Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Diem Hamai"'
Autor:
Robert A. Jolly, Suren Bandara, Joel Bercu, Courtney M. Callis, David G. Dolan, Jessica Graham, Diem HaMai, Ester Lovsin Barle, Andrew Maier, Melisa Masuda-Herrera, Chandrika Moudgal, Jillian A. Parker, John Reichard, Reena Sandhu, Ernest S. Fung
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 134
Endogenous substances, such as fatty, amino, and nucleic acids, are often purposefully used in parenterally pharmaceuticals, but may be present as impurities. Currently, no consensus guidance exists on setting impurity limits for these substances. Sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2bcf6e3588100ffbd92c6f51b5bf1c
https://pubmed.ncbi.nlm.nih.gov/35964842
https://pubmed.ncbi.nlm.nih.gov/35964842
Autor:
Diem HaMai, Stephen C. Bondy
Publikováno v:
Annals of the New York Academy of Sciences. 1012:129-141
Exposure to excessive levels of manganese, an essential trace element, can evoke severe psychiatric and extrapyramidal motor dysfunction closely resembling Parkinson's disease. The clinical manifestations of manganese toxicity arise from focal injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04278650973b0ee0a742f75a32fa2ba
https://doi.org/10.1196/annals.1306.010
https://doi.org/10.1196/annals.1306.010
Publikováno v:
Current Topics in Medicinal Chemistry. 1:541-551
Cells rely on several transition metals to regulate a wide range of metabolic and signaling functions. The diversity and efficiency of their physiological functions are derived from atomic properties that are specific to transition metals, most notab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7826f87b2a9852b6b4bcf3bc883194e
https://doi.org/10.2174/1568026013394796
https://doi.org/10.2174/1568026013394796
Publikováno v:
NeuroToxicology. 22:63-71
Aluminum is highly oxophilic and its minerals are usually found surrounded by six oxygen atoms. A role for the metal has been established in dialysis encephalopathy and Al-induced osteomalacia. The metal has been implicated in Alzheimer’s disease b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1b3c132eeaab9b553c884c0956389b
https://doi.org/10.1016/s0161-813x(00)00007-3
https://doi.org/10.1016/s0161-813x(00)00007-3
Autor:
Scott S. Shock, Diem Hamai, Yvette W. Lowney, Anne Fairbrother, Joyce S. Tsuji, Deborah Proctor, Steave H. Su, Charles A. Menzie, Michael W. Kierski, Linda M. Ziccardi, Lisa J. Yost, Elizabeth A. Henry, Margaret E. McArdle
Publikováno v:
Environmental sciencetechnology. 43(22)
The recent EPA Framework for Metals Risk Assessment provides the opportunity for contextual risk assessment for sites impacted by metals (such as the depicted Dauntless Mine in Colorado).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394a740e472b9efc26185c9a27443390
https://pubmed.ncbi.nlm.nih.gov/20028040
https://pubmed.ncbi.nlm.nih.gov/20028040
Publikováno v:
Neurotoxicology. 27(3)
Excessive exposure to manganese (Mn) by inhalation can induce psychosis and Parkinsonism. The clinical manifestations of Mn neurotoxicity have been related to numerous physiological and cellular processes, most notably dopamine depletion. However, fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdd1d99991e4f3f09615e40013cd377
https://pubmed.ncbi.nlm.nih.gov/16476481
https://pubmed.ncbi.nlm.nih.gov/16476481
Autor:
Stephen C. Bondy, Diem HaMai
Publikováno v:
HaMai, D; & Bondy, SC. (2004). Pro-or anti-oxidant manganese: A suggested mechanism for reconciliation. Neurochemistry International, 44(4), 223-229. doi: 10.1016/S0197-0186(03)00152-9. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/96q351mk
The neurodegeneration induced by manganese has been attributed to its ability to undergo redox cycling, and catalysis of reactive oxygen species (ROS) formation, as with other transition metals. However, the characterization of manganese as a pro-oxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350c64a18fdb7b887d072708689e16de
http://www.escholarship.org/uc/item/96q351mk
http://www.escholarship.org/uc/item/96q351mk
Publikováno v:
HaMai, D; Campbell, A; & Bondy, SC. (2001). Modulation of oxidative events by multivalent manganese complexes in brain tissue. Free Radical Biology and Medicine, 31(6), 763-768. doi: 10.1016/S0891-5849(01)00639-6. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/90f4b1h2
Manganese toxicity can evoke neuropsychiatric and neuromotor symptoms, which have frequently been attributed to profound oxidative stress in the dopaminergic system. However, the characterization of manganese as a pro-oxidant remains controversial be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a175c2b034bfff0cb1f128d07fc62b
http://www.escholarship.org/uc/item/90f4b1h2
http://www.escholarship.org/uc/item/90f4b1h2