TNFα compromises the inner ear microcirculation in a sphingosine kinase 1/sphingosine-1-phosphate dependent manner – a novel mechanism for sudden hearing loss (SHL)

Autor: Scherer, E, Yang, J, Ivanov, K, Diehl, CD, Reimann, K, Wangemann, P, Canis, M, Strieth, S, Voigtlaender-Bolz, J, Bolz, SS

Publikováno v: 81. Jahresversammlung der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf-und Hals-Chirurgie; 20100512-20100516; Wiesbaden; DOC10hnod421 /20100422/

This study establishes a link between inflammation and inner ear vascular dysfunction. Recovery of auditory function in sudden hearing loss (SHL) patients treated with a TNFα inhibitor were consistent with a vascular origin. We investigated the inne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba7b6e8c514ca7c069466e33cb847c8

Liquid Biopsy in Whole Blood for Identification of Gene Expression Patterns (mRNA and miRNA) Associated with Recurrence of Glioblastoma WHO CNS Grade 4.

Autor: Muhtadi R; Bundeswehr Institute of Radiobiology, 80937 Munich, Germany.; Graduate Center of Medicine and Health, Technical University Munich, 81675 Munich, Germany., Bernhardt D; Department of Radiation Oncology, TUM School of Medicine and Health, Technical University of Munich (TUM), 81675 Munich, Germany., Multhoff G; Department of Radiation Oncology, TUM School of Medicine and Health, Technical University of Munich (TUM), 81675 Munich, Germany., Hönikl L; Department of Neurosurgery, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Combs SE; Department of Radiation Oncology, TUM School of Medicine and Health, Technical University of Munich (TUM), 81675 Munich, Germany.; Deutsches Konsortium für Translational Krebsforschung (DKTK), Partner Site Munich, 80336 Munich, Germany.; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München GmbH, German Research Centre, 85764 Oberschleißheim, Germany., Krieg SM; Department of Neurosurgery, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany.; Department of Neurosurgery, University Hospital Heidelberg, Heidelberg University, 69117 Heidelberg, Germany., Gempt J; Department of Neurosurgery, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany.; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany., Meyer B; Department of Neurosurgery, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Barsegian V; Institute of Nuclear Medicine, Helios Kliniken, 19055 Schwerin, Germany., Lindemann M; Institute for Transfusion Medicine, University Hospital Essen, 45147 Essen, Germany., Kasper M; Bundeswehr Institute of Radiobiology, 80937 Munich, Germany., Stewart S; Bundeswehr Institute of Radiobiology, 80937 Munich, Germany.; Graduate Center of Medicine and Health, Technical University Munich, 81675 Munich, Germany., Port M; Bundeswehr Institute of Radiobiology, 80937 Munich, Germany., Abend M; Bundeswehr Institute of Radiobiology, 80937 Munich, Germany., Diehl CD; Department of Radiation Oncology, TUM School of Medicine and Health, Technical University of Munich (TUM), 81675 Munich, Germany.; Deutsches Konsortium für Translational Krebsforschung (DKTK), Partner Site Munich, 80336 Munich, Germany.; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München GmbH, German Research Centre, 85764 Oberschleißheim, Germany., Ostheim P; Bundeswehr Institute of Radiobiology, 80937 Munich, Germany.

Publikováno v: Cancers [Cancers (Basel)] 2024 Jun 26; Vol. 16 (13). Date of Electronic Publication: 2024 Jun 26.

Opportunities and Alternatives of Modern Radiation Oncology and Surgery for the Management of Resectable Brain Metastases.

Autor: Diehl CD; Department of Radiation Oncology, Technical University of Munich (TUM), Klinikum rechts der Isar, 81675 München, Germany.; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München, 85764 Neuherberg, Germany.; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Munich, 80336 München, Germany., Giordano FA; Department of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany., Grosu AL; Department of Radiation Oncology, University Medical Center, Medical Faculty, 79106 Freiburg, Germany., Ille S; Department of Neurosurgery, Faculty of Medicine, Technical University of Munich, 81675 München, Germany., Kahl KH; Department of Radiation Oncology, University Medical Center Augsburg, 86156 Augsburg, Germany., Onken J; Department of Neurosurgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; Berlin Institute of Health, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Rieken S; Department of Radiotherapy and Radiation Oncology, University Medical Center Göttingen, 37075 Göttingen, Germany.; Comprehensive Cancer Center Niedersachsen (CCC-N), 37075 Göttingen, Germany., Sarria GR; Department of Radiation Oncology, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany., Shiban E; Department of Neurosurgery, University Medical Center Augsburg, 86156 Augsburg, Germany., Wagner A; Department of Neurosurgery, Faculty of Medicine, Technical University of Munich, 81675 München, Germany., Beck J; Department of Neurosurgery, University Hospital Freiburg, 79106 Freiburg, Germany., Brehmer S; Department of Neurosurgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany., Ganslandt O; Neurosurgical Clinic, Klinikum Stuttgart, 70174 Stuttgart, Germany., Hamed M; Department of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany., Meyer B; Department of Neurosurgery, Faculty of Medicine, Technical University of Munich, 81675 München, Germany., Münter M; Department of Radiation Oncology, Klinikum Stuttgart Katharinenhospital, 70174 Stuttgart, Germany., Raabe A; Department of Neurosurgery, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland., Rohde V; Department of Neurosurgery, Universitätsmedizin Göttingen, 37075 Göttingen, Germany., Schaller K; Department of Neurosurgery, University of Geneva Medical Center & Faculty of Medicine, 1211 Geneva, Switzerland., Schilling D; Department of Radiation Oncology, Technical University of Munich (TUM), Klinikum rechts der Isar, 81675 München, Germany.; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München, 85764 Neuherberg, Germany., Schneider M; Department of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany., Sperk E; Mannheim Cancer Center, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany., Thomé C; Department of Neurosurgery, Medical University of Innsbruck, 6020 Innsbruck, Austria., Vajkoczy P; Department of Neurosurgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, 10117 Berlin, Germany., Vatter H; Department of Neurosurgery, University Hospital Bonn, 53127 Bonn, Germany., Combs SE; Department of Radiation Oncology, Technical University of Munich (TUM), Klinikum rechts der Isar, 81675 München, Germany.; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München, 85764 Neuherberg, Germany.; Deutsches Konsortium für Translationale Krebsforschung (DKTK), Partner Site Munich, 80336 München, Germany.

