Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Dieter Binder"'
Publikováno v:
Tetrahedron. 56:3697-3701
A rapid route was developed to afford ethynyl-substituted imidazole derivatives which served as key compounds for aryl–alkynyl-coupling reactions. Addition of mono-silylated acetylene to O-protected oximes was carried out in the absence of Lewis ac
Publikováno v:
Monatshefte für Chemie / Chemical Monthly. 130:645-651
The synthesis of the thiophene analogue of dazoxiben – one of the most selective TXA 2-synthase inhibitors – and its derivatization to a chlorinated, more lipophilic product is described. The ethylenoxy moiety was introduced via nucleophilic arom
Publikováno v:
Monatshefte für Chemie / Chemical Monthly. 129:887-896
The synthesis of three thiophene analogues of Flosulide – a potent and selective inhibitor of cyclooxygenase subtype 2 (COX-2) – is described. Utilizing combined Friedel-Crafts acylation and alkylation of 2-chlorothiophene, simplified procedures
Publikováno v:
Journal of Heterocyclic Chemistry. 35:923-926
Three isomeric substituted thienoimidazothiazoles were synthesized as thiophene analogs of the immune modulator TILOMISOL, by cyclizing appropriate β-oxothioethers of thienoimidazoles. In contrast to the benzene analog no intermediates were observed
Publikováno v:
Synthesis. 1978:60-62
Publikováno v:
Tetrahedron Letters. 43:177-179
Both enantiomers of the conformationally restricted nicotine analogue 7-(3-pyridyl)-1-azabicyclo[2.2.1]heptane were prepared in a convenient, asymmetric synthetic route.
Publikováno v:
ChemInform. 22
Publikováno v:
ChemInform. 22
Publikováno v:
ChemInform. 30
The synthesis of three thiophene analogues of Flosulide – a potent and selective inhibitor of cyclooxygenase subtype 2 (COX-2) – is described. Utilizing combined Friedel-Crafts acylation and alkylation of 2-chlorothiophene, simplified procedures
Publikováno v:
ChemInform. 30
Three isomeric substituted thienoimidazothiazoles were synthesized as thiophene analogs of the immune modulator TILOMISOL, by cyclizing appropriate β-oxothioethers of thienoimidazoles. In contrast to the benzene analog no intermediates were observed