Behavioural outcomes of subthalamic stimulation and medical therapy versus medical therapy alone for Parkinson's disease with early motor complications (EARLYSTIM trial): secondary analysis of an open-label randomised trial

Autor: Eugénie Lhommée, Lars Wojtecki, Virginie Czernecki, Karsten Witt, Franziska Maier, Lisa Tonder, Lars Timmermann, Thomas D Hälbig, Fanny Pineau, Franck Durif, Tatiana Witjas, Marcus Pinsker, Maximilian Mehdorn, Friederike Sixel-Döring, Andreas Kupsch, Rejko Krüger, Saskia Elben, Stephan Chabardès, Stéphane Thobois, Christine Brefel-Courbon, Fabienne Ory-Magne, Jean-Marie Regis, David Maltête, Anne Sauvaget, Jörn Rau, Alfons Schnitzler, Michael Schüpbach, Carmen Schade-Brittinger, Gunther Deuschl, Jean-Luc Houeto, Paul Krack, Velina Negovanska, Marie-Laure Welter, Jean-Christophe Corvol, Yves Agid, Soledad Navarro, Niklaus Meier, Andreas Hartmann, Helke Hesekamp, Philippe Cornu, Bettina Möller, Adelheid Nebel, Jan Raethjen, Karina Knudsen, Jens Volkmann, Daniela Falk, Steffen Paschen, Ingo Meister, Jens Kuhn, Kerstin Donner, Josef Kessler, Michael Barbe, Gereon Fink, Mohammad Maarouf, Andrea Kühn, Bianca Müller, Katharina Faust, Doreen Gruber, Gerd-H. Schneider, Eric Seigneuret, Pierre Pollak, Valerie Fraix, Andrea Kistner, Olivier Rascol, Christophe Arbus, Lola Danet, Patrick Chaynes, Stefan J. Groiss, Christian Hartmann, Martin Südmeyer, Mahnaz Partowinia-Peters, Jan Vesper, Severine Ledily, Philippe Damier, Sylvie Raoul, Claudia Trenkwalder, Wenke Richter-Dreske, Tobias Wächter, Daniel Weiss, Alexandro Eusebio, Jean Philippe Azulay, Gustavo Polo, Serge Pinto, Johannes Levin, Stephanie Dornier, Fredy Pene, Delphine Hourton, Mathieu Quintin, Cecile Hoffart-Jourdain, Helene Brocvielle, Kerstin Balthasar, Meryem Stein, Susanne Harnisch, Alexander Reuss, Behnaz Aminossadati, Christian Nasemann, Wolfgang Oertel, Benoit Bataille, Dieter Hellwig, Alireza Gharabaghi, Florian Amtage, Patrick Mertens, Manja Kloss, Bart Post, Hans Speelman

Publikováno v: The Lancet Neurology
The Lancet Neurology, 2018, 17 (3), pp.223-231. ⟨10.1016/S1474-4422(18)30035-8⟩
The Lancet Neurology, Elsevier, 2018, 17 (3), pp.223-231. ⟨10.1016/S1474-4422(18)30035-8⟩
The Lancet Neurology, Vol. 17, No 3 (2018) pp. 223-231
ResearcherID
Lancet Neurology
Lancet Neurology, Elsevier, 2018, 17 (3), pp.223-231. ⟨10.1016/S1474-4422(18)30035-8⟩

Although subthalamic stimulation is a recognised treatment for motor complications in Parkinson's disease, reports on behavioural outcomes are controversial, which represents a major challenge when counselling candidates for subthalamic stimulation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f93fa38cc982bdaa7311c1798631f1
https://pubmed.ncbi.nlm.nih.gov/29452675

Skin complications in deep brain stimulation for Parkinson’s disease: frequency, time course, and risk factors

Autor: Friederike Sixel-Döring, Christoph Kappus, Claudia Trenkwalder, Dieter Hellwig

Publikováno v: Acta Neurochirurgica. 152:195-200

Deep brain stimulation (DBS) has been recognized as an efficacious treatment for movement disorders. Its beneficial effects however may be lost due to skin complications such as erosions or infections over the implanted foreign material. We sought to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4058fca006f481e5f7116ddc7a668fe5
https://doi.org/10.1007/s00701-009-0490-3

Volumetric Image Guidance for Motor Cortex Stimulation: Integration of Three-dimensional Cortical Anatomy and Functional Imaging

Autor: Madjid Samii, Ramin Shahidi, Alireza Gharabaghi, Dieter Hellwig, Hans-Joachim Freund, Steffen K. Rosahl, Christoph Schrader

Publikováno v: Operative Neurosurgery. 57:114-120

OBJECTIVE: Epidural electrical stimulation of the motor cortex is a promising treatment option in patients with intractable pain. Varying rates of success in long-term pain relief have been attributed to inaccurate positioning of the electrode array,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbe26f0b60db2cc0df3918af74855d8
https://doi.org/10.1227/01.neu.0000164385.42652.9e

Image-Guided Motor Cortex Stimulation in Patients with Central Pain

Autor: Helmut Bertalanffy, Jochen Rohlfs, Dieter Hellwig, Ulrich Sure, Thomas Riegel, Wuttipong Tirakotai, Gharabaghi A

Publikováno v: min - Minimally Invasive Neurosurgery. 47:273-277

According to recent clinical data, motor cortex stimulation (MCS) is an alternative treatment for central pain syndromes. We present our minimally invasive technique of image guidance for the placement of the motor cortex-stimulating electrode and as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4768806e38674e03a507464bc0223c
https://doi.org/10.1055/s-2004-830092

Neuroendoscopic stent procedure in obstructive hydrocephalus due to both foramina of monro occluding craniopharyngioma: technical note

Autor: Wuttipong Tirakotai, Thomas Riegel, Dieter Hellwig, Dirk Michael Schulte, Helmut Bertalanffy

Publikováno v: Surgical Neurology. 61:293-296

Background The development of various neuroendoscopic surgical instruments has offered more options for endoscopic procedures in the treatment of intraventricular tumors. Not only tumor biopsy or tumor resection but also restoration of an obstructed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6f3d23d6c09b1b45734033cc4ab236
https://doi.org/10.1016/s0090-3019(03)00424-5