Publikováno v: Cancers [Cancers (Basel)] 2023 Jul 19; Vol. 15 (14). Date of Electronic Publication: 2023 Jul 19.

Low-Energy X-Ray Intraoperative Radiation Therapy (Lex-IORT) for Resected Brain Metastases: A Single-Institution Experience.

Autor: Diehl CD; Department of Radiation Oncology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany.; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München, 85764 Neuherberg, Germany.; Deutsches Konsortium für Translationale Krebsforschung (DKTK), DKTK Partner Site, 81675 Munich, Germany., Pigorsch SU; Department of Radiation Oncology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany.; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München, 85764 Neuherberg, Germany.; Deutsches Konsortium für Translationale Krebsforschung (DKTK), DKTK Partner Site, 81675 Munich, Germany., Gempt J; Department of Neurosurgery, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Krieg SM; Department of Neurosurgery, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany.; TUM-Neuroimaging Center, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Reitz S; Department of Radiation Oncology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Waltenberger M; Department of Radiation Oncology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Barz M; Department of Neurosurgery, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Meyer HS; Department of Neurosurgery, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Wagner A; Department of Neurosurgery, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Wilkens J; Department of Radiation Oncology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Wiestler B; Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Zimmer C; Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Meyer B; Department of Neurosurgery, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany., Combs SE; Department of Radiation Oncology, School of Medicine, Klinikum Rechts der Isar, Technical University of Munich (TUM), 81675 Munich, Germany.; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München, 85764 Neuherberg, Germany.; Deutsches Konsortium für Translationale Krebsforschung (DKTK), DKTK Partner Site, 81675 Munich, Germany.

Publikováno v: Cancers [Cancers (Basel)] 2022 Dec 20; Vol. 15 (1). Date of Electronic Publication: 2022 Dec 20.

nTMS-derived DTI-based motor fiber tracking in radiotherapy treatment planning of high-grade gliomas for avoidance of motor structures.

Autor: Diehl CD; Department of Radiation Oncology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München, Neuherberg, Germany; Deutsches Konsortium für Translationale Krebsforschung (DKTK), DKTK Partner Site, Munich, Germany. Electronic address: Christian.Diehl@tum.de., Rosenkranz E; Department of Radiation Oncology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Department of Neurosurgery, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. Electronic address: Enrike.Rosenkranz@mri.tum.de., Mißlbeck M; Department of Radiation Oncology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. Electronic address: Martin.Misslbeck@tum.de., Schwendner M; Department of Neurosurgery, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. Electronic address: Maximilian.Schwendner@tum.de., Sollmann N; Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; TUM-Neuroimaging Center, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Department of Diagnostic and Interventional Radiology, University Hospital Ulm, Ulm, Germany. Electronic address: Nico.Sollmann@tum.de., Ille S; Department of Neurosurgery, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. Electronic address: Sebastian.Ille@tum.de., Meyer B; Department of Neurosurgery, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. Electronic address: Bernhard.Meyer@tum.de., Combs SE; Department of Radiation Oncology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München, Neuherberg, Germany; Deutsches Konsortium für Translationale Krebsforschung (DKTK), DKTK Partner Site, Munich, Germany. Electronic address: Stephanie.Combs@tum.de., Bernhardt D; Department of Radiation Oncology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München, Neuherberg, Germany; Deutsches Konsortium für Translationale Krebsforschung (DKTK), DKTK Partner Site, Munich, Germany. Electronic address: Denise.Bernhardt@mri.tum.de., Krieg SM; Department of Neurosurgery, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; TUM-Neuroimaging Center, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. Electronic address: Sandro.Krieg@tum.de.

Publikováno v: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2022 Jun; Vol. 171, pp. 189-197. Date of Electronic Publication: 2022 Apr 18.