Developing forebrain synapses are uniquely vulnerable to sleep loss.

Autor: Gay SM; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Chartampila E; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Lord JS; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Grizzard S; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Maisashvili T; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Ye M; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Barker NK; University of North Carolina Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Mordant AL; University of North Carolina Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Mills CA; University of North Carolina Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Herring LE; University of North Carolina Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Diering GH; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Carolina Institute for Developmental Disabilities, Carrboro, NC 27510.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Oct 29; Vol. 121 (44), pp. e2407533121. Date of Electronic Publication: 2024 Oct 23.

Analysis of hepatic lentiviral vector transduction; implications for preclinical studies and clinical gene therapy protocols.

Autor: Hu P; Gene Therapy Center, University of North Carolina at Chapel Hill, 27599 Chapel Hill, North Carolina, USA.; These authors contributed equally., Hao Y; Department of Biostatistics, University of North Carolina at Chapel Hill, 27599 Chapel Hill, North Carolina, USA.; These authors contributed equally., Tang W; Gene Therapy Center, University of North Carolina at Chapel Hill, 27599 Chapel Hill, North Carolina, USA., Diering GH; Department of Cell Biology and Physiology and UNC Neuroscience Center, University of North Carolina at Chapel Hill, 27599 Chapel Hill, North Carolina, USA.; Carolina Institute for developmental disabilities, 27510 Carrboro, North Carolina., Zou F; Department of Biostatistics, University of North Carolina at Chapel Hill, 27599 Chapel Hill, North Carolina, USA.; Department of Genetics, University of North Carolina at Chapel Hill, 27599 Chapel Hill, North Carolina, USA., Kafri T; Gene Therapy Center, University of North Carolina at Chapel Hill, 27599 Chapel Hill, North Carolina, USA.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, 27599 Chapel Hill, North Carolina.; Lineberger Comprehensive Cancer Center, 27599 Chapel Hill, North Carolina.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 31. Date of Electronic Publication: 2024 Aug 31.

The E3 ubiquitin ligase TRIM9 regulates synaptic function and actin dynamics in response to netrin-1.

Autor: McCormick LE; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Evans EB; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Barker NK; Hooker Proteomics Core, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Herring LE; Hooker Proteomics Core, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Diering GH; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Gupton SL; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.

Publikováno v: Molecular biology of the cell [Mol Biol Cell] 2024 May 01; Vol. 35 (5), pp. ar67. Date of Electronic Publication: 2024 Mar 20.

Evaluating Fatty Acid Amide Hydrolase as a Suitable Target for Sleep Promotion in a Transgenic TauP301S Mouse Model of Neurodegeneration.

Autor: Martin SC; Department of Cell Biology and Physiology and the Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Joyce KK; Department of Cell Biology and Physiology and the Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Harper KM; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Harp SJ; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Cohen TJ; Department of Neurology and the Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Moy SS; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Carolina Institute for Developmental Disabilities, Carrboro, NC 27510, USA., Diering GH; Department of Cell Biology and Physiology and the Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Carolina Institute for Developmental Disabilities, Carrboro, NC 27510, USA.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2024 Feb 29; Vol. 17 (3). Date of Electronic Publication: 2024 Feb 29.

Probing different paradigms of morphine withdrawal on sleep behavior in male and female C57BL/6J mice.

Autor: Bedard ML; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Pharmacology, University North Carolina at Chapel Hill, Chapel Hill, NC, USA., Lord JS; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Perez PJ; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Bravo IM; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Teklezghi AT; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Tarantino LM; Department of Genetics, School of Medicine, University of North Carolina, Chapel Hill, NC, USA; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Diering GH; Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., McElligott ZA; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Pharmacology, University North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: zoemce@email.unc.edu.

Publikováno v: Behavioural brain research [Behav Brain Res] 2023 Jun 25; Vol. 448, pp. 114441. Date of Electronic Publication: 2023 Apr 17.