Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Dieter Blottner"'
Autor:
Britt Schoenrock, Paul E. Muckelt, Maria Hastermann, Kirsten Albracht, Robert MacGregor, David Martin, Hans-Christian Gunga, Michele Salanova, Maria J. Stokes, Martin B. Warner, Dieter Blottner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Muscle function is compromised by gravitational unloading in space affecting overall musculoskeletal health. Astronauts perform daily exercise programmes to mitigate these effects but knowing which muscles to target would optimise effectiven
Externí odkaz:
https://doaj.org/article/97be173728144a41a218ead6e223f88c
Autor:
Dieter Blottner, Manuela Moriggi, Gabor Trautmann, Sandra Furlan, Katharina Block, Martina Gutsmann, Enrica Torretta, Pietro Barbacini, Daniele Capitanio, Joern Rittweger, Ulrich Limper, Pompeo Volpe, Cecilia Gelfi, Michele Salanova
Publikováno v:
Antioxidants, Vol 13, Iss 4, p 432 (2024)
Long-duration mission (LDM) astronauts from the International Space Station (ISS) (>180 ISS days) revealed a close-to-normal sarcolemmal nitric oxide synthase type-1 (NOS1) immunoexpression in myofibers together with biochemical and quantitative qPCR
Externí odkaz:
https://doaj.org/article/266feed64e8245ea8265d265b6510f62
Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-20 (2023)
Abstract The circadian clock regulates cellular and molecular processes in mammals across all tissues including skeletal muscle, one of the largest organs in the human body. Dysregulated circadian rhythms are characteristic of aging and crewed spacef
Externí odkaz:
https://doaj.org/article/b2e28f74f50b4fcab79a8e3467d7bb2c
Autor:
Paul E. Muckelt, Martin B. Warner, Tom Cheliotis-James, Rachel Muckelt, Maria Hastermann, Britt Schoenrock, David Martin, Robert MacGregor, Dieter Blottner, Maria Stokes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The assessment of muscle health is of paramount importance, as the loss of muscle mass and strength can affect performance. Two non-invasive tools that have been found to be useful in this are the MyotonPRO and rehabilitative ultrasound imag
Externí odkaz:
https://doaj.org/article/7a53ad0aaa254ebea35af0f23564760d
Autor:
Dieter Blottner, Manuela Moriggi, Gabor Trautmann, Maria Hastermann, Daniele Capitanio, Enrica Torretta, Katharina Block, Joern Rittweger, Ulrich Limper, Cecilia Gelfi, Michele Salanova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 4095 (2023)
The molecular mechanisms of skeletal muscle adaptation to spaceflight are as yet not fully investigated and well understood. The MUSCLE BIOPSY study analyzed pre and postflight deep calf muscle biopsies (m. soleus) obtained from five male Internation
Externí odkaz:
https://doaj.org/article/1f856570ea3543e9b39d9b9a6aeb3df8
Autor:
Martin Schubert, Andreas Pelz, Gabor Trautmann, Katharina Block, Sandra Furlan, Martina Gutsmann, Siegfried Kohler, Pompeo Volpe, Dieter Blottner, Andreas Meisel, Michele Salanova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15052 (2022)
Accelerated postsynaptic remodelling and disturbance of neuromuscular transmission are common features of autoimmune neurodegenerative diseases. Homer protein isoform expression, crosslinking activity and neuromuscular subcellular localisation are st
Externí odkaz:
https://doaj.org/article/1b8cb145b774430c85d8e5f610ce66e7
Autor:
Pietro Barbacini, Dieter Blottner, Daniele Capitanio, Gabor Trautmann, Katharina Block, Enrica Torretta, Manuela Moriggi, Michele Salanova, Cecilia Gelfi
Publikováno v:
Cells, Vol 11, Iss 13, p 2120 (2022)
Physical inactivity or prolonged bed rest (BR) induces muscle deconditioning in old and young subjects and can increase the cardiovascular disease risk (CVD) with dysregulation of the lipemic profile. Nutritional interventions, combining molecules su
Externí odkaz:
https://doaj.org/article/2d354869ec7b4705b3e7182dda9a3a75
Autor:
Alireza Basti, Müge Yalçin, David Herms, Janina Hesse, Ouda Aboumanify, Yin Li, Zita Aretz, Josefin Garmshausen, Rukeia El-Athman, Maria Hastermann, Dieter Blottner, Angela Relógio
Publikováno v:
BMJ Open Sport & Exercise Medicine, Vol 7, Iss 1 (2021)
Objectives In this study, we investigated daily fluctuations in molecular (gene expression) and physiological (biomechanical muscle properties) features in human peripheral cells and their correlation with exercise performance.Methods 21 healthy part
Externí odkaz:
https://doaj.org/article/8a41bc736916486b8ffc89002d93fcd0
Autor:
Dieter Blottner, Gabor Trautmann, Sandra Furlan, Guido Gambara, Katharina Block, Martina Gutsmann, Lian-Wen Sun, Paul F. Worley, Luisa Gorza, Martina Scano, Paola Lorenzon, Imre Vida, Pompeo Volpe, Michele Salanova
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 75 (2021)
The molecular mechanisms of skeletal muscle atrophy under extended periods of either disuse or microgravity are not yet fully understood. The transition of Homer isoforms may play a key role during neuromuscular junction (NMJ) imbalance/plasticity in
Externí odkaz:
https://doaj.org/article/fed4fe2771064e6894c12b6c3bbcde91
Autor:
Coralie Arc-Chagnaud, Guillaume Py, Théo Fovet, Rémi Roumanille, Rémi Demangel, Allan F. Pagano, Pierre Delobel, Stéphane Blanc, Bernard J. Jasmin, Dieter Blottner, Michele Salanova, Mari-Carmen Gomez-Cabrera, José Viña, Thomas Brioche, Angèle Chopard
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Understanding the molecular pathways involved in the loss of skeletal muscle mass and function induced by muscle disuse is a crucial issue in the context of spaceflight as well as in the clinical field, and development of efficient countermeasures is
Externí odkaz:
https://doaj.org/article/169a25d5eb1c4ea5995972c01900836e