Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Dieter, Brömme"'
Autor:
Lili Wang, Shan Wang, Xuan Dai, Gaiyue Yue, Jiyuan Yin, Tianshu Xu, Hanfen Shi, Tianyuan Liu, Zhanhong Jia, Dieter Brömme, Shuofeng Zhang, Dongwei Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Osteoporosis becomes a global public health concern due to its rising prevalence and substantial impact on life quality. Salvia miltiorrhiza Bunge (Salviae Miltiorrhizae Radix et Rhizoma, SM) has been firstly recorded in Shen Nong’s Herbal Classic,
Externí odkaz:
https://doaj.org/article/67fef2a76ed342029a76991d8b62361e
Autor:
Preety Panwar, Jacob Bastholm Olesen, Galia Blum, Jean-Marie Delaisse, Kent Søe, Dieter Brömme
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cathepsin K (CatK), an essential collagenase in osteoclasts (OCs), is a potential therapeutic target for the treatment of osteoporosis. Using live-cell imaging, we monitored the bone resorptive behaviour of OCs during dose-dependent inhibiti
Externí odkaz:
https://doaj.org/article/92cb3c72ac144f1391fde56b99a57085
Autor:
Lili Wang, Rufeng Ma, Yubo Guo, Jing Sun, Haixia Liu, Ruyuan Zhu, Chenyue Liu, Jun Li, Lin Li, Beibei Chen, Liping Sun, Jinfa Tang, Dandan Zhao, Fangfang Mo, Jianzhao Niu, Guangjian Jiang, Min Fu, Dieter Brömme, Dongwei Zhang, Sihua Gao
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/0644698b158140998d4fd4d788fb5d58
Autor:
Lili Wang, Rufeng Ma, Yubo Guo, Jing Sun, Haixia Liu, Ruyuan Zhu, Chenyue Liu, Jun Li, Lin Li, Beibei Chen, Liping Sun, Jinfa Tang, Dandan Zhao, Fangfang Mo, Jianzhao Niu, Guangjian Jiang, Min Fu, Dieter Brömme, Dongwei Zhang, Sihua Gao
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Purpose: This study is designed to explore whether Fructus ligustri lucidi (FLL) exhibits antioxidant effect in ovariectomized (OVX) rats, and to identify the signaling pathway involved in this process.Methods: OVX rats were treated with FLL aqueous
Externí odkaz:
https://doaj.org/article/4e63eaeae1d84d3ba0a949d0aa9fccb6
Autor:
Simon Law, Preety Panwar, Jody Li, Adeleke H Aguda, Andrew Jamroz, Rafael V C Guido, Dieter Brömme
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186869 (2017)
Cathepsin K (CatK) is a cysteine protease that plays an important role in mammalian intra- and extracellular protein turnover and is known for its unique and potent collagenase activity. Through studies on the mechanism of its collagenase activity, s
Externí odkaz:
https://doaj.org/article/b8e1c750eb84499aa628571486395374
Autor:
Geoffrey Bailleul, Amanda Kravtzoff, Alix Joulin-Giet, Fabien Lecaille, Valérie Labas, Hervé Meudal, Karine Loth, Ana-Paula Teixeira-Gomes, Florence B Gilbert, Laurent Coquet, Thierry Jouenne, Dieter Brömme, Catherine Schouler, Céline Landon, Gilles Lalmanach, Anne-Christine Lalmanach
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161573 (2016)
Defensins are frontline peptides of mucosal immunity in the animal kingdom, including birds. Their resistance to proteolysis and their ensuing ability to maintain antimicrobial potential remains questionable and was therefore investigated. We have sh
Externí odkaz:
https://doaj.org/article/bc8a541167664d988c81bca07a5c5e8b
Autor:
Patrick Graff, Jenny Wilzopolski, Anne Voss, Travis M. Blimkie, January Weiner, Olivia Kershaw, Preety Panwar, Tillie Hackett, Dieter Brömme, Lucie Loyal, Andreas Thiel, Dieter Beule, Robert E.W. Hancock, Achim D. Gruber, Wolfgang Bäumer, Sarah Hedtrich
The development of atopic dermatitis (AD) in infancy, and subsequent allergic rhinitis, food allergies, and asthma in later childhood, is known as the atopic march. The mechanism is largely unknown, yet the course of disease indicates the contributio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::792f17a055b2f3ca2fad21b828610332
https://doi.org/10.1101/2022.01.17.22269397
https://doi.org/10.1101/2022.01.17.22269397
Autor:
Ariana Costa-Mugica, Ana Elsa Batista- Gonzalez, Diadelis Mondejar, Yosdel Soto-López, Victor Brito-Navarro, Ana Maria Vázquez, Dieter Brömme, Claudina Zaldívar-Muñoz, Alexis Vidal-Novoa, Ana Mara de Oliveira e Silva, Jorge Mancini-Filho
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 48, Iss 1, Pp 31-37 (2012)
LDL oxidation and oxidative stress are closely related to atherosclerosis. Therefore, natural antioxidants have been studied as promising candidates. In the present study, the LDL oxidation inhibition activity of bioactive compounds from Halimeda inc
Externí odkaz:
https://doaj.org/article/c515005edd33440186de92686a824a50
Publikováno v:
Chinese Journal of Osteoporosis; 2023, Vol. 29 Issue 1, p95-98, 4p
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Elastin plays an important role in maintaining blood vessel integrity. Proteolytic degradation of elastin in the vascular system promotes the development of atherosclerosis, including blood vessel calcification. Cysteine cathepsins have been implicat