, McCune, Peter A, Merkel, Paul A, Monach, Philip, Seo, Robert F, Spiera, E William, St Clair, Steven R, Ytterberg, John H, Stone, William H, Robinson, Ulrich, Specks
Publikováno v:
Arthritis & Rheumatology. 75:748-759
Proteinase 3 (PR3) is the major antigen for anti-neutrophil cytoplasmic antibodies (ANCAs) in the systemic autoimmune vasculitis, granulomatosis with polyangiitis (GPA). PR3 anti-neutrophil cytoplasmic antibodies (PR3-ANCAs) recognize different epito
Autor:
Jérôme Granel, Brice Korkmaz, Dalila Nouar, Stefanie A. I. Weiss, Dieter E. Jenne, Roxane Lemoine, Cyrille Hoarau
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Granulomatosis with polyangiitis (GPA) is a rare but serious necrotizing auto-immune vasculitis. GPA is mostly associated with the presence of Anti-Neutrophil Cytoplasmic Antibody (ANCA) targeting proteinase 3 (PR3-ANCA), a serine protease contained
Externí odkaz:
https://doaj.org/article/6b62382e37b34723b8f923559f6d54e8
Autor:
Yuan-Ping Pang, Marta Casal Moura, Gwen E. Thompson, Darlene R. Nelson, Amber M. Hummel, Dieter E. Jenne, Daniel Emerling, Wayne Volkmuth, William H. Robinson, Ulrich Specks
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Mutants of a catalytically inactive variant of Proteinase 3 (PR3)—iPR3-Val103 possessing a Ser195Ala mutation relative to wild-type PR3-Val103—offer insights into how autoantigen PR3 interacts with antineutrophil cytoplasmic antibodies (ANCAs) in
Externí odkaz:
https://doaj.org/article/315a254bfbd1410fbcbda94f11de70d8
Autor:
Achim Krüger, Chris D. Hermann, Dieter E. Jenne, Oliver Soehnlein, Percy Knolle, Ihsan Ekin Demir, Katja Steiger, Daniel Häußler, Jan Böttcher, Olga Prokopchuk, Celina Eckfeld, Benjamin Schoeps
Supplementary Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5960aa13a293dcfe330c0fada2d2867f
https://doi.org/10.1158/0008-5472.22428897
https://doi.org/10.1158/0008-5472.22428897
Autor:
Achim Krüger, Chris D. Hermann, Dieter E. Jenne, Oliver Soehnlein, Percy Knolle, Ihsan Ekin Demir, Katja Steiger, Daniel Häußler, Jan Böttcher, Olga Prokopchuk, Celina Eckfeld, Benjamin Schoeps
Supplementary Figures S1 - S9 Table S1 and S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780a73b5875ce4e4ef57b96f3b69499e
https://doi.org/10.1158/0008-5472.22428888.v1
https://doi.org/10.1158/0008-5472.22428888.v1
Autor:
Achim Krüger, Chris D. Hermann, Dieter E. Jenne, Oliver Soehnlein, Percy Knolle, Ihsan Ekin Demir, Katja Steiger, Daniel Häußler, Jan Böttcher, Olga Prokopchuk, Celina Eckfeld, Benjamin Schoeps
Tumor-derived protein tissue inhibitor of metalloproteinases-1 (TIMP1) correlates with poor prognosis in many cancers, including highly lethal pancreatic ductal adenocarcinoma (PDAC). The noncanonical signaling activity of TIMP1 is emerging as one ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ae45c252202ed60f7d6bcd78d55c4a7
https://doi.org/10.1158/0008-5472.c.6513189.v1
https://doi.org/10.1158/0008-5472.c.6513189.v1
Autor:
Moritz Leppkes, Christian Maueröder, Sebastian Hirth, Stefanie Nowecki, Claudia Günther, Ulrike Billmeier, Susanne Paulus, Mona Biermann, Luis E. Munoz, Markus Hoffmann, Dane Wildner, Andrew L. Croxford, Ari Waisman, Kerri Mowen, Dieter E. Jenne, Veit Krenn, Julia Mayerle, Markus M. Lerch, Georg Schett, Stefan Wirtz, Markus F. Neurath, Martin Herrmann, Christoph Becker
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Pancreatitis often develops as a consequence of ductal obstruction. Here, the authors show that bicarbonate ions initiate the release of neutrophil extracellular traps (NETs) that form pancreatic ductal aggregates and occlude the ducts, thereby drivi
Externí odkaz:
https://doaj.org/article/8649b3e8245b4fed8b30b9961760de6f
Autor:
Nina Kessler, Susanne F. Viehmann, Calvin Krollmann, Karola Mai, Katharina M. Kirschner, Hella Luksch, Prasanti Kotagiri, Alexander M.C. Böhner, Dennis Huugen, Carina C. de Oliveira Mann, Simon Otten, Stefanie A.I. Weiss, Thomas Zillinger, Kristiyana Dobrikova, Dieter E. Jenne, Rayk Behrendt, Andrea Ablasser, Eva Bartok, Gunther Hartmann, Karl-Peter Hopfner, Paul A. Lyons, Peter Boor, Angela Rösen-Wolff, Lino L. Teichmann, Peter Heeringa, Christian Kurts, Natalio Garbi
Publikováno v:
Journal of Experimental Medicine. 219
Autor:
Percy A. Knolle, Olga Prokopchuk, Achim Krüger, Chris D. Hermann, Jan P. Böttcher, Celina Eckfeld, Ihsan Ekin Demir, Dieter E. Jenne, Daniel Häußler, Oliver Soehnlein, Benjamin Schoeps, Katja Steiger
Publikováno v:
Cancer Res. 81, 3568-3579 (2021)
Tumor-derived protein tissue inhibitor of metalloproteinases-1 (TIMP1) correlates with poor prognosis in many cancers, including highly lethal pancreatic ductal adenocarcinoma (PDAC). The noncanonical signaling activity of TIMP1 is emerging as one ba
Autor:
Simone Mader, Lena Bergmann, Michaela Smolle, Dieter E. Jenne, Stephan Winklmeier, Henri G. Franquelim, Edgar Meinl, Reinhard Hohlfeld, Caterina Macrini, Tania Kümpfel, Melania Spadaro, Atay Vural, Ramona Gerhards, Stefan F. Lichtenthaler
Publikováno v:
Brain
Brain 144(8), 2375-2389 (2021). doi:10.1093/brain/awab105
Brain 144(8), 2375-2389 (2021). doi:10.1093/brain/awab105
Antibodies to myelin oligodendrocyte glycoprotein (MOG-Abs) define a distinct disease entity. Here we aimed to understand essential structural features of MOG required for recognition by autoantibodies from patients. We produced the N-terminal part o