Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Dieter, Staab"'
Autor:
Markus Stoeckli, Han Wang, Dieter Staab, Frederic Grandjean, Fabian Sesterhenn, Christian Opitz
Publikováno v:
SLAS Technology, Vol 29, Iss 6, Pp 100216- (2024)
Tracking chemical reactions by measuring incurred mass shifts upon successful binding is a direct and attractive alternative to existing assays based on chemical tags. Traditional methods use liquid chromatography-mass spectrometry (LC-MS), and becau
Externí odkaz:
https://doaj.org/article/6b9a61c0727044d1b88808c950235e50
Autor:
Ole Kristian Greiner-Tollersrud, Máté Krausz, Vincent Boehler, Aikaterini Polyzou, Maximilian Seidl, Ambra Spahiu, Zeinab Abdullah, Katarzyna Andryka-Cegielski, Felix Immunuel Dominick, Katrin Huebscher, Andreas Goschin, Cristian R. Smulski, Eirini Trompouki, Regina Link, Hilmar Ebersbach, Honnappa Srinivas, Martine Marchant, Georgios Sogkas, Dieter Staab, Cathrine Vågbø, Danilo Guerini, Sebastian Baasch, Eicke Latz, Gunther Hartmann, Philippe Henneke, Roger Geiger, Xiao P. Peng, Bodo Grimbacher, Eva Bartok, Ingrun Alseth, Max Warncke, Michele Proietti
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114899- (2024)
Summary: Although adenosine deaminase 2 (ADA2) is considered an extracellular ADA, evidence questions the physiological relevance of this activity. Our study reveals that ADA2 localizes within the lysosomes, where it is targeted through modifications
Externí odkaz:
https://doaj.org/article/f6e14d70f0b648c3aca83261512b83d8
Publikováno v:
CHIMIA, Vol 68, Iss 3 (2014)
A device was built for matrix deposition in mass spectrometric imaging. This spray-type instrument requires no user interaction other than providing the spray solution and selecting the pre-defined or custom-built method. Robustness was achieved by u
Externí odkaz:
https://doaj.org/article/9fb69046b11b4b89a99224e0c9a55624
Publikováno v:
CHIMIA, Vol 67, Iss 4 (2013)
Externí odkaz:
https://doaj.org/article/2a99630d97534a8e98f1d1fa486dcac9
Autor:
Katrin Hübscher, Eirini Trompouki, Danilo Guerini, Roger Geiger, Ole K. Greiner-Tollersrud, Honnappa Srinivas, Sebastian Baasch, Eva Bartok, Hilmar Ebersbach, Salvatore Raieli, Jan Ole Olsen, Martine Marchant, Bodo Grimbacher, Vincent Boehler, Georg Kochs, Aikaterini Polyzou, Regina Link, Cristian R. Smulski, Gunther Hartmann, Máté Krausz, Michele Proietti, Dieter Staab, Maximilian Seidl, Johanna Schepp, Philipp Henneke, Max Warncke
Deficiency of adenosine deaminase 2 (DADA2) is a severe, congenital syndrome, which manifests with hematologic, immunologic and inflammatory pathologies. DADA2 is caused by biallelic mutations in ADA2, but the function of ADA2, and the mechanistic li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26a38fc6bbd8be9ab969f0fdbf4f90d2
https://doi.org/10.1101/2020.06.21.162990
https://doi.org/10.1101/2020.06.21.162990
Autor:
Dieter Staab, Markus Stoeckli
Publikováno v:
Journal of the American Society for Mass Spectrometry. 26:911-914
The new open-source software and hardware matrix deposition device named iMatrixSpray was optimized and specified for homogeneity, reproducibility, and sensitivity in MS imaging experiments. The results confirm the design claims, with the device deli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04cb9e192f4450bb45514ad64cceb1a
https://doi.org/10.1007/s13361-015-1099-9
https://doi.org/10.1007/s13361-015-1099-9
Autor:
Ursula Junker, Brendan Prideaux, Markus Stoeckli, Douglas C. Bauer, Alex Odermatt, Stéphanie Boudon, Dieter Staab, Gregory Morandi
Publikováno v:
Journal of the American Society for Mass Spectrometry. 25:1803-1809
Mass spectrometry imaging (MSI) was applied to samples from mouse skin and from a human in vitro 3D skin model in order to assess its suitability in the context of photosafety evaluation. MSI proved to be a suitable method for the detection of the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531309ef67c9df6597fbd01498d65827
https://doi.org/10.1007/s13361-014-0947-3
https://doi.org/10.1007/s13361-014-0947-3
Autor:
Julia Reichwald, Dieter Staab, Matthias Staufenbiel, Domenico Ammaturo, Marie-Josephine Runser, Markus Stoeckli, Karl-Heinz Wiederhold, Ulrich Furrer, Anton Neuenschwander, Simone Danner, Anne-Lise Jaton, Ulf Neumann, Dorothee Abramowski, Heinrich Rueeger
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 327:411-424
Human beta-amyloid precursor protein (APP) transgenic mice are commonly used to test potential therapeutics for Alzheimer's disease. We have characterized the dynamics of beta-amyloid (Abeta) generation and deposition following gamma-secretase inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1849a85bb7feb92e5418ae37a984390d
https://doi.org/10.1124/jpet.108.140327
https://doi.org/10.1124/jpet.108.140327
Publikováno v:
International Journal of Mass Spectrometry. 260:195-202
The determination of the compound distribution in laboratory animal tissue in early development is a standard process in pharmaceutical research. While this information is traditionally obtained by means of whole-body autoradiography using radiolabel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62aeeb799b9079e56ec29164ea9e3778
https://doi.org/10.1016/j.ijms.2006.10.007
https://doi.org/10.1016/j.ijms.2006.10.007
Publikováno v:
Mechanisms of Ageing and Development. 126:177-185
In biomedical research, the discovery of new biomarkers and new drugs demands analytical techniques with high sensitivity together with increased throughput. The possibility to localize or to follow changes in organisms at the molecular level by imag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af51669cd3da911161b59fc31a35c91e
https://doi.org/10.1016/j.mad.2004.09.032
https://doi.org/10.1016/j.mad.2004.09.032