Cellular zinc homeostasis modulates polarization of THP-1-derived macrophages.

Autor: Dierichs, Laura¹, Kloubert, Veronika¹, Rink, Lothar¹ LRink@UKAachen.de

Publikováno v: European Journal of Nutrition. Sep2018, Vol. 57 Issue 6, p2161-2169. 9p. 1 Black and White Photograph, 6 Graphs.

Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia

Autor: Johansson, Patricia, Dierichs, Laura, Klein-Hitpass, Ludger, Bergmann, Anke K., Möllmann, Michael, Menninger, Sascha, Habenberger, Peter, Klebl, Bert, Siveke, Jens T., Dührsen, Ulrich, Choidas, Axel, Dürig, Jan

Publikováno v: Therapeutic Advances in Hematology, Vol 11 (2020)
Therapeutic Advances in Hematology

T-cell prolymphocytic leukemia (T-PLL) is an aggressive malignancy characterized by chemotherapy resistance and a median survival of less than 2 years. Here, we investigated the pharmacological effects of the novel highly specific cyclin-dependent ki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eb82076dbde758b072f102c9c8875221
https://www.ncbi.nlm.nih.gov/pubmed/33117517

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Anti-leukemic effect of CDK9 inhibition in T-cell prolymphocytic leukemia.

Autor: Johansson P; Department of Hematology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, Essen, D-45122, Germany., Dierichs L; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Hospital Essen, Essen, Germany., Klein-Hitpass L; Institute of Cell Biology (Cancer Research), University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Bergmann AK; Department of Human Genetics, Hannover Medical School, Hannover, Germany., Möllmann M; Department of Hematology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Menninger S; Lead Discovery Center GmbH, Dortmund, Germany., Habenberger P; Lead Discovery Center GmbH, Dortmund, Germany., Klebl B; Lead Discovery Center GmbH, Dortmund, Germany., Siveke JT; Institute for Developmental Cancer Therapeutics, West German Cancer Center, University Hospital Essen, Essen, Germany., Dührsen U; Department of Hematology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Choidas A; Lead Discovery Center GmbH, Dortmund, Germany., Dürig J; Department of Hematology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Publikováno v: Therapeutic advances in hematology [Ther Adv Hematol] 2020 Oct 13; Vol. 11, pp. 2040620720933761. Date of Electronic Publication: 2020 Oct 13 (Print Publication: 2020).