Lipid–peptide bioconjugation through pyridyl disulfide reaction chemistry and its application in cell targeting and drug delivery

Autor: Diego de la Fuente-Herreruela, Ajay K. Monnappa, Mónica Muñoz-Úbeda, Aarón Morallón-Piña, Eduardo Enciso, Luis Sánchez, Fabrice Giusti, Paolo Natale, Iván López-Montero

Publikováno v: Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-14 (2019)

Abstract Background The design of efficient drug delivery vectors requires versatile formulations able to simultaneously direct a multitude of molecular targets and to bypass the endosomal recycling pathway of cells. Liposomal-based vectors need the

Externí odkaz: https://doaj.org/article/3c75b44569c440eda408609dd2ad7694

Supramolecular zippers elicit interbilayer adhesion of membranes producing cell death

Autor: Víctor G. Almendro-Vedia, Diego de la Fuente-Herreruela, Iván López-Montero, M.H. Viñas, Mónica Muñoz-Úbeda, Carolina García, Rubén Ahijado-Guzmán, M. Pilar Lillo, Rodrigo Q. Albuquerque, Paolo Natale, Andrés Guerrero-Martínez, Francisco Monroy

Publikováno v: E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Biochimica et Biophysica Acta (BBA)-General Subjects
E-Prints Complutense. Archivo Institucional de la UCM
instname
Digital.CSIC. Repositorio Institucional del CSIC
Biochimica et Biophysica Acta. General Subjects

11 pags, 6 figs
Background: The fluorescent dye 10-N-nonyl acridine orange (NAO) is widely used as a mitochondrial marker. NAO was reported to have cytotoxic effects in cultured eukaryotic cells when incubated at high concentrations. Although th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb37fec34f8aa0dc1825f8b84d66c3c
https://eprints.ucm.es/id/eprint/60119/1/BBA2018.pdf